Daming Town Haiwang
Chapter 1005, Vaccinia Prevention
Chapter 1005, Vaccinia Prevention
Quickly collected some samples, Li Anyuan also hurriedly led people away from this plague city. Almost everyone here has been infected with smallpox, and coupled with such ignorance, they would rather believe in ghosts and gods than Daming. With the method of prevention and control, everyone in this city will die.
"Professor Li, according to the analysis of the samples collected from the surrounding areas, all the smallpox viruses are the same as the smallpox viruses that appeared in our Daming side, there is no difference."
Back at Baiyin Port, Li Anyuan's team never stopped, running around, collecting samples continuously, and analyzing the epidemic situation in the entire Aztec Kingdom at the same time.
"Judging from the current situation, the epidemic situation in the Aztec Kingdom has reached the verge of getting out of control, and it may break out completely at any time. At that time, it will not only destroy the entire Aztec Kingdom, but also our Ming Dynasty. These colonial towns will also be implicated."
"We must find a way to solve this problem as soon as possible."
Li Anyuan frowned after listening to his subordinates' report.
The situation is even worse than what I saw. The smallpox virus has spread on a large scale. The key is that these people in the Aztec Kingdom are very superstitious and did not strictly follow the requirements of Ming Dynasty, so that smallpox The spread of the virus is beyond imagination.
"Relying on isolation is definitely not enough. Now we can only try the vaccinia prevention method that Mr. Liu said."
Although the smallpox virus is terrible, with a high mortality rate and strong transmissibility, since ancient times, a lot of experience has been accumulated in the long-term confrontation with the smallpox virus.
In the Song Dynasty, there was a medical book "A Pox Conclusive Theory" that recorded related things, which mentioned that there are people in Sichuan who are good at vaccination, and those who have been vaccinated will never get smallpox again.
From this, we can know that there was already a way to deal with smallpox in the past, that is, to achieve the preventive effect through vaccination against smallpox.
However, the method of planting human pox will bring serious adverse reactions, and even has a certain percentage of fatality, and its safety is far inferior to that of the popular vaccinia vaccination method in later generations.
Li Anyuan came to Golden Continent this time, on the one hand, he naturally wanted to find a way to control the outbreak of smallpox virus on the Golden Continent, and prevent the smallpox virus from spreading to Daming.
You must know that the current Ming Dynasty, especially the Beijing-Tianjin area, is too densely populated. Once a person carrying the smallpox virus flees to the Beijing-Tianjin area, the consequences will be unimaginable.
Therefore, it is necessary to stop it at the source, so that the smallpox virus from the Golden Continent cannot spread to Daming.
Of course, the most important thing is to find a way to prevent and treat the smallpox virus. It is definitely not the way to always be on guard.
The population in the Beijing-Tianjin area is very large and dense, and with the development of sea transportation and highways, not only the exchanges between various places in Ming Dynasty have become closer and more frequent, the exchanges between Ming Dynasty and all parts of the world will also change. more intensive and frequent.
This means that many local diseases may be transmitted to Ming Dynasty, and smallpox is only one of them. Without strong medical technology and medical team, it is very likely that the history of Europeans will repeat itself when faced with terrible diseases. .
The most effective way to deal with smallpox is to prevent it. Everyone will be vaccinated against it. Naturally, there is nothing to be afraid of.
Li Anyuan soon found Wu Lin, the county magistrate of Baiyin Port, and put forward his views and demands to him.
"Professor Li, don't worry, I will immediately contact Montezuma II of the Aztec Kingdom and ask him to get some people to come and experiment."
After listening to Li Anyuan's words, Wu Lin also realized the seriousness of this matter, and he also clearly knew why the imperial court sent Li Anyuan here.
This is not just to help the Aztec Kingdom, but also to research ways to prevent smallpox for Daming.
"It's work!"
Li Anyuan quickly thanked him, and then made some other requests, such as the isolated area, and there is still a certain amount of manpower needed for medical treatment.
Wu Lin's actions were very fast. In just a few days, he got more than a hundred people from the Aztec Kingdom, which was very easy and simple.
Tian Erniu conquered the Aztec kingdom with force and religion, making them believe that the Ming people and they are the people of the sun god, but they made a mistake, so they were exiled here, and now they have sent down the plague god to punish them.
For this reason, the Aztec Kingdom even boasted that they would pay double the gold and silver tribute this year, build a larger pyramid to atone for the sun god, and ask the gods to forgive their sins.
Regarding Daming's request, the Aztec Kingdom agreed without hesitation, and sent over a hundred people to participate in Li Anyuan's experiment.
