I collect gold fingers in the heavens

Generally speaking, before a new drug goes on the market, it needs to conduct phase I, phase II, and phase III clinical trials.

Generally, the first-phase test is also called the clinical pharmacology and toxicological effect test period, which is a preliminary clinical pharmacology and human safety evaluation test for new drugs, including human tolerance tests and human pharmacokinetic determinations, that is, drug absorption. , distribution, metabolism, elimination, etc., to observe the safety of drugs.

Unlike other non-tumor drugs, new anti-tumor drugs usually need to select tumor patients as subjects due to their high cytotoxicity; the number of people in the second phase trial will increase, and further research on the applicable population, efficacy and safety of the drug; the third phase trial often Compared with the current best treatment model, only when the curative effect of the drug exceeds that of the existing better drugs can it become an effective new drug and be approved for marketing.

If the time is calculated from the first phase of the trial, it will take 5-10 years for the new drug to be approved for marketing, most of them will take 10 years, and some will even be longer, reaching 15 years.

After the drug is approved for marketing, Phase IV clinical trials are required.Phase IV clinical trials are also the clinical monitoring period, monitoring the efficacy of new drugs and the incidence and degree of adverse reactions.If the curative effect is unsatisfactory, or serious adverse reactions occur with a high incidence, the regulatory authorities will recall and withdraw the new drug from the market.

This is the time to market for new anti-tumor drugs.

In other words.

If patients with these advanced cancers wait more than ten years, they will have the opportunity to be prescribed [redikumab] from the doctor—if they can live to that time.

And unless the cancer is completely cured, patients with these advanced cancers will not live more than ten years later.

Most of them may not survive a year.

So the doctor's answer is unacceptable to them.

They strongly demand to get [Redikumumab]!
The doctors and the hospital had no choice but to comfort the patients and their families, saying that the drug [Redikumab] is still in the first phase of clinical trials, and the current medical data is scarce. Undecided, for the safety of patients' lives and property, we still have to wait until there are enough clinical trial data.

After all, the side effects of some drugs are not obvious, and it is not uncommon for drugs with side effects to be discovered after many years on the market.

For example, the former magic medicine—【Analgin】!
[Analgin] is an antipyretic and analgesic drug invented by the Germans. It was launched as an over-the-counter drug in 1922, and it was produced and launched in Huaguo in 1950.

[Analgin] is very popular all over the world because of its cheap price and great effect.

However, half a century after it was launched, all countries have found that it has too many side effects.

This drug will reduce neutrophils in the blood, which will lead to decreased immunity, increase the risk of infection, and may also cause autoimmune hemolysis, aplastic anemia, allergies and other problems, and even a large number of patients died.

Therefore, for safety considerations, the risk outweighs the benefit, so many countries around the world have banned or restricted the use of [Analgin].

This is the case with many western medicines on the market.

Side effects that were not found in clinical trials were discovered only after long-term large-scale use on the market.

Therefore, new words are often added in the adverse reaction column of the western medicine instructions.

In this regard, western medicine cannot be compared with traditional Chinese medicine.

In the instructions of traditional Chinese medicine, adverse reactions and contraindications only need to be written that they are not clear.

As long as [not yet clear], there will be no [side effects], it's perfect!

Some licorice tablets like a compound.

Although it is also cheap and effective as a cough medicine.

But the main ingredient that it works as an antitussive is opium powder.

This thing, if you eat too much, it can become addictive!Long-term continuous consumption will form drug dependence.

In addition, if people with high blood pressure take this medicine, there may be risks of increased blood pressure, hypokalemia, edema and other problems.

Forget it.

Don't say that.

Back to the topic.

Under normal conditions.

These concerns of oncologists are not without reason.

But that's for normal people.

These cancers are in the advanced stages, and they have lost surgical treatment and can only be treated conservatively. They are almost dying. If there is a glimmer of hope, they will never let it go.

So their reaction is bigger.

They dare not provoke [Xuanhu Technology], the [Miraculous Drug Research and Development Company] that controls their life and death.

Therefore, these patients and their families can only put pressure on doctors and hospitals, two [vulnerable groups] comparable to banks.

Hospitals are stressful.

at the same time.

[Redikumab]'s amazing effect on cancer has also spread in the society through the social relationship between cancer patients and attending doctors.

Following [Douyin]'s previous video [After taking the new anti-cancer drug, many patients with advanced cancer found no cancer cells in their bodies, and another terminal illness was overcome by humans], the entire public opinion was instantly detonated.

Countless people reposted and discussed it, and major social media reported it.

From this, many people know that there is a new anti-cancer drug that can effectively treat most cancers in Yue Provincial Cancer Hospital, and the effect is amazing.

Because of the high popularity, Yue Provincial Cancer Hospital had to come forward and explain that its hospital is assisting [Xuanhu Technology] in clinical trials of a new broad-spectrum anti-cancer drug, but because the trial time is short, the effect is still uncertain.

As soon as this statement came out, the popularity became even higher. It turned out to be true!
A large number of media reporters and family members of patients flocked to Yue Provincial Cancer Hospital.

Most of the family members of the patients are family members with advanced cancer, in order to find a hope.

The media reporters want to report in depth and learn more about relevant news.

The Yue Provincial Cancer Hospital was besieged and its normal work was severely disrupted.

Moreover.

In this experiment, the most accurate data is in the hands of [Xuanhu Technology].

If they can't find [Xuanhu Technology], they will only find [hospitals] for vulnerable groups.

The hospital had no choice but to reject the interview requests of major reporters.

But these uncrowned kings, of course, will not stop there, but the Eight Immortals cross the sea, each showing their magical powers.

Hospitals and doctors do not accept interviews, so they find patients who enter the experimental group.

Some patients in the experimental group who were on the verge of life and death wanted to be interviewed by reporters.

They hope that through reporters, they can put more pressure on the hospital and have a greater impact, so that they don't have to wait [more than ten years] to take this medicine before they die.

Although this drug has not undergone long-term clinical trials, it is not known what side effects it has.

However, these patients who are in the advanced stage of cancer and have no chance to join the [Redikimab] experimental group or have joined but have no effect will die.

What's the point of saying side effects to them?

The meaning is for the living.

The dead don't care.