This doctor has a system

Chapter 559 622. Bitten by a Pig

"Why is it inappropriate? I think it's absolutely suitable!" Director Bu picked up the last piece of braised pork and put it into his mouth.

After eating and drinking, everyone talked about this patient again.

"It's very strange." Bu Zhengyang wondered, "I checked so many items, but the results were all negative. Who can I complain to?"

Long-term fever will undoubtedly cause great damage to the patient's physical condition. Huang Huili's anemia, jaundice, and fatigue are all specific manifestations.

If the cause of the disease cannot be found, then as time goes by, she is likely to develop more serious symptoms or even die.

Ward 55
"Are you eating?" Gao Feng asked with a smile.

"Hello, Director Gao." Huang Huili was in good spirits and finished a box of braised pork.

"I came here just to ask if you had any abnormalities during the period before you became ill?" Gao Feng asked, "Think about it carefully."

"It seems not." Huang Huili thought for a while and replied, "I just work in the farm all day, nothing special."

"Have you ever been away from home?"

"No."

"Has anyone in the family been away from home and returned?"

"nor."

"Did you have any wounds during that time? Were you bitten by anything?"

"I haven't been bitten." Huang Huili replied. As for wounds, she did have some bumps and bruises because she worked a lot.

These questions had actually been asked before, but Gao Feng still felt very disappointed. He spoke a few brief words to the patient and his family, and then prepared to leave.

But just as he reached the door, the family member's uncertain voice rang out: "Have you been bitten by a pig before?"

"What?" Gao Feng immediately turned around and walked back, "Have you ever been bitten by a pig?" This is quite rare.

"There was one time, a long time ago." Huang Huili thought for a long time before she remembered, "But it healed very quickly. Look, there is no scar left." She said, pointing to a shallow mark.

What disease will you get if you are bitten by a pig? Gao Feng's CPU started to work frantically.

Pigs are rodents and can carry a variety of pathogens on their teeth, which can easily lead to wound infection;

Because there are many bacteria in teeth, if the wound is deep and the skin bleeds, the patient will experience symptoms such as swelling and pain. In severe cases, it can lead to necrosis of local soft tissues such as muscles.

The patient had no symptoms in this regard.

Pigs may also carry and spread the rabies virus. The Technical Guidelines for Rabies Prevention and Control issued by my country's Center for Disease Control and Prevention clearly state that all mammals can contract rabies.

Therefore, after being bitten by a pig, rabies may also be transmitted to humans. It is necessary to get the rabies vaccine in time. The best time is within 24 hours after the injury, and it is best not to exceed 48 hours.

But in reality, the probability of domestic pigs carrying rabies virus is almost zero, and there has always been controversy over whether to vaccinate them or not.

But no matter what, the patient definitely does not have rabies.

Because there are many bacteria in teeth, if the wound is deep and the skin bleeds, the patient will experience symptoms such as swelling and pain. In severe cases, it can lead to necrosis of local soft tissues such as muscles.

There is a disease with a relatively high incidence rate, streptococcal disease, which is a general term for various zoonotic diseases caused by β-hemolytic streptococci.

The clinical manifestations of streptococcal disease vary, but the main symptoms are septicemia and purulent infection. Streptococcus suis is a common bacterial disease in pig farms. After infection, it can cause symptoms such as meningitis, arthritis, and septicemia in sick pigs.

But if it was a streptococcal infection, Huang Huili would not have come to the provincial hospital, and those antibiotics can cover this pathogen. This situation can be ruled out.

Gao Feng sat in the office and thought for a long time, but still had no clue. Li Youliang brought a cup of tea over, he took a sip and breathed a sigh of relief.

"What is this? It tastes pretty special."

"Scented tea, I can't tell you what kind of tea it is." Li Youliang poured him another cup.

After resting for a while, Gao Feng carefully went through the patient's medical records again to make sure he had not missed any information.

It can cause liver enlargement, anemia, jaundice, and fever. It is very likely to be a disease shared by humans and pigs. By the way, sideroblasts can be seen in bone marrow biopsy.
The CPU is running wild again
Ten minutes later, his eyes lit up, as if there was a disease: swine eperythrozoonosis.

