top student at medical school

Liu Guo is, after all, his wife, and her sudden sentimental remarks actually made Nie Mingxian feel a little sorry for her.

Actually, Liu Guo is really outstanding! Being able to enter a sanatorium at this age is a recognition of her strength and talent.

Fang Ziye was just too abnormal, to the point that even a genius like Liu Guo often felt ashamed of himself, and after working on a project with him once, he didn't dare to "hang out" with him again!
Liu Guo possesses the arrogance of a genius, but Fang Ziye has the confidence and charisma of a top figure, and his abilities are also unique.

Nie Mingxian comforted Liu Guo, "Really, to borrow your words, don't think too much about it."

"Many times, Liao Jia and I have felt that Fang Ziye shouldn't even exist in this world!"

“It is only by removing his world that it appears more real; otherwise, all rules and laws would be as if they were nothing.”

"Take spinal cord injury treatment for example. Even if it's the most advanced research topic, making progress within five years would be considered a medical miracle of the 21st century."

"Damn, it's finally on the right track after just over six months!"

“I wouldn’t even believe it if the script dared to be written like that, but it’s the truth, and I was one of the people who pushed it to happen.”

Fang Ziye borrowed a joke from the internet: "Brother Nie, stop bragging, your tongue and oral muscles are about to cramp, have a sip too."

"Fang Ziye still has high emotional intelligence, let's not talk about it." Nie Mingxian took the initiative to raise his glass.

Song Yi followed, looking at this former 'classmate' and then at Fang Ziye, feeling as if he had lived through another world.

However, Fang Ziye is exactly the kind of person Song Yi wants to be. Song Yi admires Fang Ziye and wants to become Fang Ziye. He feels that he is on the right path.

Song Yi is not an easily satisfied person!
……

"I'm sorry, I'm sorry, everyone, I'm late." It was almost nine o'clock at night, and the dinner party was almost over when Li Yuanpei finally arrived by taxi. After getting out of the car, he began to apologize in a humble voice.

"Yuanpei, where have you been? Didn't you say you were leaving right away?" Fang Ziye asked.

Li Yuanpei said, "Hey, what else could it be but logistics?"

"My mentor's research group ordered a batch of cells, but it turned out that the company that placed the order was a pimp. When the cells arrived, they were found to have lost all their viability."

"After inquiring, I found out that they also placed the order at the last minute after we placed our order."

"I'm blacklisting them."

Fang Ziye frowned: "How big is the loss? What did the company say?"

Basic cell experiments definitely require cells; if there are problems with the cells, the laboratory may suffer significant losses.

"It's alright, around ten thousand or so."

"The company doesn't know whether it will compensate or not, but the contract is there anyway. If it doesn't compensate money, it will compensate for the losses. We'll just report it."

"We can't just leave this vacancy like this, otherwise we won't be able to explain it to the funding committee. If they misunderstand and think we embezzled it, that would be a real problem."

Only after saying this did Li Yuanpei add, "Brother Nie, Sister Liu, I wish you a happy marriage and many children."

Nie Mingxian also raised his glass and said politely, "Brother Li, please be sure to help me out in the future."

Fang Ziye's gaze swept back and forth between Nie Mingxian and Li Yuanpei.

Liu Guocai explained, "Professor Fang, didn't I say before that I'd leverage your connections? After Li Yuanpei heard that Nie Mingxian and I wanted to conduct a minimally invasive tumor research project independently, he connected us with a top expert in minimally invasive tumor surgery. We might be able to collaborate with their clinical team on a project involving expanded minimally invasive breast and thyroid surgeries in the future!"

"The medical significance of this surgery is actually very limited, and in reality, most of the patients with these two diseases are girls."

"Women dress up for those they want to please. They're just sick, they haven't done anything wrong, so they still have the right to pursue beauty!"

Fang Ziye said, "No, Sister Liu, I think this topic is very good."

"The significance of medical development lies in three points: one is to make medicine more beautiful, one is to make it simpler, and one is to make it more effective."

Li Yuanpei said, "Ziye, I told Professor Zeng of the Department of Breast and Thyroid Surgery at West China Hospital that you were also involved in this project."

