As a mage, I just want to pursue the truth

Chapter 295
Since the advent of bio-storage technology, it is considered to contain the secret of electronic immortality.

In the two years since Huaguo took the lead in releasing the bio-storage server, in the newly released sci-fi works, many of them started from bio-storage technology and imagined that the human soul would be uploaded to the bio-storage server in the future.

In fact, souls and memories can indeed be uploaded, but this is not possible with biological storage technology.

And even if the soul and memory are uploaded, immortality cannot be achieved.

"Mr. Li, the results of the first batch of clinical trials are very good, even exceeding our expectations.

The compound composed of these five small molecules has an extremely good effect on adult CM proliferation and heart regeneration.

At the same time, it can play a certain role in preventing coronary artery blockage and precordial compression pain.

This is a clinical trial report, a phased report so far, you can take a look at it when you have time. "

After Wang Jinsong handed the report to Li Miaomiao, he left the other party's office.

In fact, the relevant processes can be completed in the internal office system, and the periodic reports and the phased results of the work are sent to Li Miaomiao through the corporate mailbox.

But in order to impress the leaders and at the same time explain how their work works.

Interviews are always more convincing than emails and can impress leaders more.

Especially now that there are so many pipelines in the research and development team of innovative drugs, only their new drugs have reached the stage of clinical trials.

No matter what kind of company you are in, you must be able to speak as well as do it. If you only know how to do it, you will not be promoted.

Even if it's just to get more resources for your subordinates and allocate fewer low performance appraisal indicators at the end of the year, you need to report to the leaders more.

As a returnee, Wang Jinsong suffered a few times because he didn't understand this truth.

So now even if you don't want to do this, you will do it.

Under normal circumstances, Zheng Li would not meet them, except at the annual meeting, Zheng Li would give a speech via remote video connection.

In addition, grassroots employees and even middle management have no chance to meet Zheng Li.

The only way they can contact Zheng Li is by email.

Every employee of Kechuangbiology can send emails to Zheng Li, and the employees of the chairman's secretariat will sort and process the emails.

Reply, forward to relevant people or show Zheng Li by email.

In Zheng Li's view, there is absolutely no need to set up a department like the Secretariat, and the artificial intelligence of the bio-cloud can perfectly handle these tasks.

In order not to look special, the secretariat was set up after the company grew.

Li Miaomiao is different from Zheng Li, middle-level employees can make an appointment to communicate with her alone in the internal system.

Li Miaomiao's secretary will arrange according to her wishes.

Li Miaomiao listened very enthusiastically to the communication with Wang Jinsong this time, because what the other party said was not boring, and she could clearly describe the work they did in a language she could understand.

This is not easy, because the cutting-edge field of biomedicine is too professional, and it will be a test of the reporter's skill to make it understood by laymen.

But this is also due to the improvement of Li Miaomiao's thinking ability.

If it were Li Miaomiao in front of the magic brain, it would be a bit difficult to understand.

Those who pay the most attention to the research and development progress of Kechuang Bio’s innovative drugs, in addition to the executives of Kechuang Bio, are the shareholders who hold the shares of Kechuang Bio.

They are even more concerned about the clinical trial effect of innovative drugs than the executives of Kechuang Bio who are not in charge of the innovative drug line.

"Does anyone know how the clinical trials of Kechuangbio's MSCS type I drugs are performing?
If the clinical trials of this drug perform well, then the market value of Kechuang Bio is worth going to a higher level.

Although Kechuang Bio was a leading company with a market value of trillions before, it actually relied heavily on its founder Zheng Li.

In terms of Zheng Li's age, he is only 25 years old, which is the golden age of scientific research.

At least 50 years before the age of 25.

However, I always feel that there is a risk in a scientific research enterprise that relies on one person.

And if Kechuangbio makes a breakthrough in the field of innovative drugs, it will prove that the research and development team of Kechuangbio is trustworthy, and it will add an insurance for the scientific research capabilities of Kechuangbio.

Whether it is from the official reply of the Secretary of the Board of Directors of Kechuang Bio, or the speeches of Kechuang Bio executives on different occasions, it can be seen that Zheng Li has almost never been involved in the development of innovative drugs.

