Lan Ruochan
Chapter 154 Penicillium can strengthen Huang Tingjian
Chapter 154 Penicillium can strengthen Huang Tingjian
"Mai girl, is that you?"
"Bah!"
Gao Qiaoni's complexion changed abruptly when he heard the words, and he didn't even hold the food pot firmly in his hand, letting it hit the table.
"In the Shaolin battle that day, I once saw the back of the girl in sackcloth under the moon.
It's just that the girl is so beautiful, it's inevitable that she will attract more attention,
So Wo still remembered that there was a birthmark on the back of the girl's shoulder.
We fought again during the battle of the Tiger Prison, and when I saw the birthmark again, I became suspicious.
Today, when the girl in Mai spoke, she was even more certain.
Takahashi's Chinese is very good without an accent.
Originally, I was still thinking about what kind of magic technique Takahashi Ni practiced to be able to transform into a physical clone.
Now it seems that this should be just a disguise technique, which can modify the faces of the two people to be more similar.
The original Takahashi Ni died in the Hulao, and the Mai girl will continue to pass on Takahashi Ni's name.
Even, there was a bolder guess in my mind.
Eight hundred bhikkhunis, did not really get any longevity method to live eight hundred years,
Instead, in a certain way, this name can be passed on from generation to generation, thus giving people the illusion of being mysterious. "
Qingyun spoke eloquently, the audience was silent, and everyone's eyes were focused on Takahashi's face.
The latter looked terrified and completely at a loss.
At this moment, Jibani suddenly stood up, saluted Qingyun,
"Qing Xiaoxia is really meticulous, but the girl in Mai doesn't speak Chinese well, so it may be difficult to explain.
Let's talk about it from the poor.
Since Qing Xiaoxia had already guessed the details, Pindao didn't hide them either.
But I hope that everyone here will not publicize it, especially for Suga Goryeo and Yubunyu, don't mention it. "
Although Su Wo Gaoli and Yu Wenwen have made great contributions in Hulao, they are now the celebrities that King Wei focuses on protecting.
But because of their bullying faces when they wrestled with Prince Silla, Qingyun didn't have a good impression of them.
At this time, when he heard what Gipernicus said, he nodded immediately.
The other people in the room couldn't help nodding along with the mentality that if you don't eat melons, you are not a hero.
Gibberney knew that all the people present here were famous people and would not break their promise easily, so he sighed and continued,
"The [-]-year-old birthday is a fake story.
Even Peng Zu himself failed to do it.
He just passed on the country for 800 years and wrote Shi Yanzuo.
At that time, none of the other countries had a written history, and only Peng Guoguo did it.
Therefore, the people of the Peng family can count 800 years in the right way,
At that time, the news was blocked, and there were legends in other countries that Peng Zuojun lived for 800 years and knew everything about state affairs.
Later, although the national history of Peng's motherland died, the legend survived.
So many interested people rushed to follow suit, Li Xuandu and Shuzhong Li Babai also played the same tricks.
Mai Shiranui once told you the story of the first Takahashi Ni.
In fact, the mermaid in the story is not a real mermaid, but an aborigine on an isolated island.
They were originally descendants of the Jibai family of Chu State in the Central Plains, and have the same origin as the Jibei family of our country.
Peng Zuo died in Xu State, and Xu State was destroyed by Wu and Chu. The history of Peng Zuo was once hidden in Chu's Taibu, and Jibai tasted it, so he knew this allusion.
On the deserted island, Takahashi Hanqi naturally talked about everything with Ji Bai's daughter. Hearing about this, he had the idea of following suit.
It's just that women's appearance is easy to fade, and this method is especially difficult. Fortunately, Mrs. Jibai is good at plastic surgery for women.
With the help of this magical skill, things will be much easier.
The original Takahashi Ni Takahashi Hanqi is the dream woman you have seen before.
The second-generation Takahashi Ni is the daughter of the mermaid in the mermaid story, Jibei Cainv Dahai, the wife of Ji Xiaogong, the head of the third generation of the Ji family of the six families in Wuchi.
The Jibei family participated in the rebellion against King Jiaduozhilu several times. Jibeicai's daughter Da Haihuo was killed in Silla.
Takahashi's face was gradually declining at that time, so he developed Jibei Cainvhai into the second generation.
Pindao's real name is Jibei Xiaoli, and he is the female general. He has heard the story of the family's daughter Haihai before.
