top student at medical school
Chapter 819 has been optimized and approved; the clinical research project has begun!
The comprehensive testing center was expanded from the original animal testing laboratory!
After Hu Qingyuan drove into the parking lot, Yao Guang probably received a call or message from the security guard at the entrance and immediately dialed Fang Ziye's number.
"Professor Fang, have you arrived at the testing center yet?" Yao Guang asked hurriedly.
"Director Nie and I are waiting for you in the instrument testing room."
The development of the bridging electrode was initially a collaboration between Fang Ziye and Nie Mingxian, but some problems arose after the application was submitted for approval.
Fang Ziye immediately consulted Yao Guang, the chief engineer of Guangbai Group. Yao Guang was naturally very interested in this new thing called bridging electrode and immediately flew back to Wuhan.
I've stayed until today.
"Okay, Chief Engineer Yao, I'll be there soon. I'm parking now and should be there in about twenty minutes."
"Have the expert team responsible for the preliminary evaluation of the project been arranged?" Fang Ziye asked.
Bridging electrodes are entirely new devices, and spinal cord injury is a completely new disease and treatment topic.
The newer something is, and the more significant its impact, the more cautious we should be.
Even though it's just the beginning of a clinical research project, the Ministry of Science and Technology and the National Natural Science Foundation of China attach great importance to it and have specially dispatched an expert team to stay for a period of time.
The purpose is threefold: first, to examine the preliminary research preparations of Fang Ziye's team; second, to assess whether they possess the qualifications to conduct clinical research; and third, to evaluate the safety and ethical compliance of the experiment.
Of course, another purpose is to fill in the gaps in this research.
Even a fool could see the importance of this topic in medicine. It's an area that allows China to stand out and lead in the medical field, so it's impossible for us not to pay attention to it.
Even if it is only a small branch of the broader field of medicine.
"I have received a message from Director Deng saying that everything has been settled. Vice Principal Yuan Yufeng and Dean Wang Xinghuan have both personally gone out to help, so there will be no problem."
“Professor Fang, come here first. Let’s check it carefully again. The issues raised after our project was submitted for approval still need to be reviewed a fourth time,” Yao Guang said.
"Okay, sure!" Fang Ziye agreed.
This matter concerns the progress of the spinal cord injury research project, so Fang Ziye certainly cannot delay it. Moreover, starting tomorrow, the expert team will be stationed at the comprehensive testing center to conduct a full-scale investigation.
The expert team assembled this time includes academicians from related fields such as orthopedics, neurosurgery, neurology, and spinal surgery.
There are also nationally renowned scholars and important leaders within the National Natural Science Foundation of China...
Scientific research is Fang Ziye's research task and is considered a private matter; it should not affect the outpatient clinic.
It's only natural that Fang Ziye would choose not to work overtime at such a crucial juncture.
After quickly stopping the car, Fang Ziye and Hu Qingyuan got out quickly.
Hu Qingyuan, carrying his backpack, said with his Adam's apple bobbing, "Master, today is the last review, there shouldn't be any special problems."
"Li Qixi, whom you sent to follow me, wants to come over and observe from a distance. What do you think?"
"She won't disturb the test review, and she's already taken a taxi to the door."
"After nearly a month of learning, she also understood the basic rules and knowledge of the laboratory..."
Hu Qingyuan said, "Of course, Master, if you don't agree, I'll just let her sit in a nearby coffee shop!"
"Personally, I think Li Qixi has some talent and ambition. It's only natural that she wanted to see the high-level scenes after she came into contact with our research group!"
Fang Ziye took a deep breath, his pace unwavering: "She can't come!"
“For this thing, Jiehan, my master Yuan Weihong has been in solitary confinement for almost a week, and you and I have been in solitary confinement for most of the past week.”
"Professor Liao Jia, Brother Nie Mingxian, Song Yi, and Brother Dong Ning have been practically living in the experimental zone for the past two weeks."
"No irrelevant personnel or variables are allowed in today's testing area."
"It's only because your master is so easygoing that we would have gone into seclusion for a whole month if we wanted to pay more attention to this topic."
Hu Qingyuan immediately replied, "Okay, Master, I'll send a message to Li Qixi and tell her to go and rest."