"You wouldn't believe it, after I mentioned your name, Professor Zeng was grinning from ear to ear. He even wanted to discuss the development of new chemotherapy drugs for breast cancer with you!"

"be careful."

"There are plenty of women here, what do you mean by 'can't close your legs'?" Fang Ziye cursed.

"He didn't close his legs properly. He stood up right then and there and kept laughing until the call ended. If I hadn't told him you were busy lately, he probably would have flown over already."

"Professor Zhang Yue of West China Hospital is really outstanding. He has made you famous in the field of surgery at West China Hospital."

"However, Professor Zhang is also a restless person. After leading the team to develop the steel plate of the CC new material, he continued to lead the team to develop other devices using the CC new material, such as heart valves and artificial blood vessels..."

"It really is very interesting."

"I reckon you'll be in for a lot of trouble then," Li Yuanpei said.

Fang Ziye's eyes brightened, and he said, "This is a good thing, how could it be trouble?"

"By the way, Yuanpei, have you compiled a list of the PhDs assigned to me from this campus? Don't just give me their names. Make sure you know exactly how many there are, what each of them specializes in, and what their major is."

"Are you sure you can manage to bring them all?" Li Yuanpei nodded first, then asked.

"I'm doing this to select people. If I find another Hu Qingyuan, I'll have hit the jackpot. As for the others, I'll make sure they graduate on time."

"If someone is even more talented, the chances of them staying in the hospital are not small."

"We're still short-staffed for that new miRNA project. Besides, there are also projects on spinal cord nerve location determination and exocrine function. I could handle two hundred people!" Fang Ziye said.

"What exocrine function?" Nie Mingxian asked curiously.

Fang Ziye is planning something big.

"It's a classic surgery in our orthopedics department, also known as bone lengthening surgery or Ilizarov surgery. After cutting the cortical bone (preserving the medullary cavity and periosteal blood supply), we use an external fixator or intramedullary nail to apply daily traction (about 1 mm/day) to stimulate local tissue to produce distraction osteogenesis, and the new callus gradually calcifies and lengthens."

Li Yuanpei asked, "Is that roughly the meaning?"

Since Hu Qingyuan wasn't there, no one could remember the straight man, so Fang Ziye had to explain it himself: "It's probably what Li Yuanpei meant, but currently this surgery is only used in clinical practice."

"And it not only causes bone to grow, but also nerves, blood vessels and other structures to grow again."

"Currently, this surgery is only used to observe the phenomenon, and the more specific growth mechanism has not been explained."

"But based on my personal understanding and speculation, our muscles and bones may secrete something when they are under stretching, such as hormones or something else that has not yet been discovered."

"This substance can stimulate the local regeneration activity of already mature cells."

"It's just a matter of physical factors; it shouldn't be that serious!"

"Otherwise, it would be impossible that no other organs have been found to exhibit stretch growth in animal experiments over the years... Based on this phenomenon, there must be some biological substance that promotes this growth phenomenon."

After Fang Ziye finished explaining, both Nie Mingxian and Liao Jia were so shocked that their scalps tingled.

So incredulous was Liao Jia that she poured beer into her hands and rubbed her temples to calm herself down.
Nie Mingxian, standing to the side, blurted out, "Fang Ziye, are you trying to completely overturn and reshape modern medicine from top to bottom?"

The Ilizarov theory is a well-established orthopedic theory, a phenomenon, and a surgical procedure. It has long been used in orthopedics and is a common surgical method for many trauma patients.
It's fair to say that it's been around for over seventy years, and most people only think about how to use this surgery, without really tracing its underlying principles.

Its significance at present is...

Biological mechanism: Applying slow, continuous tension to living tissue can stimulate cell division and proliferation, and activate the tissue's regenerative potential.

The philosophical significance lies in the dialectical unity of mechanical force and the self-healing power of life, breaking the fixed mindset that "tissue regeneration requires growth factors/stem cells" and proving that physical stimulation itself is a powerful biological signal!

These are the two recognized advantages of this surgery within the current medical system.