Because his family participated in the rebellion, Pindao was unable to establish himself in Silla Wa, so he also came to Songshan.
When he first came to Songshan, the first member of his own tribe that Pindao met was Abe Sanliujiu's father Yuanzu.
It was he who introduced me to Takahashi.
The second generation of Takahashi Ni lived a miserable life, could not live a long life, and had no choice but to shoulder the responsibility of the third generation.
At that time, Pindao got acquainted with Abe Sanliujiu, and learned that he was the son of the ancestor of the ape, and at last he had a close friendship.
Qing Xiaoxia should have heard that Pindao and Abe Sanliujiu have a daughter, who is the Abe Boyuan you have seen.
The Takahashi Ni you know is already the fourth generation.
She was born in the Gao family in Bohai, so she is also of the same family as Gao Qiao.
Later, Mai Shiranui came to China, and the fourth generation wanted to train him to be the next generation of Takahashi Ni,
Who knows that there are still many things that have not been explained, so she went first.
Fortunately, the poor are still young, and they can continue to hand over the secrets.
The name of Takahashi Ni has been passed down from generation to generation. Long before Pindao joined Baoyi, we had our own goal of serving the Ji family.
In the Korean-Japanese game, the Suwo family has always been the mortal enemy of the Ji family.
Suga Goryeo's father Suga Hanzi poisoned Ji Xiaogong, the husband of the second generation Takahashi Ni, during his expedition to Silla, and seized his army.
Later, injustice was reported, and Suwo Hanzi died in the hands of Ji Xiaogong's son Ji Dapan.
Concluded an indissoluble feud.
Therefore, we have always wanted to kill Suga and Yuwen.
They have tried several times before, and you all know it.
This time in Hulao, they originally planned to win the first prize in dance music, as the finale.
The finale dancers will be invited into the king's seat to toast the guests. This is the best chance for them to assassinate.
Unexpectedly, Miss Mo Chou took the lead in the finale of the dance music, and they were forced to act hastily, only to catch up with someone plotting to assassinate them.
Now Suwo and Yuwen have become hot heroes, under the protection of King Wei,
We can only let go of the internal discord in a small country like ours. "
When Gipernicus spoke, his tone was calm and he did not attach any extra emotion.
But Qingyun still heard some clues from it,
"That day at Hulao Pass, at the family banquet where Ah Hou recognized his godfather and mother,
It's the two Takahashi Ni who want to attack Mo Chou, right? "
Shiranui Mai suddenly bowed to Mo Chou and Qing Yun respectively,
"Hayi, the past, the past.
Mai, wrong.
You guys, save me.
In the future, no.
Eat honey and Masan! "
Mo Chou is quite magnanimous about this matter,
She is a single and weak woman, and she has an oil bottle. There are many people who bullied her in the past, so how can I care about them all.
She hastened to smooth things over,
"Hey, I don't know each other!
We didn't have such friendship before, so some misunderstandings inevitably occurred.
Since Jiperni and Miss Shiranui are so frank, they have told the truth, why should everyone still dwell on those old things.
Hey, has anyone finished their enema?
Shall I add some more for you? "
But although she said it easily, there are still others who care.
Liu Ying snorted heavily and said angrily,
"I don't want to ask more about the previous things.
It's just that Miss Mochou once showed her kindness to her subordinates.
If someone really dares to hit her again,
Even if I, Liu Ying, chased him all the way to the sky, I would make that person repay me ten times over! "
Liu Ying was always direct when he spoke. He only shrank his neck when he heard Takahashi Godaimu, and nodded his head desperately.
Miss Mochou's heart warmed up, her cheeks glowed, but she was too embarrassed to say it, she just picked a few pieces of the most delicate mutton leg, and silently added it to Liu Ying's pot.
Seeing this, Xiao Yan's nose suddenly became sore, and he suddenly felt the autumn wind blowing, and it seemed to be a little chilly.
"""""Knock on the blackboard time"""""
Who listens to Luomei on the jade flute? The original sentence comes from a Tang poem, and the poem has nothing to do with food.The crooked poetry in the article is pure nonsense.It’s just that the author carefully studied the method of this dish when I was reading "The Legend of the Condor Heroes", and then mashed it into a meat paste, and then remade it into strips... There was only one method in ancient times, enema!Speaking of the enema, its method has been recorded in detail in the "Qi Min Yao Shu" mentioned above.The history of enema in China is 2000 years old.
