godfather of surgery

Chapter 1071 Fourth Uncle
The rabies patient at the Nandu Hospital is still in a coma, but this is an active and controlled coma, or hibernation therapy, which allows the brain to stop working and avoid the effects of hypoxia on brain cells caused by complications. It is like actively freezing a piece of fresh meat in the refrigerator to avoid damage caused by high temperature weather.

After a few days of treatment, the antibody titer of rabies virus has not changed much, but Yang Ping is not in a hurry now, he can only wait patiently for the disease to turn around. His new plan can only protect the brain from damage, and the human body's own immune system is still needed to fight against rabies virus.

For this patient, the leader of the National Health Commission called Professor Su almost every day to inquire about the patient's condition. Although he knew that the final outcome would not change, he still hoped for a miracle. If this young scientist had an accident, an important national defense project would be delayed. The leader was also confused by the thought of how he could suffer from this incurable disease.

Without vaccination, once rabies breaks out, the mortality rate is 100%. The leader is also a medical expert and understands this very well.

However, when they heard that Yang Ping was using some new treatment method, the Health Commission leaders' eyes lit up again. This young man was a top candidate in everyone's mind. He had a new method, which meant that there was still a glimmer of hope for this patient.

The leader of the Health Commission immediately became happy: "Lao Su, if you really save the person, I will give you a great credit. In the future, when you come to my place to do things, you will get a green light all the way. Of course, it must be something I can do and it does not violate the principles."

Lao Su also seized this rare opportunity: "You said it, don't deny it when the time comes."

This leader and Professor Su are good friends and have a very good relationship, so the two of them chatted quite easily.

In fact, Professor Su knew very well that there would be no risk in using the new method in this case no matter from which angle, so he strongly encouraged Yang Ping to use it. What was there to worry about in a case with a 100% mortality rate? Since there was a glimmer of hope, he should just go all out.

To put it bluntly, if you save the person, you get credit; if you don't, there's nothing wrong with that, because it would be the same even without using new methods.

The leader of the Health Commission had just finished the call when Director Liu of 301 called. Director Liu knew that Yang Ping was leading the treatment, so he had no choice but to do it. If he couldn't do it, then no one could. Director Liu also sent experts, but it was just a formality to show an attitude. With Yang Ping there, who would dare to give guidance?

The leaders of both sides had just finished a phone call, and Professor Su's cell phone was hot. Leaders from the General Logistics Department and the Commission of Science and Technology called, and one of the leaders was Su Laosi from his family.

Because this young scientist was so important, Su Laosi decided to go and see for himself, and also to visit his nephew's husband. Although his second brother had described him in such fantastic terms, he had never seen him before.

Su Qinghe had heard of this nephew's husband many times, but had never met him. This time he happened to meet him.
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Yang Ping participates in the daily treatment summary meeting. Not only experts from the First Affiliated Hospital of Nanjing University of the Arts participate, but experts from several other hospitals also participate via video link, including Union Hospital, 301 Hospital, West China Hospital, etc.

To sum up now, the doctor had no problem in diagnosis and discovered the disease very early.

Let's review this patient now. The patient's name is Chang Qirui, 39 years old, male. On the second day after he went home to visit his family, he occasionally felt numbness and tingling in his right hand. At that time, he did not pay attention to it, thinking that it was just a cervical spondylosis attack, and took a diclofenac sodium painkiller. On the third day, he had double vision in front of his eyes, and on the fourth day, he felt dizzy, nauseous and vomited. At this time, the patient found something wrong and immediately told his colleagues about his discomfort.

There was a health care doctor with him, but he was a general practitioner. He immediately arranged for Professor Chang to come to the emergency department of the First Affiliated Hospital of Nandu Hospital for treatment. At that time, the entire diagnosis and treatment process was arranged by Professor Su himself. The emergency department of the First Affiliated Hospital immediately gave him an MRI examination, but no abnormalities were found. On the day of the consultation, the patient's condition worsened: he suddenly had a high fever and could not move the right half of his body.

This was a big deal, so the patient was immediately hospitalized. But where? In order to facilitate treatment, he was directly admitted to the ICU. The first neurologist he consulted was Director Qi of the Department of Neurology. He found that the patient had tremors and flaccid paralysis on the right side of his body. He immediately did a routine cerebrospinal fluid test and biochemistry test on the patient, which showed that he was infected with a virus. However, all the virus test results were indeed negative.