"Let me explain a bit more. You can come up with your own reasons. I don't have time," Fang Ziye said.
Soon, the two took the elevator to the third-floor equipment testing area.
Yao Guang strode over: "Professor Fang, after improvements, the conductivity is now up to standard. Under analog range voltage, the electrodes will no longer amplify the current, but will only maintain a very stable level."
"These are data."
"Professor Zheng from the Department of Neurology at Huashan Hospital truly lives up to his reputation as a top professor in the field; he gave away such crucial data so readily!"
Fang Ziye nodded: "Yes, I thought I would have to do a lot of explaining."
"The world is vast, and there are countless talents. It is impossible for us to be knowledgeable in all aspects and blind spots of knowledge, especially the unknown."
"There are too many directions, and too many complicated details to pay attention to."
"I'll need to ask you for advice more often in the future."
"However, the data for this project has not been released, and I don't know how the other professors' projects are progressing."
Fang Ziye continued, "But this time, the project was not subject to blind review, which was somewhat unexpected."
Yao Guangze said, "Professor Fang, blind review is for ordinary research projects. How could your project be sent for blind review? It's all done under real names."
"The higher-ups were afraid that someone would protect you, but they were even more afraid that someone would deliberately target you! This caused the project to be stillborn."
"In any case, Professor Fang, you now have the backing of Wuhan University, so other blind review experts won't dare to act recklessly."
"That's all the data," Yao Guang emphasized as he spoke.
Fang Ziye nodded. As he read carefully, he noticed that Nie Mingxian was sitting with his eyes closed, resting. His dark circles and eye bags were quite severe.
Fang Ziye moved closer and said, "Brother Nie, you've worked hard. Once we're done with today, we can take a break."
Play hard during big exams, play lightly during small exams.
If you prepare well before the exam, you can approach it with a relaxed mindset, and life or death won't matter much.
Nie Mingxian said, "It's tough. Everyone's working hard, including you."
"I am currently temporarily away from clinical work. The surgical ward has just moved to Seoul and has not yet returned to normal operation. The number of surgeries and patients is low."
"Otherwise, I wouldn't have so much free time."
“However, my master really can’t come,” Nie Mingxian explained.
Fang Ziye said, "I am already very grateful that Professor Li can take the time to give me a lot of valuable advice. He is now the dean of the branch hospital and the head of the surgical group. He has a lot of things to deal with."
"Even if Teacher Li were really willing to help, I couldn't accept it."
Professor Li Yongjun truly deserves his reputation as a leading expert in medical device improvement; his advice was invaluable.
"These data are sufficient. Previously, we only considered the stability of the current, but we overlooked the possibility that the local current might be amplified after passing through the electrodes."
"Poor electrical conductivity can damage the broken connection ends!"
"Our animal experiments are not long-term. If irreversible damage occurs over time, then we will be in big trouble."
"Fortunately, the members of the expert team this time were capable and meticulous, and their expertise covered a wide range of topics."
Even the most meticulous plans can have flaws...
The knowledge related to electrical conductivity difference belongs to the field of physics, but Fang Ziye cannot fully understand which specific branch it falls under.
However, the National Natural Science Foundation of China can provide relevant experts.
Moreover, this time, the secondary optimization of the needle electrode was carried out by a master of materials science, an academician, who personally came to help and guide the process for several days.
This experience also helped Fang Ziye to calm down.
I learned something: many hands make light work. Even if one person is made of iron, how many nails can they hammer?
Breaking the global deadlock and accomplishing groundbreaking achievements is no easy task.
“Let’s try it again,” Fang Ziye said.
"..."
About three hours later, another batch of experimental data was produced.
Fang Ziye, Nie Mingxian, Yao Guang, Hu Qingyuan and others carefully crawled over to examine the area, and then nodded repeatedly.
Suddenly, someone burst in: "How's it going? Have the results of the last set of experiments before the review come out yet?"
It was Liao Jia.
Fang Ziye turned around upon hearing this, slightly taken aback: "Brother Liao, isn't your wife quite far along in her pregnancy?"
"Her mother came to take care of her."
“When I went back to be with her, I was also very uneasy. She knows the importance of the project and is very curious about its progress. She’s currently waiting to see what happens.” “I was assigned to be a reporter.” Liao Jia, wearing protective clothing and gloves, approached as she did so.