Eperythrozoonosis is a zoonotic infectious disease caused by Eperythrozoon parasitizing on the surface of red blood cells, plasma and bone marrow of various animals and humans. Human Eperythrozoonosis can have a variety of clinical manifestations, mainly fever, fatigue, sweating, lethargy and other symptoms. In severe cases, there may be anemia, jaundice, liver and spleen enlargement, lymph node enlargement in different parts, etc.

The disease is not very rare in my country. The infection rates vary greatly across the country and are mainly concentrated in agricultural and pastoral areas. The main population affected are workers engaged in poultry and livestock food processing, animal breeders, and veterinarians.

There was a reason why Huang Huili was diagnosed with myelodysplastic syndrome at that time.

Eperythrozoon suis is a type of unicellular protozoa, a parasite. Some people also believe that it is a member of the Rickettsiales order and belongs to the genus Eperythrozoon. This organism easily adheres to the surface of human red blood cells but does not invade red blood cells, and often causes infectious anemia in pigs.

It also provides iron to host cells, causing large amounts of iron to accumulate in red blood cells, which may explain why bone marrow biopsy results at local hospitals showed the presence of sideroblasts.

The diagnosis of eperythrozoonosis mainly relies on peripheral blood smear and bone marrow cell smear, but because eperythrozoons can cause hemolysis, they are difficult to detect in routine single-cell thin-layer blood smears.

Without the support of epidemiological history or clear marking and reminder from clinicians, it is very easy for laboratory doctors to overlook it when performing smear tests.

Bu Zhengyang immediately contacted the laboratory, ordered a thick blood smear examination, and noted the suspicion of eperythrozoonosis.

The next day, everyone eagerly waited for the results of the thick blood smear: Erythrozoons were visible in the red blood cells.

At this point, the cause of Huang Huili's illness was finally found out.

This is also related to the region. The breeding industry in State Z is not very developed, and not many people suffer from this disease. There may be only a few sporadic reports every year, and many doctors have never seen similar patients.

If she were placed in some areas where animal husbandry is the pillar industry, Huang Huili might not have suffered so much.

The next step is treatment. Eperythrozoon is sensitive to tetracyclines and aminoglycoside antibiotics. In addition, levofloxacin is also effective.

This is also the reason why the patient had not had a fever for a period of time before. She was receiving an infusion of levofloxacin at that time, but due to insufficient treatment course, the disease recurred.

"My condition is so serious, why are my pigs fine?" Huang Huili was very puzzled.

“Simply because pigs tend to get treated more promptly.”

It's quite funny to say, but after pigs are infected with this disease, their physical condition will deteriorate, they will suffer from anemia, and their intestinal and respiratory infections will increase; the daily weight gain of fattening pigs will decrease, and they will suffer from acute hemolytic anemia; and the production performance of sows will decrease.

But usually at this time, the owner will use drugs such as tetracycline, oxytetracycline and chlortetracycline, and use them for a relatively long time.
So the pigs are fine, but the humans can't stand it.

After using doxycycline for one week, Huang Huili's body temperature was finally under control.

"Continue to take the medicine for 6 weeks after you go back," Mao Wen instructed her, "Go to the hospital regularly to check your blood routine and liver and kidney function." Six weeks later, Mao Wen followed up with the patient by phone.

"It's all right now! I'm fine now." Huang Huili was very happy. "Thank you doctor for your concern."

"That's great." After hanging up the phone, he was very happy for the patient, but also a little regretful that he would never be able to eat such delicious braised pork again. +
Fengxin Technology Laboratory

"This milk tea is so damn undrinkable!" Wang Liang was very angry. He only had one cup in several days. It was really annoying.

Thinking of this, he immediately took out his phone and gave it a 3-star rating: "It tastes good. My grandfather told me in a dream that he wanted to drink your milk tea by name, otherwise he would take it away. He said this place is very good, and he will bring the chef who makes milk tea with him next time."

The boss who was counting the bills soon saw this comment and was immediately moved to tears: "Thank you for your affirmation, my dear. We will work harder to serve you in the future! At the same time, I am also happy for your grandfather to have such a filial grandson. I hope you and grandpa can reunite soon to relieve the pain of missing him."

Damn it! Wang Liang was almost mad. He slammed the table hard, startling his colleague Yang Tao who was adding reagents.

"What the hell is wrong with you!" Yang Tao was very dissatisfied, "You made me add the wrong bottle!" He had no choice but to take another base.

This substrate with the wrong reagent added stays quietly on the table. If nothing unexpected happens, it will be thrown away at the end of the get off work day.