In a separate isolated area of Baiyingang, more than a hundred descendants of wealthy merchants, male and female, old and young, are queuing up to be vaccinated.
Wearing a white coat and a mask, Li Anyuan carefully watched his apprentices inoculate these people.
"I don't know if the method of vaccinia vaccination can prevent smallpox. If it doesn't work, I'm afraid the Golden Island will be blocked by then."
"But too many, too many people have married local women as wives and concubines, leaving millions of children. If this method doesn't work, the only way to prevent it is to rely on mandatory isolation." gone."
Li Anyuan looked at the team in front of him with a sad face.
Because it is experimental in nature, Li Anyuan's team also adopted several methods of borrowing seeds. There is a traditional method of borrowing seeds, drying the vaccinia powder and blowing it into the nostrils, wiping the body with clothes soaked in vaccinia, and There are people who pricked the skin with needles directly on their hands and feet, and then got infected with cowpox... Various methods are tentative, but fortunately, there are not many people.
So the speed is very fast. In less than an hour, more than one hundred local aborigines have completed the vaccination.
Perhaps it was because the local aborigines in the Golden Continent really lacked immunity to the smallpox virus. After the vaccination was completed, more than a hundred people immediately developed symptoms of discomfort on the same day.
"Record all in detail, what kind of symptoms each person has, what is the body temperature, what is the pulse, what is the heartbeat, whether there is a fever, etc."
"This information is very important and must be detailed!"
Li Anyuan's team quickly got busy, this is an extremely rare experiment.
You must know that this experiment is conducted with human life, and the danger is very high. If the experiment fails, these more than a hundred people will most likely die due to infection with the smallpox virus.
It is forbidden to use living people for experiments.
But medicine sometimes has to do this, especially in this era when we don't know how to use mice to experiment. If you want to quickly know the therapeutic effect of a drug on a certain disease, the easiest and most direct way is to use the human body. test.
This is also the reason why Liu Jin sent them to the Golden Continent, because the Golden Continent happens to have a large number of experimental subjects and a large amount of experimental materials, which is enough for Li Anyuan to develop a method of borrowing vaccinia come out.
The whole team was busy quickly, classifying and summarizing each patient in detail, and at the same time began to test the symptoms of these people.
"Judging from the current situation, the method of pricking blood with needles is the most effective method. All the people who used this method, whether it was on their hands or legs, were infected with smallpox in the first place, and smallpox began to appear. Smallpox-related illness."
"Judging from the current situation, everyone's symptoms are under control. Although there are some herpes on the body, they are very small and disappear soon."
"The symptoms of the vaccinated patients are very mild, far less severe than the ones inoculated with smallpox in Daming, and the adverse reactions are much lighter."
"Scabs appeared at the inoculation site. From the removed scabs, it can be seen through a microscope that there is smallpox virus in it, which indicates that it has been infected with smallpox virus."
Li Anyuan is constantly analyzing and summarizing every day.
After a few days, more than one hundred descendants of wealthy merchants who had been inoculated with vaccinia all recovered completely, and all of them were fine.
"Everything is fine, now comes the most critical part, to see if antibodies have been produced, if antibodies have been produced, this shows that the method of vaccinia vaccination is indeed feasible."
"Compared to the traditional method of varicella vaccination, the method of vaccinia vaccination is safer and more reliable, and the adverse reactions are very small. Even for these descendants of rich merchants, their adverse reactions are not very big, they are just feeling unwell, just take a break for a day or two. After a few days, it will soon be back to normal."
Seeing the results of the experiment, Li Anyuan's team couldn't help cheering, because judging from the results of the experiment, none of the more than one hundred people died. Although some people had some serious adverse reactions during the experiment, they recovered quickly. .
"Inject them with smallpox!"
Li Anyuan suppressed the excitement in his heart. If he could find out the method of preventing smallpox virus from cowpox, his name would definitely be written in history.
He would become the first person in history to develop a truly effective anti-smallpox virus.
Smallpox, this is an extremely terrible disease, a disease that makes people look pale.
In Daming, there are reported cases every year, and at least a few thousand people die from smallpox almost every year. This is because Daming has already figured out a relatively mature and reliable countermeasure.
On the European side, because of the lack of effective countermeasures, smallpox is like the Black Death plague in the Middle Ages, which has claimed many lives. It is too contagious and has a very high mortality rate.
This is a disease that makes people blush, but now I am about to master the method of restraint.
I saw the Black Death plague in the Middle Ages in Europe. It was really terrible. One-third of the people were killed~ Well, it was mainly related to their dislike of bathing.