In this article, there is another section of the history of the Japanese country. No one estimates that not many people like to listen to the history of the Japanese country.The Ji clan and the Suga clan belong to the six families of Wu Nei, and they are all relatives within the Wu Fu family.The two clans fell in love and killed each other, and their common ancestor, Laojun Wunei, must be very sad.The story of Takeuchi Laojun is the main content of the second work of this series.The time alignment with the Central Plains is probably in the Three Kingdoms period.Of course, the story begins naturally in my dynasty.Well, do you have any little expectations for the judges?Give some hints of pretending to be there~ Guiqiu~
Of course, there is another reason for writing this history.When we explained the inscription of the Abe family's gold iron sword, why the death year of Emperor Yuraku (King Katojiro) was advanced by the iron sword inscription, this question cannot be answered by Japanese history.But we can, because this sword was forged in China, and the person who made the sword, Timing, has never been back to Japan. He listened to the third generation Yabaichuni Kibi Xiaoli's words about the major events in Japan.The Kibi family was a treacherous minister at the time, and they participated in the conspiracy several times. Kibi Xiaoli may be subjective or objective, thinking that Emperor Yuroku will die due to the Kibi family's calculations.It is normal for the ape ancestor to believe wrongly.
Kibi Xiaoli, the general of the Japanese expedition to Silla, has become a girl in this work~ What's wrong with the girl?The history books didn't say whether she was a girl or not?What's more, in Japan, Ono girl can be a man, but what's wrong with Kibi Xiaoli being a woman?Fiction needs, doesn't make sense.However, in this part of the historical sketch, we still have to restore the objective truth.
Now comes the main course. It is estimated that many readers have already scolded the author for two chapters. They feel that the author is inflated, and it’s okay to talk about ancient surgery. Penicillin has come out!penicillin!You dare not use stalks in time-travel novels, let's see how the author handles them?
Then let's study together, how is the usage of mold in ancient times related to modern penicillin?
First of all, it is necessary for us to introduce modern penicillin and its preparation method.To be precise, the penicillin we are talking about now refers to the solvent of penicillin potassium or sodium salt.The active metal salt of penicillin can be absorbed into the circulatory system so that it can be delivered to the whole body to help the human immune system fight against bacterial invasion.How many steps are there in its preparation method?
[-]. Cultivate mold, this abbreviation.
Second, extraction and refining, which is roughly equivalent to the method used in this article, extracts the effective components with an organic solvent.
Three, activated carbon decolorization, this is simple, so I won’t go into details.
Fourth, salt formation is to make penicillin into potassium salt or sodium salt.Salt-forming agents generally use organic sodium salts (molecular bonds are weak and easy to disengage).
In fact, for the above steps, in ancient times, only salt formation was more difficult.Because it was difficult to synthesize organic potassium sodium salt in ancient times, only inorganic potassium sodium salt was used instead.Inorganic potassium sodium salts are generally stable in structure, and the conversion efficiency to penicillin salts is very low, but it is still possible in solvents (in the form of ions).The solution produced in this way can only be said to contain the components of modern penicillin, and its concentration and efficacy are far lower than those of modern penicillin.However, we must say but, but the drug resistance of bacteria at that time was also poor, and the effect of penicillin was dozens or even hundreds of times that of now!
Having said so much, some readers are getting anxious, don't talk about theory!Come to the real hammer, the real hammer!Did the ancients use mold?Hey, it really will.At this time, we have to take out "Compendium of Materia Medica" and turn to "One of the Valleys: Wheat Seedlings"
There is a line in it: wheat slaves, the Tibetan device said, when the ears of wheat are about to ripen, there are also those with black mold.
Then Mr. Li gave the prescription, and Shi Zhen said: Zhu Gong's "Nanyang Living Book": To cure yang poison, warm poison, heat, extreme madness, spotting, big thirst and double normal, use Hei Nu pill, take one pill with water, Sweating or slight profit will heal.Its prescription uses wheat slave, Liang Shangchen, kettle bottom coal, and Zaotu ink, and divides it into powder with scutellaria baicalensis, ephedra, nitrate, and yellow, and the honeyed pill has a large marble.It is also the meaning of governance for those who take cremation.Wheat is the valley of the heart, which belongs to fire, while slaves are wheat that is about to become solid, steamed by damp heat, and covered with black mold, which is the same as kettle coal and stove ink.Its prescription comes from Chen Yanzhi's "Short Drama Prescription", named Mainu Wan, and Chu Yushi's "Gujin Luyan" named Gaotang Wan and Shujie Wan, which are good medicines for emergency.