"Honey, I miss you. I'm wearing black stockings today." Yang Tao received a call from his girlfriend when he was about to get off work.

"Right there!" He rushed out immediately.

"Fuck! You're leaving now?" Wang Liang was shocked. "With so many specimens, who are you going to ask to help you with that?"

"Dad, help me!" Yang Tao shouted at him.

I don't have a son like you, Wang Liang thought, but when he saw the other person running away, he could only walk over helplessly. These substrates were added with different doses of reaction reagents. The next step was to put them in a constant temperature box and let them stand for 48 hours before centrifugation.
He labeled the bottles one by one in chronological order. When it was the last bottle's turn, Wang Liang was a little confused. Why was there no record of this bottle?

Waste liquid?

He picked it up and prepared to throw it away, but when he stretched out his hand, he hesitated. Forget it, he decided to ask Yang Tao later.

Wang Liang pasted a blank barcode on it and then closed the door of the laboratory.

Damn Yang Tao, he made me work overtime for two full hours!

Two days passed quickly. Yang Tao and his colleagues took out the specimens one by one from the incubator. Today they were going to subject these things to high-speed centrifugation. The separated cells would be purified a second time, hoping to discover something if they were lucky enough.

"Brother Liang, come on! Two people really can't finish it."

"Call me dad. Forget it, just treat me to a meal!"

"No problem." Yang Tao quickly agreed.

The three of them had a simple meal and then began the boring specimen processing work. Many scientific research workers don't like doing this kind of work, which is mechanical and repetitive. You can say it is simple, but you can't make mistakes when operating it.

Another thing is that once you start, you generally cannot stop without special reasons. Otherwise, you will have to do the preparatory work all over again.

When Wang Liang worked overtime in the past, he had to wear diapers in order to avoid going to the toilet.

The three of them chatted with each other at first, but then fell silent, wanting to quickly deal with the specimens.

"Taozi, what's up with this blank label?"

"I don't know." Yang Tao replied, "It should be Brother Liang who posted it."

"The tail you left was because I didn't know what it was, so I put a blank label on it." Wang Liang said after thinking for a while.

"Oh, now I remember, it was a bottle of waste liquid. I added the wrong reagent." Yang Tao replied, "Throw it away."

When he heard about throwing it away, Wang Liang subconsciously looked up and said, "This one is bluish in color, and looks a little different from this batch..."

"Then why don't you just stop talking nonsense." Yang Tao said with a smile, "I already said I added the wrong reagent."

……

The three of them worked until 11: pm, when they finally finished centrifuging the specimens. After changing his clothes, Wang Liang felt exhausted.

"I'm old. I didn't feel this way before."

"It's mainly because we haven't worked overtime much recently, and we can't stand the intensity." Yang Tao brought a bottle of mineral water to the two of them. "Look at those small islanders, they leave at the appointed time. Isn't it said that overtime is also serious in island countries?"

"Who cares?" Wang Liang replied. Sometimes he really wanted to visit these small countries around.

I'm a little curious about whether Tokyo is hot or not.

At about 2 a.m., a dark figure appeared outside the laboratory. Wang Liang yawned and swiped the door card to open the door.

After he came in, he went straight to the trash can and quickly pulled out a test tube. The solution inside emitted a light blue glow under the light.

Luck is a mysterious thing, it seems to be everywhere and elusive. But sometimes it will inexplicably befall some people, some people are unaware, but some people touch this mysterious energy.

Wang Liang actually wanted to come earlier, but Liu Fang disagreed.

"I've been waiting for you till this late! Do you really think I have a good temper? Huh?!"

"I'll give you five minutes, now go take a shower!"

After all the trouble, the girlfriend was satisfied and Brother Liang's legs became weak.

Why not? Wang Liang advised himself, it was just a specimen with the wrong reagent...

But when I was lying in bed, a light blue light would flash across my mind from time to time.

I'm really impressed! He sat up from the bed.

"You're sick in the brain!" Liu Fang fell asleep.

Wang Liang wiped the surface of the test tube carefully and placed it in the incubator. He also put a label on it: Wang Liang, do not throw it away.

After doing all this, Wang Liang inexplicably felt a sense of joy in his heart, and the fatigue in his body was reduced a lot.

How strange!

After he went back, he fell asleep.

(End of this chapter)