The drugs that Kechuangbio put into the clinical stage this time are mainly for heart cell failure.

This is a field with a vast market, and it is a field where pharmaceutical giants from all over the world have invested a lot of resources to compete for it.

Although Pfizer has made rapid progress in research and development in this field in recent years, Kechuang Bio's innovative drugs still have merits.

First of all, this is a drug mixed with a variety of small molecules, and at the same time, the drug can regenerate cardiomyocytes.

According to the "Hua Guo Cardiovascular Health and Disease Report 2025" officially released by Hua Guo, the number of people with heart failure in my country alone was about 1000 million last year.

Once MSCS I is doing well clinically, what a huge market it is?

More important than this market is the success of Kechuangbio's R&D team. "

There is also a master behind Pfizer, which has led to the progress of their drug development far exceeding expectations.

In fact, American's R&D investment in the field of biomedicine has been increasing.

Especially after having mages, American invested half of the mages in the field of biomedicine.

Going back to innovative drugs, Kechuang Biotech chose the cardiovascular direction at first, and it was only for the purpose of exploration.

At that time, I never thought that this field could really produce any results.

Because there are too many competitors in this field, small molecule drugs have been screened many times, and it is difficult to make a breakthrough.

It's like you go to a river where countless gold diggers have panned for gold, and then you want to pan for gold. It is very difficult to pan for gold.

Unexpectedly, this seemingly most difficult field was the first to produce results and entered the stage of clinical trials.

In recent years, due to the proliferation of unhealthy diet, lack of physical activity, staying up late and smoking, etc., the absolute number of cardiovascular patients in Huaguo has continued to rise.

The direction chosen by Kechuangbio has a broad market.

Of course, because there are too many patients in this field, it is inevitable that they will enter the collective buying.

It's just the difference of time.

"Hello, Dong Zheng, the following is the phase I clinical trial report on MSCS type I myocardial regeneration drugs.

Myocardial infarction results in massive loss of functional cardiomyocytes and is one of the leading causes of human death worldwide.

Although drug therapy, thrombolysis, coronary artery stent implantation and coronary artery bypass grafting have been used clinically to treat myocardial infarction and improve the survival rate of patients.

However, these methods cannot fundamentally repair the damaged heart and restore heart function.

Stem cell transplantation is considered a promising approach for the treatment of myocardial infarction.

Stem cell transplantation has made significant progress in preclinical and clinical research in recent years.

Stem cell candidates mainly include two categories: pluripotent stem cells and their derivatives, adult stem cells including hematopoietic stem cells and mesenchymal stem cells.

Mesenchymal stem cells are mesoderm-derived pluripotent stromal cells present in embryonic and adult tissues with the capacity for self-renewal, immune privilege, immunoregulation, and low tumorigenicity.

To date, mesenchymal stem cells have been the most commonly used cell type for therapy in clinical trials due to safety, multidifferentiation potential, nutritional activity, immunomodulatory properties, and abundant donor source.

The MSCS type I myocardial regeneration drug we developed can effectively induce the expression of mesenchymal stem cells in clinical trials.

At the same time, because the mesenchymal stem cells are the patient's own, it shows a better effect than traditional mesenchymal stem cell transplantation.

Left ventricular systolic function in patients after bone marrow mesenchymal stem cell transplantation only increased by 3-10%.

Implanted cells do not survive for long.In fact, within 24 hours after transplantation, only about 3% of MSCs appeared in the border area of ​​infarcted myocardium, and less than 1% of MSCs survived for more than one week [5].

More importantly, it is difficult for mesenchymal stem cells to differentiate into cardiomyocytes.

By using MSCS I drugs, the systolic function of the left ventricle of the patients increased by 23%-37%.At the same time, after one week of continuous administration, more than 5% of bone marrow mesenchymal stem cells appeared in the border area of ​​the infarcted myocardium.

At present, the specific data on the differentiation of mesenchymal stem cells into cardiomyocytes are still being observed.

Critical steps of the cell therapy program, such as in vitro donor selection expansion, survival in the hostile transplant microenvironment, migration, differentiation, and paracrine function were fully optimized.