(End of this chapter)
Quickly collected some samples, Li Anyuan also hurriedly led people away from this plague city. Almost everyone here has been infected with smallpox, and coupled with such ignorance, they would rather believe in ghosts and gods than Daming. With the method of prevention and control, everyone in this city will die.
"Professor Li, according to the analysis of the samples collected from the surrounding areas, all the smallpox viruses are the same as the smallpox viruses that appeared in our Daming side, there is no difference."
Back at Baiyin Port, Li Anyuan's team never stopped, running around, collecting samples continuously, and analyzing the epidemic situation in the entire Aztec Kingdom at the same time.
"Judging from the current situation, the epidemic situation in the Aztec Kingdom has reached the verge of getting out of control, and it may break out completely at any time. At that time, it will not only destroy the entire Aztec Kingdom, but also our Ming Dynasty. These colonial towns will also be implicated."
"We must find a way to solve this problem as soon as possible."
Li Anyuan frowned after listening to his subordinates' report.
The situation is even worse than what I saw. The smallpox virus has spread on a large scale. The key is that these people in the Aztec Kingdom are very superstitious and did not strictly follow the requirements of Ming Dynasty, so that smallpox The spread of the virus is beyond imagination.
"Relying on isolation is definitely not enough. Now we can only try the vaccinia prevention method that Mr. Liu said."
Although the smallpox virus is terrible, with a high mortality rate and strong transmissibility, since ancient times, a lot of experience has been accumulated in the long-term confrontation with the smallpox virus.
In the Song Dynasty, there was a medical book "A Pox Conclusive Theory" that recorded related things, which mentioned that there are people in Sichuan who are good at vaccination, and those who have been vaccinated will never get smallpox again.
From this, we can know that there was already a way to deal with smallpox in the past, that is, to achieve the preventive effect through vaccination against smallpox.
However, the method of planting human pox will bring serious adverse reactions, and even has a certain percentage of fatality, and its safety is far inferior to that of the popular vaccinia vaccination method in later generations.
Li Anyuan came to Golden Continent this time, on the one hand, he naturally wanted to find a way to control the outbreak of smallpox virus on the Golden Continent, and prevent the smallpox virus from spreading to Daming.
You must know that the current Ming Dynasty, especially the Beijing-Tianjin area, is too densely populated. Once a person carrying the smallpox virus flees to the Beijing-Tianjin area, the consequences will be unimaginable.
Therefore, it is necessary to stop it at the source, so that the smallpox virus from the Golden Continent cannot spread to Daming.
Of course, the most important thing is to find a way to prevent and treat the smallpox virus. It is definitely not the way to always be on guard.
The population in the Beijing-Tianjin area is very large and dense, and with the development of sea transportation and highways, not only the exchanges between various places in Ming Dynasty have become closer and more frequent, the exchanges between Ming Dynasty and all parts of the world will also change. more intensive and frequent.
This means that many local diseases may be transmitted to Ming Dynasty, and smallpox is only one of them. Without strong medical technology and medical team, it is very likely that the history of Europeans will repeat itself when faced with terrible diseases. .
The most effective way to deal with smallpox is to prevent it. Everyone will be vaccinated against it. Naturally, there is nothing to be afraid of.
Li Anyuan soon found Wu Lin, the county magistrate of Baiyin Port, and put forward his views and demands to him.
"Professor Li, don't worry, I will immediately contact Montezuma II of the Aztec Kingdom and ask him to get some people to come and experiment."
After listening to Li Anyuan's words, Wu Lin also realized the seriousness of this matter, and he also clearly knew why the imperial court sent Li Anyuan here.
This is not just to help the Aztec Kingdom, but also to research ways to prevent smallpox for Daming.
"It's work!"
Li Anyuan quickly thanked him, and then made some other requests, such as the isolated area, and there is still a certain amount of manpower needed for medical treatment.
Wu Lin's actions were very fast. In just a few days, he got more than a hundred people from the Aztec Kingdom, which was very easy and simple.
Tian Erniu conquered the Aztec kingdom with force and religion, making them believe that the Ming people and they are the people of the sun god, but they made a mistake, so they were exiled here, and now they have sent down the plague god to punish them.
For this reason, the Aztec Kingdom even boasted that they would pay double the gold and silver tribute this year, build a larger pyramid to atone for the sun god, and ask the gods to forgive their sins.
Regarding Daming's request, the Aztec Kingdom agreed without hesitation, and sent over a hundred people to participate in Li Anyuan's experiment.