However, Fang Ziye said that this may not be the case. Physical stimulation is only the cause, not a strong direct biological signal, but rather a prelude to the cause of the biological signal.

One can imagine what would happen if Fang Ziye actually discovered this exocrine body and extracted it.

Who knows if this thing can regenerate a penis, allow heart cells to multiply again, or regenerate a cornea...

If all of the above can be verified, many specialties in modern medicine will be overturned.

Not just trauma surgery, not just orthopedics, not just general surgery!!!

Fang Ziye's voice and tone were calm.

His announcement proved that the matter could proceed. Fang Ziye's tone was calm: "Modern medicine, judging from its name, is not associated with classics or authority."

"Many people say that modern medicine is Western medicine, but that's not true. Modern medicine is a dynamic development system based on molecular biology, guided by evidence-based decision-making, driven by interdisciplinary technologies, and aimed at reducing the burden of disease!"

"Is the dynamic clear now?"

"Modern medicine, at least in our Chinese textbooks, has recognized the efficacy of many traditional Chinese medicines and herbs, so it has included them in textbooks."

"If that's the case, then what's the point of disrupting things? It's just development!" Fang Ziye said, glancing at Luo Tingzhu beside him with gentle eyes.

Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is a progressive and fatal neurodegenerative disease that selectively damages motor neurons.

Its characteristic feature is the simultaneous degeneration of upper and lower motor neurons, leading to progressive muscle atrophy and weakness, and ultimately death from respiratory failure.

The essence of this disease is the collapse of motor neuron protein homeostasis triggered by multiple factors. Through literature review, Fang Ziye found that the molecular mechanism is gradually becoming clearer (TDP-43 pathology is the breakthrough point), but treatment is still limited to delaying rather than blocking the disease.

In the next decade, gene editing combined with neuroprotective glial cell regulation may become the key to breaking the deadlock!

However, Fang Ziye, the gene-editing technology expert, had discussed the matter with gene-editing experts he had previously 'collaborated' with, and it was truly like finding a needle in a haystack.

Therefore, Fang Ziye could only find a breakthrough in the vast amount of medical knowledge by focusing on key points.

The key points of the disease.

A progressive, fatal neurodegenerative disease that selectively attacks motor neurons.

Keywords: motor neuron - spinal cord injury.

Keywords: necrosis, Ilizarov technique, traction regeneration!

Fang Ziye's goal was clear and simple from the beginning: to save Luo Tingzhu's father.

However, things cannot be accomplished overnight. In fact, Fang Ziye did not dare to directly target ALS, because he had already carefully considered the consequences of going straight into a fight.

Therefore, the only option is to take the "encirclement" approach!
Breaking the deadlock in basic scientific research!!
Liao Jia finally finished off half a bottle of beer, swallowed hard, and said in a low voice, "Fang Ziye, Professor Fang, godfather."

"No...brother."

"Can I keep this?"

Liao Jia is not a peaceful person; what he wants to do most is cause trouble.

He wants to do things that others can't, and the more novel the thing, the more it stimulates his desire.

Liao Jia was genuinely afraid that Fang Ziye wouldn't want to take him on. In truth, his desire had already reached the Yangtze River through his eyes, like the ripples on its surface. Just thinking about it made him feel like he could never do it again...

If Fang Ziye says he won't take him, Liao Jia will feel upset and might even develop Yu Yu syndrome.

As the saying goes, people with some ability will have awareness, as well as "ambition," desire, and the ultimate goal of "self-actualization."

Compared to Fang Ziye's current approach, what are those previous topics worth?
How about we all step aside?
However, the original concept for this topic actually originated from a traditional technique from decades ago!
Nie Mingxian's Adam's apple bobbed up and down, Liu Guo's gaze began to freeze, and his breathing gradually became rapid.

She realized that she had spoken too soon and shouldn't have said she wasn't qualified.

It's fine to be a slacker.

Song Yi was already not very "present," and now that he had told the whole truth, his diaphragm was twitching so badly that he was almost having trouble breathing.

If he hadn't been suffocating, he would have forgotten that he was a breathing 'animal'!
"Hoo~~" He took a deep breath and quickly tried to save his life.