Let's take a look at the recipe of this so-called black slave pill: wheat slave is moldy wheat.Liang Shangchen, this is also mold. Referring to the widow's bedside dust, here we can see that the author's use of mold to imitate dust is not fabricated.Bottom ash and stove ink, don't think it is mysterious, this is activated carbon!Scutellaria baicalensis is an antibacterial agent of traditional Chinese medicine. Its effect is the same as that of penicillin. Of course, its effect is different. As an auxiliary drug here, it can help us see clearly what the effect of this drug is.Ephedra is an adjuvant that accelerates absorption and opens pores, and has a certain antiviral effect (not antibacterial, so it can be seen that this formula can prevent bacterial and viral infections to a certain extent).Rhubarb is an adjuvant medicine, anti-inflammatory and beneficial.As for this nitrate, it rarely appears in traditional Chinese medicine. What does it do in this prescription?Of course it is salt, salt!The most common nitrate is potassium salt.Mycin cannot be absorbed without a salt forming agent!
Now you can see the magic of Chinese medicine, right?Penicillium, activated carbon, salt-forming agent, and modern penicillin-making three elements.Of course, it is theoretically impossible to form a salt without forming an ionic solution, so the method of taking this medicine—must be hydrolyzed!Focus!This medicine has been improved for three generations, all emphasizing hydrolysis. It can be seen that the ancient people have fully grasped the preliminary usage of mycin to salt.
What is this prescription used for?Treat high fever!High fever is generally severe inflammation, penicillin, symptomatic!
When did this party first start?Li Shizhen pushed Chen Yanzhi up, who is this?A famous doctor in the Southern Dynasties, Song and Qi Dynasties.The time of the story in this article took place between the Qi and Liang Dynasties in the Southern Dynasties, so before the time of this story, the ancients definitely had a way to use mold salinization to sterilize.Of course, in that era, there is no guarantee that even a doctor can make such a big move, but for our top ones, he must be fine, right?
So in the past, writers dared not use penicillin stems, why not?Use it boldly, with "Lan Ruo Chan Sheng", ah, no, with the support of "Compendium of Materia Medica"!
(End of this chapter)
"Mai girl, is that you?"
"Bah!"
Gao Qiaoni's complexion changed abruptly when he heard the words, and he didn't even hold the food pot firmly in his hand, letting it hit the table.
"In the Shaolin battle that day, I once saw the back of the girl in sackcloth under the moon.
It's just that the girl is so beautiful, it's inevitable that she will attract more attention,
So Wo still remembered that there was a birthmark on the back of the girl's shoulder.
We fought again during the battle of the Tiger Prison, and when I saw the birthmark again, I became suspicious.
Today, when the girl in Mai spoke, she was even more certain.
Takahashi's Chinese is very good without an accent.
Originally, I was still thinking about what kind of magic technique Takahashi Ni practiced to be able to transform into a physical clone.
Now it seems that this should be just a disguise technique, which can modify the faces of the two people to be more similar.
The original Takahashi Ni died in the Hulao, and the Mai girl will continue to pass on Takahashi Ni's name.
Even, there was a bolder guess in my mind.
Eight hundred bhikkhunis, did not really get any longevity method to live eight hundred years,
Instead, in a certain way, this name can be passed on from generation to generation, thus giving people the illusion of being mysterious. "
Qingyun spoke eloquently, the audience was silent, and everyone's eyes were focused on Takahashi's face.
The latter looked terrified and completely at a loss.
At this moment, Jibani suddenly stood up, saluted Qingyun,
"Qing Xiaoxia is really meticulous, but the girl in Mai doesn't speak Chinese well, so it may be difficult to explain.
Let's talk about it from the poor.
Since Qing Xiaoxia had already guessed the details, Pindao didn't hide them either.
But I hope that everyone here will not publicize it, especially for Suga Goryeo and Yubunyu, don't mention it. "
Although Su Wo Gaoli and Yu Wenwen have made great contributions in Hulao, they are now the celebrities that King Wei focuses on protecting.
But because of their bullying faces when they wrestled with Prince Silla, Qingyun didn't have a good impression of them.
At this time, when he heard what Gipernicus said, he nodded immediately.
The other people in the room couldn't help nodding along with the mentality that if you don't eat melons, you are not a hero.