In a separate isolated area of Baiyingang, more than a hundred descendants of wealthy merchants, male and female, old and young, are queuing up to be vaccinated.
Wearing a white coat and a mask, Li Anyuan carefully watched his apprentices inoculate these people.
"I don't know if the method of vaccinia vaccination can prevent smallpox. If it doesn't work, I'm afraid the Golden Island will be blocked by then."
"But too many, too many people have married local women as wives and concubines, leaving millions of children. If this method doesn't work, the only way to prevent it is to rely on mandatory isolation." gone."
Li Anyuan looked at the team in front of him with a sad face.
Because it is experimental in nature, Li Anyuan's team also adopted several methods of borrowing seeds. There is a traditional method of borrowing seeds, drying the vaccinia powder and blowing it into the nostrils, wiping the body with clothes soaked in vaccinia, and There are people who pricked the skin with needles directly on their hands and feet, and then got infected with cowpox... Various methods are tentative, but fortunately, there are not many people.
So the speed is very fast. In less than an hour, more than one hundred local aborigines have completed the vaccination.
Perhaps it was because the local aborigines in the Golden Continent really lacked immunity to the smallpox virus. After the vaccination was completed, more than a hundred people immediately developed symptoms of discomfort on the same day.
"Record all in detail, what kind of symptoms each person has, what is the body temperature, what is the pulse, what is the heartbeat, whether there is a fever, etc."
"This information is very important and must be detailed!"
Li Anyuan's team quickly got busy, this is an extremely rare experiment.
You must know that this experiment is conducted with human life, and the danger is very high. If the experiment fails, these more than a hundred people will most likely die due to infection with the smallpox virus.
It is forbidden to use living people for experiments.
But medicine sometimes has to do this, especially in this era when we don't know how to use mice to experiment. If you want to quickly know the therapeutic effect of a drug on a certain disease, the easiest and most direct way is to use the human body. test.
This is also the reason why Liu Jin sent them to the Golden Continent, because the Golden Continent happens to have a large number of experimental subjects and a large amount of experimental materials, which is enough for Li Anyuan to develop a method of borrowing vaccinia come out.
The whole team was busy quickly, classifying and summarizing each patient in detail, and at the same time began to test the symptoms of these people.
"Judging from the current situation, the method of pricking blood with needles is the most effective method. All the people who used this method, whether it was on their hands or legs, were infected with smallpox in the first place, and smallpox began to appear. Smallpox-related illness."
"Judging from the current situation, everyone's symptoms are under control. Although there are some herpes on the body, they are very small and disappear soon."
"The symptoms of the vaccinated patients are very mild, far less severe than the ones inoculated with smallpox in Daming, and the adverse reactions are much lighter."
"Scabs appeared at the inoculation site. From the removed scabs, it can be seen through a microscope that there is smallpox virus in it, which indicates that it has been infected with smallpox virus."
Li Anyuan is constantly analyzing and summarizing every day.
After a few days, more than one hundred descendants of wealthy merchants who had been inoculated with vaccinia all recovered completely, and all of them were fine.
"Everything is fine, now comes the most critical part, to see if antibodies have been produced, if antibodies have been produced, this shows that the method of vaccinia vaccination is indeed feasible."
"Compared to the traditional method of varicella vaccination, the method of vaccinia vaccination is safer and more reliable, and the adverse reactions are very small. Even for these descendants of rich merchants, their adverse reactions are not very big, they are just feeling unwell, just take a break for a day or two. After a few days, it will soon be back to normal."
Seeing the results of the experiment, Li Anyuan's team couldn't help cheering, because judging from the results of the experiment, none of the more than one hundred people died. Although some people had some serious adverse reactions during the experiment, they recovered quickly. .
"Inject them with smallpox!"
Li Anyuan suppressed the excitement in his heart. If he could find out the method of preventing smallpox virus from cowpox, his name would definitely be written in history.
He would become the first person in history to develop a truly effective anti-smallpox virus.
Smallpox, this is an extremely terrible disease, a disease that makes people look pale.
In Daming, there are reported cases every year, and at least a few thousand people die from smallpox almost every year. This is because Daming has already figured out a relatively mature and reliable countermeasure.
On the European side, because of the lack of effective countermeasures, smallpox is like the Black Death plague in the Middle Ages, which has claimed many lives. It is too contagious and has a very high mortality rate.
This is a disease that makes people blush, but now I am about to master the method of restraint.
I saw the Black Death plague in the Middle Ages in Europe. It was really terrible. One-third of the people were killed~ Well, it was mainly related to their dislike of bathing.
(End of this chapter)
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