There was a lot of data, and Liao Jia couldn't examine it all in detail in a short time.
"Just announce the results directly..." Liao Jia said simply.
“It’s great!” Fang Ziye said confidently.
"It's alright, that scared me to death." Liao Jia breathed a sigh of relief.
"When I saw the review receipt, I was really nervous. It would be such a shame if something I had worked so hard on was stopped because of this."
"Luckily, Ziye, you're really capable; you managed to bring in so many outside helpers!" Liao Jia patted his chest.
This project has been going on for quite a while.
Fang Ziye said, "It's not that I'm the one who's capable, it's that the leaders above are capable, okay?"
Liao Jia chuckled and said, "Most people and most professors can get by with social niceties, but truly top talents should not be underestimated!"
"It's mainly because you're outstanding, Ziye. Otherwise, how could an average professor be assigned such a high-caliber team?"
"So, are we just waiting for the mini-test tomorrow?"
"Okay! This is the last round of tests before clinical trials. After the tests, we should be able to get approval and officially begin in mid-June."
"Although it's half a month later than we expected, it's still within the normal progress," Fang Ziye said.
"I will have another surgery tomorrow, Wednesday. I'll have to trouble you all then."
Nie Mingxian and Liao Jia said in unison, "How can you describe something as arduous when it comes to showing off and putting on airs?"
In high spirits, Nie Mingxian and his companion pushed the car to its maximum speed, and suddenly the color changed.
And it's very direct.
"Hu Qingyuan, what time is it?"
"It's 11:30," Hu Qingyuan replied.
"Let's go back. That's all we can do for today. We can resume normal operations and display the data tomorrow."
“I’ll perform the animal manipulation again the day after tomorrow!” Fang Ziye said.
"Okay, Master, you can go back now. I still need to talk to Brother Song Yi. We had an appointment beforehand."
"His progress is similar to the progress of my experiment at the Enshi Sanatorium; it's stalled a bit," Hu Qingyuan said with a wry smile.
"We can comfort each other and stick together for warmth."
Hearing Hu Qingyuan's complaints, Nie Mingxian pursed his lips and said, "You know how important Song Yi's basic research is. The more difficult and impactful the research is, the longer the time and effort required."
"If only we could truly pinpoint, characterize, and quantify neural potentials!"
"Even if I can't win a Nobel Prize like Einthoven, it will still be of great significance."
In 1885, Dutch physiologist W. Einthoven first recorded electrocardiogram waveforms from the body surface. In 1924, Einthoven was awarded the Nobel Prize in Physiology or Medicine!
This is groundbreaking!
Liao Jiadao: "In 2000, Arvid Carlsson, Paul Greengard, and Eric R. Kandel won the Nobel Prize for their discovery of signal transduction in the nervous system."
"In 1981, Roger W. Sperry, for his discovery of the functional specialization of the cerebral hemispheres, and David H. Hubel and Torsten N. Wiesel, for their discovery of information processing in the visual system, jointly won the Nobel Prize."
"1944: Joseph Erlanger and Herbert Spencer Gasser were awarded the Nobel Prize for their discovery of differences in electrical signal conduction velocity and function among different nerve fiber subtypes."
"Statistically speaking, neuroelectrophysiology is a prolific field for Nobel Prizes."
Fang Ziye shook his head and said, "We probably wouldn't dare to covet something that high."
"You think you can win a Nobel Prize for the neurophysiological activity of just one area of the spinal cord? You're dreaming!"
The Nobel Prize in Physiology or Medicine is awarded only to those who have made significant contributions to basic medicine and its theories.
No matter how advanced surgical techniques become, they will never be awarded a Nobel Prize because they will soon be obsolete.
Only fundamental theories can have an impact for hundreds of years or even longer!
……
When Fang Ziye came out of the testing center, he found that Li Qixi was still waiting. However, the coffee shop was already closed, and she was sitting obediently reading a book in the security room.
Fang Ziye saw her while driving, but he didn't greet her or bother her.
Fang Ziye quite admired Li Qixi's personality.
Putting aside gender factors, someone who works so hard, is so ambitious, has ideas and talent, it would be hard for her not to succeed given the opportunity.