Gibberney knew that all the people present here were famous people and would not break their promise easily, so he sighed and continued,
"The [-]-year-old birthday is a fake story.
Even Peng Zu himself failed to do it.
He just passed on the country for 800 years and wrote Shi Yanzuo.
At that time, none of the other countries had a written history, and only Peng Guoguo did it.
Therefore, the people of the Peng family can count 800 years in the right way,
At that time, the news was blocked, and there were legends in other countries that Peng Zuojun lived for 800 years and knew everything about state affairs.
Later, although the national history of Peng's motherland died, the legend survived.
So many interested people rushed to follow suit, Li Xuandu and Shuzhong Li Babai also played the same tricks.
Mai Shiranui once told you the story of the first Takahashi Ni.
In fact, the mermaid in the story is not a real mermaid, but an aborigine on an isolated island.
They were originally descendants of the Jibai family of Chu State in the Central Plains, and have the same origin as the Jibei family of our country.
Peng Zuo died in Xu State, and Xu State was destroyed by Wu and Chu. The history of Peng Zuo was once hidden in Chu's Taibu, and Jibai tasted it, so he knew this allusion.
On the deserted island, Takahashi Hanqi naturally talked about everything with Ji Bai's daughter. Hearing about this, he had the idea of following suit.
It's just that women's appearance is easy to fade, and this method is especially difficult. Fortunately, Mrs. Jibai is good at plastic surgery for women.
With the help of this magical skill, things will be much easier.
The original Takahashi Ni Takahashi Hanqi is the dream woman you have seen before.
The second-generation Takahashi Ni is the daughter of the mermaid in the mermaid story, Jibei Cainv Dahai, the wife of Ji Xiaogong, the head of the third generation of the Ji family of the six families in Wuchi.
The Jibei family participated in the rebellion against King Jiaduozhilu several times. Jibeicai's daughter Da Haihuo was killed in Silla.
Takahashi's face was gradually declining at that time, so he developed Jibei Cainvhai into the second generation.
Pindao's real name is Jibei Xiaoli, and he is the female general. He has heard the story of the family's daughter Haihai before.
Because his family participated in the rebellion, Pindao was unable to establish himself in Silla Wa, so he also came to Songshan.
When he first came to Songshan, the first member of his own tribe that Pindao met was Abe Sanliujiu's father Yuanzu.
It was he who introduced me to Takahashi.
The second generation of Takahashi Ni lived a miserable life, could not live a long life, and had no choice but to shoulder the responsibility of the third generation.
At that time, Pindao got acquainted with Abe Sanliujiu, and learned that he was the son of the ancestor of the ape, and at last he had a close friendship.
Qing Xiaoxia should have heard that Pindao and Abe Sanliujiu have a daughter, who is the Abe Boyuan you have seen.
The Takahashi Ni you know is already the fourth generation.
She was born in the Gao family in Bohai, so she is also of the same family as Gao Qiao.
Later, Mai Shiranui came to China, and the fourth generation wanted to train him to be the next generation of Takahashi Ni,
Who knows that there are still many things that have not been explained, so she went first.
Fortunately, the poor are still young, and they can continue to hand over the secrets.
The name of Takahashi Ni has been passed down from generation to generation. Long before Pindao joined Baoyi, we had our own goal of serving the Ji family.
In the Korean-Japanese game, the Suwo family has always been the mortal enemy of the Ji family.
Suga Goryeo's father Suga Hanzi poisoned Ji Xiaogong, the husband of the second generation Takahashi Ni, during his expedition to Silla, and seized his army.
Later, injustice was reported, and Suwo Hanzi died in the hands of Ji Xiaogong's son Ji Dapan.
Concluded an indissoluble feud.
Therefore, we have always wanted to kill Suga and Yuwen.
They have tried several times before, and you all know it.
This time in Hulao, they originally planned to win the first prize in dance music, as the finale.
The finale dancers will be invited into the king's seat to toast the guests. This is the best chance for them to assassinate.
Unexpectedly, Miss Mo Chou took the lead in the finale of the dance music, and they were forced to act hastily, only to catch up with someone plotting to assassinate them.
Now Suwo and Yuwen have become hot heroes, under the protection of King Wei,
We can only let go of the internal discord in a small country like ours. "
When Gipernicus spoke, his tone was calm and he did not attach any extra emotion.