According to the existing clinical experiment data, we can conclude that MSCS type I drugs have shown much superior therapeutic effect than traditional stem cell transplantation.

Attached is a detailed phased clinical trial report."

It has been a month since Zheng Li finished reading this report, and he was very happy at CERN.

Especially after being able to conduct research exactly as one wishes.

The understanding of the soul is much deeper than before.

"Alan, congratulations, there are new results recently, and the sensational effect of this result is no less than the previous paper."

Kate tried to hint to Zheng Li many times, but did not get the answer she wanted.

Zheng Li didn't show any affection for men and women at all, Zheng Li would only say a few more words when Kate talked about research-related matters.

"Actually, people have been speculating about this discovery."

Kate was a little depressed in her heart, because the other party was always able to say that a great discovery was worthless.

There is always a kind of opponent who is pretending to be aggressive, but there is no sign of acting aggressive from his face.

Kate said speechlessly: "If this is nothing, then the other researchers in CERN have nothing to achieve.

Including all the papers I have published since my Ph.D. graduation to today are not worth mentioning. "

Kate, who has been a top student since she was a child, has seen many Nobel Prize winners at CERN.

In Kate's eyes, Zheng Liyu has an extremely keen sense of smell and unlimited energy at the same time.

Other scientists with a keen sense of smell usually need to rest for a long time after studying a problem.

Like Zheng Li, who has just proved the existence of high-dimensional space, and then devoted himself to the research of the next topic, and successfully solved it, Kate has never seen it before.

What scientific research compares is not the ability to solve problems, but the ability to solve problems.

Of course, there are some people who can make scientific research the same as doing a problem, but that kind of scientific research is not very meaningful.

The utilitarian research of publishing paper for the sake of publishing paper can only be said to be seen by the benevolent.

"I knew before that you could win this year's Nobel Prize, and now it seems that you are very likely to enjoy this year's Nobel Prize."

"We have always suspected that even when intelligent life is alive, soul particles are escaping.

But guesswork is a long way from being proven.

You just covered this distance.

Goldbach conjectured that no one can falsify it, and when it is finally proven, it is not a trivial matter. "

When Zheng Li used CERN equipment to do private work for his own research, he threw out some incidental research results by the way.

The Europa League is delighted with Zheng Li's discovery and believes that his discovery is of inestimable value.

When they were discussing internally, they were all feeling that Higgs had an amazing vision, and the chosen successor was even better than they expected.

Allen is only about 40 years old, and with the addition of the magic brain, it means that he can be in charge of CERN for the next 40 years.

Different social organizations have different functions. The heads of top scientific research institutions generally do not change, and it is best to be stable for a long time.

They were melancholy because similar guesses had already been submitted in the magic forum, and if the guesses were confirmed and then submitted, they would not be able to obtain magic coins again.

"Well, this is the past tense, we need to look forward." Zheng Li said.

Kate asked: "Would you like to travel and relax?
We can go to the beach, in summer we should go to the beach to travel and relax!

Life should not only be work. I feel that you are too tight and need a breathing time. "

Zheng Li thought: Are you crazy? I have only been the head of CERN for less than half a year, and you let me rest?
There are still many things I want to do, how can I have time to travel, and what is there to see on the beach, is it more interesting to have particle motion images?

I watch the sea on Clark Island every day, and I have long been tired of watching it.

"No, no, you misunderstood, I didn't collapse very tightly, in fact, I was in a very good state, and it was rare to live so full.

If you need a break, I'll give you a leave of absence. "

In fact, the contradiction between these lies in whether you are enjoying it. If work can bring you happiness, you will not be particularly sensitive to vacations.

Generally, those who are sensitive to vacations are migrant workers. Everyone works for income.

The boss is not sensitive to vacations at all. Entrepreneurs often publicize that they are open all year round.Their year-round work is totally different from that of a worker.

First of all, they work for themselves and have a natural self-motivation. Watching a project or enterprise go from zero to one, the sense of accomplishment is incomparable to the workers.

The other is that they have the right to control time, which can optimize the distribution of personal energy to the greatest extent and achieve the greatest degree of joy.

After speaking, Kate fell into silence, and she held her forehead and thought: No wonder Alan is 40 years old and still not married.

(End of this chapter)