This put Director Qi in a difficult position. In order to consolidate the strength of the First Affiliated Hospital, Professor Su immediately arranged for an emergency consultation with Director Yuan from the infectious department. When Director Yuan arrived, the patient was already gurgling with bubbles in his mouth.

Due to the popularization of rabies vaccines, the number of rabies cases each year is actually very small. There are only more than 100 cases each year. If more than 100 cases are spread across China, there are only a few cases in one province, which can be said to be very few.

But the First Affiliated Hospital is the First Affiliated Hospital. After thinking about it for a while, Director Yuan of the Infectious Diseases Department immediately realized that something was wrong: extremely atypical neurological symptoms, drooling, fever, and viral infection.

Then a disease popped into his mind - rabies. He immediately contacted the patient's family and asked if the patient had ever been bitten by dogs, cats or other animals.

The family members were also confused at the time, but her wife said that she heard from the patient that when he just graduated with a Ph.D., he went hiking with his roommates and was bitten by a wild dog. The injury was not serious at the time, just a few teeth marks that broke the skin, so no one took it seriously and did not get vaccinated.

After hearing this medical history, Director Yuan was almost certain that the patient had rabies.

Soon, the laboratory of the First Affiliated Hospital found antibodies to the rabies virus in the patient's cerebrospinal fluid and blood, and rabies was confirmed.

In fact, following this line of thought, the diagnosis was very timely, without any delay, and the treatment was also timely. As soon as he arrived at the First Affiliated Hospital, he was admitted to the ICU for symptomatic treatment.

Rabies is a disease that doctors fear because of its 100% mortality rate. Its incubation period can be as short as a week or as long as ten years. When the disease occurs, the patient will be extremely excited, sometimes violent, and have specific hydrophobia.

Director Yuan from the infectious department reviewed the patient's diagnosis and treatment process. There were no problems. Now the question was how to treat him.

How to treat the disease will now be introduced by Yang Ping. Everyone is familiar with Yang Ping. In the medical field, he is now a legendary half-human, half-god. Anyway, the more he is passed on, the more legendary he becomes, especially among young doctors. It's like talking about him in an animation.

Looking at the experts at the table, Yang Ping said very honestly: "The method I proposed is neither a fantasy nor an attempt to be different, but has a sufficient theoretical basis. Since the cause of death from rabies is caused by damage to the nervous system, why can't we seize this point and protect the nervous system. Through drugs, the brain can enter a low-energy state, thereby effectively reducing the occurrence of rabies complications in the brain and reducing nervous system damage. At the same time, the patient's immune system continues to function. If during this period of time, the patient's immune system can produce enough anti-rabies virus antibodies, the virus can be eliminated. In other words, the patient is allowed to fake death in order to cheat the virus in an immune race."

"The target of the rabies virus is the brain. Usually, the rabies virus enters the human body, and the immune system fights bravely against it. As the battle goes on, the virus decapitates the brain, the general, and the war is naturally lost. In fact, if the general is not decapitated so quickly, the immune system may still be able to eliminate the virus. So we came up with a strategy to hide the general as soon as the battle starts and announce that the general has died in battle. Then the virus, which is good at decapitation, has no choice but to continue fighting the immune system. As the battle goes on, as long as enough time is given, the immune system may be able to eliminate the rabies virus. In the past, the immune system could not eliminate the rabies virus mainly because there was not enough time, or even if it had the upper hand, the general would always be decapitated in the end, and it had to be declared defeated."

This makes it easier to understand and the meeting seems less rigid. Since it is a new plan, everyone can discuss it in a relaxed manner.

Director Yuan has been thinking about this method these days. It is indeed very creative, but it has not been tested in animals or clinical trials. He directly uses the theory. However, this is also a special case. Since it is a 100% mortality rate, using a new method is to strive for a breakthrough. The worst thing to do is to maintain the status quo - 100% mortality rate. If he supported Yang Ping before because of Professor Su's face and Yang Ping's reputation, now after thinking about it for a few days, he is convinced. Regardless of whether this method is useful or not, at least it has achieved a breakthrough in theory and has not been stuck in the same circle.

The original method is definitely not working, but nothing new has come out, so we can only stick to the old method for the time being. If it really worked, there wouldn’t be a 100% mortality rate. In fact, the original method is no method.