But Qingyun still heard some clues from it,
"That day at Hulao Pass, at the family banquet where Ah Hou recognized his godfather and mother,
It's the two Takahashi Ni who want to attack Mo Chou, right? "
Shiranui Mai suddenly bowed to Mo Chou and Qing Yun respectively,
"Hayi, the past, the past.
Mai, wrong.
You guys, save me.
In the future, no.
Eat honey and Masan! "
Mo Chou is quite magnanimous about this matter,
She is a single and weak woman, and she has an oil bottle. There are many people who bullied her in the past, so how can I care about them all.
She hastened to smooth things over,
"Hey, I don't know each other!
We didn't have such friendship before, so some misunderstandings inevitably occurred.
Since Jiperni and Miss Shiranui are so frank, they have told the truth, why should everyone still dwell on those old things.
Hey, has anyone finished their enema?
Shall I add some more for you? "
But although she said it easily, there are still others who care.
Liu Ying snorted heavily and said angrily,
"I don't want to ask more about the previous things.
It's just that Miss Mochou once showed her kindness to her subordinates.
If someone really dares to hit her again,
Even if I, Liu Ying, chased him all the way to the sky, I would make that person repay me ten times over! "
Liu Ying was always direct when he spoke. He only shrank his neck when he heard Takahashi Godaimu, and nodded his head desperately.
Miss Mochou's heart warmed up, her cheeks glowed, but she was too embarrassed to say it, she just picked a few pieces of the most delicate mutton leg, and silently added it to Liu Ying's pot.
Seeing this, Xiao Yan's nose suddenly became sore, and he suddenly felt the autumn wind blowing, and it seemed to be a little chilly.
"""""Knock on the blackboard time"""""
Who listens to Luomei on the jade flute? The original sentence comes from a Tang poem, and the poem has nothing to do with food.The crooked poetry in the article is pure nonsense.It’s just that the author carefully studied the method of this dish when I was reading "The Legend of the Condor Heroes", and then mashed it into a meat paste, and then remade it into strips... There was only one method in ancient times, enema!Speaking of the enema, its method has been recorded in detail in the "Qi Min Yao Shu" mentioned above.The history of enema in China is 2000 years old.
In this article, there is another section of the history of the Japanese country. No one estimates that not many people like to listen to the history of the Japanese country.The Ji clan and the Suga clan belong to the six families of Wu Nei, and they are all relatives within the Wu Fu family.The two clans fell in love and killed each other, and their common ancestor, Laojun Wunei, must be very sad.The story of Takeuchi Laojun is the main content of the second work of this series.The time alignment with the Central Plains is probably in the Three Kingdoms period.Of course, the story begins naturally in my dynasty.Well, do you have any little expectations for the judges?Give some hints of pretending to be there~ Guiqiu~
Of course, there is another reason for writing this history.When we explained the inscription of the Abe family's gold iron sword, why the death year of Emperor Yuraku (King Katojiro) was advanced by the iron sword inscription, this question cannot be answered by Japanese history.But we can, because this sword was forged in China, and the person who made the sword, Timing, has never been back to Japan. He listened to the third generation Yabaichuni Kibi Xiaoli's words about the major events in Japan.The Kibi family was a treacherous minister at the time, and they participated in the conspiracy several times. Kibi Xiaoli may be subjective or objective, thinking that Emperor Yuroku will die due to the Kibi family's calculations.It is normal for the ape ancestor to believe wrongly.
Kibi Xiaoli, the general of the Japanese expedition to Silla, has become a girl in this work~ What's wrong with the girl?The history books didn't say whether she was a girl or not?What's more, in Japan, Ono girl can be a man, but what's wrong with Kibi Xiaoli being a woman?Fiction needs, doesn't make sense.However, in this part of the historical sketch, we still have to restore the objective truth.
Now comes the main course. It is estimated that many readers have already scolded the author for two chapters. They feel that the author is inflated, and it’s okay to talk about ancient surgery. Penicillin has come out!penicillin!You dare not use stalks in time-travel novels, let's see how the author handles them?
Then let's study together, how is the usage of mold in ancient times related to modern penicillin?
First of all, it is necessary for us to introduce modern penicillin and its preparation method.To be precise, the penicillin we are talking about now refers to the solvent of penicillin potassium or sodium salt.The active metal salt of penicillin can be absorbed into the circulatory system so that it can be delivered to the whole body to help the human immune system fight against bacterial invasion.How many steps are there in its preparation method?
[-]. Cultivate mold, this abbreviation.