Perhaps I will be her opportunity.
Of course, she is currently under Fang Ziye's evaluation!
A few days passed in the blink of an eye, and Fang Ziye's surgical categories in clinical practice remained unchanged!
I'm incredibly busy every day. During the day, I'm performing surgeries, and at night, I'm either making minor adjustments to the research project in the experimental zone or going out to accompany the expert team that came down.
While there were certainly interpersonal interactions during the accompaniment, Fang Ziye found that there wasn't much of a personal exchange; the conversations revolved more around professional matters.
Perhaps it was because Fang Ziye was young, or perhaps it was because the topic was indeed very important, but the several big names who came each offered their own ideas for Fang Ziye's reference.
Unlike that professor from the China-Japan Friendship Hospital, he did not try to get involved, nor did he use his reputation to intimidate others!
Fang Ziye then understood that people who truly understand academia and scientific research have no shortage of research results.
Although the research projects I lead are not particularly significant, the research output is still very fruitful, and I don't envy or feel jealous of other people's achievements.
This is confidence!
The same applies to Fang Ziye.
On the last day of the college entrance examination, Fang Ziye personally came to the high-speed rail station to see him off: "Professor Zheng, I haven't mentioned it before, but I still want to express my sincere gratitude for your generosity in private."
"Your willingness to provide your confidential research data at such a critical time is of vital importance to the smooth passage of our project through the preliminary review."
Professor Zheng comes from Huashan Hospital, whose neurology department is second only to Tiantan Hospital in Beijing, making it one of the top three.
Professor Zheng is not tall, only 1.6 meters, but for him, small is good: "Professor Fang, I'm relieved that the data I provided didn't cause you any trouble."
“I have been studying spinal cord injury for nearly 20 years, and the progress so far has been quite limited. I never expected that you, Professor Fang, could find a new path and take a surgical approach.”
"This is a blessing for patients with spinal cord injuries!"
"However, I do hope that, if the opportunity arises, Professor Fang might want to learn about brain-computer interfaces and the transduction of neural signals. That would be a good idea."
"However, judging from the current situation, Professor Fang, your research topic may be superior."
Fang Ziye quickly replied, "Professor Zheng, you are knowledgeable; different paths lead to the same goal."
"There is no such thing as winning or losing. As long as the goal can be achieved, it is a good idea."
"Until a final conclusion is reached, no one knows which is better. Only with the passage of time will we know which is slightly better."
"I have carefully read many papers on signal transduction and brain-computer interface chips, and I will also consider combining them with surgery in the future."
"I hope that if I ever need your help, Professor Zheng, you will be willing to offer your guidance!"
Professor Zheng laughed and extended his hand: "Professor Fang, it's good to love learning, but being too modest is a bit hypocritical."
"Professor Fang may be young, but his speech, knowledge, thinking and ideas are all extraordinary. Although there is an age gap between us, we are already exchanging ideas at the same level in scientific research."
"Please don't use the word 'ask for advice' any further!"
"If I have any questions in the future, I will ask you directly. Professor Fang, if it's convenient for you, please don't keep anything from me!"
In any relationship between two people, as long as there is inequality, someone will always be accommodating.
Professor Zheng discovered that Fang Ziye's research level did not require him to be backward compatible; this was the essence of equal communication.
At this point, everyone's thirst for knowledge is very strong.
Fame, fortune, and social standing are no longer so important; the thirst for knowledge is what people are pursuing.
"Professor Zheng, see you next time. I believe we will definitely meet again next time," Fang Ziye said.
Upon hearing this, Professor Zheng thought for a moment and said, "Professor Fang, since you've put it that way, why don't you pay a membership fee and join our academic conferences in the field of neuroscience?"
"There will be more time and opportunities to communicate then... I can write a letter of recommendation for you."
“Okay!” Fang Ziye nodded.
"Okay, it's settled then. I need to catch the high-speed train." Professor Zheng turned around gracefully and entered the high-speed train station.
Fang Ziye waved goodbye, and only after Professor Zheng disappeared into the crowd did Fang Ziye turn and walk towards the parking lot.
The research topic has been decided.
Just waiting for the approval confirmation!
Systemic treatment is time to move to clinical practice. (End of Chapter)
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