"Professor Yang, I have been thinking about it for so many days, and what you said does make sense. To use the words of you young people, it is really a very creative idea. Although I have not done any experiments, I think there is a certain success rate." Director Yuan was not flattering, he was speaking the truth.

Director Luo of the ICU said: "I think that some things can be judged theoretically. Even without experiments, we are somewhat confident. I just listened to Professor Yang's explanation. At first, I didn't understand why such a new method was invented on the spur of the moment. But after listening to it, I was quite touched. Some things can indeed be understood without experiments. This new method really broadened my horizons. In fact, we have been doing many things this way all the time, regardless of whether the effect is good or not, and we have not reflected on it, or even come up with some ways to improve the effect."

What everyone said is the truth. Normally, most of our work is repetitive and we rarely think about innovation. After all, innovation comes at a price, and people without a certain level of curiosity will hardly be motivated to innovate.

While we were discussing, a doctoral student came in and said that the antibody titer of the latest virus had increased.

Increased? That means the disease has reached a turning point, which means the immune system has a great chance of eliminating the rabies virus. Yang Ping felt more confident.

This conference not only had senior experts participate in the discussion, but also gave young doctors an opportunity to join in the discussion. Everyone felt a sense of familiarity when seeing Yang Ping, and they spoke boldly. After all, they were all young people, and these doctors treated him as one of their own.

After the meeting, Yang Ping was about to go home, but Professor Su immediately called and told Yang Ping to go to his office quickly.

Why go to the office? My father-in-law is too busy today, so he prepared a lunch box and asked me to come over to eat. I hope my father-in-law won't ask me to stay for dinner every time in the future. Yang Ping was muttering as he walked towards Professor Su's office.

Seeing several guards in military uniforms in the corridor, he gave his name and the guards immediately took him to Professor Su's office.

Yang Ping was puzzled as to why there were guards guarding Professor Su's office.

After knocking on the door and entering, I saw a mighty man in military uniform sitting inside. He looked very similar to my father-in-law, and the flower on his shoulder showed that he was a general-level official.

"Come in quickly and call Fourth Uncle!"

"Fourth Uncle!"

Yang Ping shouted quickly.

The general stood up and patted Yang Ping on the shoulder: "You are Yang Ping. I have heard of you before I have seen you. You are very famous."

Yang Ping didn't know how to respond.

"You are just a silly boy. You only know how to smile foolishly. Why don't you sit down and chat with your uncle?" Professor Su said lovingly.

Fourth uncle? Which fourth uncle? Oh, Yang Ping remembered that among the four brothers of Professor Su, this fourth uncle was the only one he had never met. He had met the other three at Su Nanchen's birthday party. He only heard from Xiao Su that this fourth uncle was in the army.

"He performed surgeries on several of my old leaders. He is very famous." Su Qinghe smiled heartily.

Yang Ping's face turned red, and Professor Su said, "Young people only know how to perform surgery and can't speak. Don't mind it, Old Four."

"Second brother, you have a keen eye. This young man is no ordinary person. He is the youngest expert in the health care group. Several of my old leaders have praised him highly. Today I finally saw him in person."

"Professor Yang!"

"Call me Xiao Yang!"

"Look, you are so humble. My old leader always calls you Professor Yang, but I call you Xiao Yang. If I meet my old leader one day, I will definitely be criticized." Su Qinghe joked.

"He's a family member, so just call him Xiao Yang." Professor Su said with a smile.

Su Qinghe thought for a moment and said, "Okay, Xiao Yang, Professor Chang Qirui is in charge of a very important project now. If anything happens to him, the success of this project may be delayed by 5-10 years. We didn't expect something like this to happen. I just heard from your father that rabies has a % mortality rate, which is an unchangeable fact. But I heard that you are using a new method to treat it. Can you tell me how confident you are? I just want to understand the situation."

"It's hard to say because we've never used this method before. But judging from the current changes in the patient's condition, there is still hope. It's not a 100% certain death rate," Yang Ping replied.

The latest examination report just showed that the rabies virus antibody titer was elevated, which means that there is a certain success rate, and this success rate is quite high.

PS: I am a bit busy today, so the revision may not be careful. I will revise it tomorrow if there are any problems. Thank you!