Second, extraction and refining, which is roughly equivalent to the method used in this article, extracts the effective components with an organic solvent.
Three, activated carbon decolorization, this is simple, so I won’t go into details.
Fourth, salt formation is to make penicillin into potassium salt or sodium salt.Salt-forming agents generally use organic sodium salts (molecular bonds are weak and easy to disengage).
In fact, for the above steps, in ancient times, only salt formation was more difficult.Because it was difficult to synthesize organic potassium sodium salt in ancient times, only inorganic potassium sodium salt was used instead.Inorganic potassium sodium salts are generally stable in structure, and the conversion efficiency to penicillin salts is very low, but it is still possible in solvents (in the form of ions).The solution produced in this way can only be said to contain the components of modern penicillin, and its concentration and efficacy are far lower than those of modern penicillin.However, we must say but, but the drug resistance of bacteria at that time was also poor, and the effect of penicillin was dozens or even hundreds of times that of now!
Having said so much, some readers are getting anxious, don't talk about theory!Come to the real hammer, the real hammer!Did the ancients use mold?Hey, it really will.At this time, we have to take out "Compendium of Materia Medica" and turn to "One of the Valleys: Wheat Seedlings"
There is a line in it: wheat slaves, the Tibetan device said, when the ears of wheat are about to ripen, there are also those with black mold.
Then Mr. Li gave the prescription, and Shi Zhen said: Zhu Gong's "Nanyang Living Book": To cure yang poison, warm poison, heat, extreme madness, spotting, big thirst and double normal, use Hei Nu pill, take one pill with water, Sweating or slight profit will heal.Its prescription uses wheat slave, Liang Shangchen, kettle bottom coal, and Zaotu ink, and divides it into powder with scutellaria baicalensis, ephedra, nitrate, and yellow, and the honeyed pill has a large marble.It is also the meaning of governance for those who take cremation.Wheat is the valley of the heart, which belongs to fire, while slaves are wheat that is about to become solid, steamed by damp heat, and covered with black mold, which is the same as kettle coal and stove ink.Its prescription comes from Chen Yanzhi's "Short Drama Prescription", named Mainu Wan, and Chu Yushi's "Gujin Luyan" named Gaotang Wan and Shujie Wan, which are good medicines for emergency.
Let's take a look at the recipe of this so-called black slave pill: wheat slave is moldy wheat.Liang Shangchen, this is also mold. Referring to the widow's bedside dust, here we can see that the author's use of mold to imitate dust is not fabricated.Bottom ash and stove ink, don't think it is mysterious, this is activated carbon!Scutellaria baicalensis is an antibacterial agent of traditional Chinese medicine. Its effect is the same as that of penicillin. Of course, its effect is different. As an auxiliary drug here, it can help us see clearly what the effect of this drug is.Ephedra is an adjuvant that accelerates absorption and opens pores, and has a certain antiviral effect (not antibacterial, so it can be seen that this formula can prevent bacterial and viral infections to a certain extent).Rhubarb is an adjuvant medicine, anti-inflammatory and beneficial.As for this nitrate, it rarely appears in traditional Chinese medicine. What does it do in this prescription?Of course it is salt, salt!The most common nitrate is potassium salt.Mycin cannot be absorbed without a salt forming agent!
Now you can see the magic of Chinese medicine, right?Penicillium, activated carbon, salt-forming agent, and modern penicillin-making three elements.Of course, it is theoretically impossible to form a salt without forming an ionic solution, so the method of taking this medicine—must be hydrolyzed!Focus!This medicine has been improved for three generations, all emphasizing hydrolysis. It can be seen that the ancient people have fully grasped the preliminary usage of mycin to salt.
What is this prescription used for?Treat high fever!High fever is generally severe inflammation, penicillin, symptomatic!
When did this party first start?Li Shizhen pushed Chen Yanzhi up, who is this?A famous doctor in the Southern Dynasties, Song and Qi Dynasties.The time of the story in this article took place between the Qi and Liang Dynasties in the Southern Dynasties, so before the time of this story, the ancients definitely had a way to use mold salinization to sterilize.Of course, in that era, there is no guarantee that even a doctor can make such a big move, but for our top ones, he must be fine, right?
So in the past, writers dared not use penicillin stems, why not?Use it boldly, with "Lan Ruo Chan Sheng", ah, no, with the support of "Compendium of Materia Medica"!
(End of this chapter)
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