Luo Tingzhu's belly didn't show, because she had expected it all along, and she was the calmest.

Even though she was calm, even though she knew beforehand, her eyes still gleamed when she saw the reactions of these "acquaintances".

Senior brother is so handsome, senior brother is so outstanding, senior brother always shocks people, senior brother always makes the world chaotic.

But actually, it's not that I, Luo Tingzhu, am not good enough; it's just that my senior brother is too amazing.

Before him, all beings are equal.

Am I not good enough for him? That shouldn't be the case...

Compared to Sister Liu Guo, I have a slight edge in clinical skills and a slight edge in research skills.

Compared to fairy tales...

Compare……

Luo Tingzhu's mind became distracted.

Fang Ziye gently grabbed Luo Tingzhu's hand and said, "What are you doing? Are you trying to eat someone?"

“I am taken.”

"Sexual orientation!~"

Nie Mingxian glanced at Liu Guo, then burst out, "Liu Guo, Fang Ziye must have already planned this out! But he's just so shameless, he had to wait until we made fools of ourselves before begging him."

"I really want to hit him!"

"Brother Liao, are you coming or not?"

Liao Jia shook his head.

Nie Mingxian looked at Song Yi, and Song Yi shook his head as well.

Li Yuanpei's gaze was unfriendly.

Liao Jia couldn't find any help, so he immediately changed tactics: "Bro... little brother, say something! I was just joking."

"I'm very excellent." Liao Jia, an associate professor, was unusually obsequious at this moment.

"As I said, of course everyone who listens will benefit."

"Don't look at me like that. I've had this idea for a long time, but am I also thinking about becoming the President of the United States? Do you think I'd bring this up every day?"

"We definitely need to have a solid foundation of preliminary research before we can put it on the agenda."

“Otherwise, what’s the difference between me and other people who just make empty promises?” Fang Ziye’s voice was very calm.

The Yangtze River flows on and on, unchanged for millennia.

There was no rain today, the wind was light, the waves were not high, and there was nothing special about it.

The terrain here is calm, without raging waves, towering mountains, flashing lights, or thunderous roars!
But on such an ordinary night, in such an ordinary location, at an ordinary barbecue stall, during an ordinary gathering, Fang Ziye set out a research topic.

The others remained silent, as if they wanted to play supporting roles and let Fang Ziye perform his solo act well!
However, Fang Ziye was already used to it.

He picked up a beer bottle and tapped it on the table: "Come on, don't just stand there, let's drink!"

"You're not going to eat or drink anymore?"

"Boss, another serving of steamed egg." Fang Ziye broke the silence of the eight or nine people having dinner together.

Li Yuanpei had long intended to leave the fields of scientific research and clinical practice, so even though he knew that what Fang Ziye was talking about today was very important and could even affect multiple scientific disciplines in medicine, overturning tradition and classics for decades or even centuries to come!

She slowly pulled herself together, but her voice remained soft, afraid of angering others and becoming a target of attack: "Brothers, I just arrived, my stomach is empty, and I'm thirsty."

"How about we eat and drink something?"

"I'm scared by what you're doing."

Li Yuanpei definitely didn't eat anything!
The atmosphere at the scene could indeed make a newcomer afraid to eat.

Li Yuanpei defused the current atmosphere by getting himself involved.

Although Fang Ziye did not reply to Liao Jia and Nie Mingxian, he had actually given his answer.

The thoughts of several people have returned to the right path.

team!

team.

A team has a core member, and then there are members. Fang Ziye never thought about changing people. Fang Ziye is very dedicated. They were just overthinking it.

This kind of thing should happen naturally, not as a "reward" from Fang Ziye!
Liao Jia opened a new bottle of wine, carefully poured it into the glass in front of him, half-raised it, and said softly, "Brother, drink! ~ A toast to you."

He is not my godfather, not Professor Fang, and not Ziye.

"Let's drink together... Don't let others laugh at us, it'll make us look like we're acting like teenagers..." Fang Ziye continued to break the ice.

"So what if I'm a chuunibyou? Let whoever wants to talk about it say so!" Liao Jia said nonchalantly.

I'd die for my brother!

...(End of chapter)