Era: I have a two-world door

Chapter 612, Good News for Men
Wang Qingsong looked at the other party, thought for a moment and asked, "Shirley, you are a surgeon in the hospital! Don't you know how to do drug research?"

Hearing this, Shirley burst out laughing.

"Yes, there are many categories of medicine. I studied clinical medicine, and the drug research you mentioned is pharmacology. Although we also have research topics, the direction is different from pharmacology."

Then he asked, "Mr. Wang, are you also interested in drug research?"

After Wang Qingsong listened, he was thinking about it.

Nodding gently: "Well, I am somewhat interested. I want to set up a team to help me develop drugs."

"Developing drugs?"

Shirley didn't say anything, but Du Wanting next to her felt her scalp tingling.

What is this guy trying to do again!

Wang Qingsong smiled and nodded.

In fact, when he first heard about drug research, he thought of a lot of things.

One of them is to get some popular Western medicines from the future and develop and produce them directly here.

Money has to be made.

Another reason is traditional Chinese medicine.

In later generations, the Japanese applied for patents for many traditional Chinese medicine prescriptions, leaving the mainland with only prescriptions but many medicines unable to be produced.

Or it can be produced but not exported.

Once exported, if there is patent infringement, it cannot be sold.

If he sets up a pharmaceutical company, he can apply for these patents.

Moreover, in a few years, many ancient Chinese medical books will be destroyed, so it would be a good choice for him to preserve these recipes.

Retracting his thoughts, he smiled and said, "Yeah! I have this idea."

Shirley shook her head and asked, "Do you know how much money is needed to invest in a drug from research and development to production and marketing?"

"I don't know the exact amount, but it will probably cost more than 10 million US dollars."

"Yes! This is still to improve the laboratory, because the research and development of many drugs are by-products of other experiments. If it is a new laboratory, the cost will more than double. Investment is a problem, and time is also a big problem. For a drug to go from research and development to market, it takes at least several years, and it can take as long as ten or even twenty years."

Wang Qingsong nodded lightly when he heard this.

Of course he knows.

Wasn’t Viagra originally used to study heart diseases? In the end, it was discovered that it was not very effective and instead had a special effect on a certain part of the body.

In fact, during this period, many companies rely on a hit product to develop into industry giants in the future.

Technology is, and so is the pharmaceutical industry.

Seeing this, Shirley continued, “Drug development requires several stages.

In the early stage of research, the scientific research team screened thousands of compounds and evaluated the activity and safety of the molecules through in vitro experiments and other means, which took an average of 3 to 6 years. The failure rate at this stage exceeded 95%, and only a few compounds entered the next stage.

The preclinical research phase verifies the effectiveness and safety through cell experiments and animal toxicology experiments, and simultaneously conducts formulation process development and stability testing, which takes 1 to 2 years. During this phase, the drug production quality management specifications must be completed to establish a standardized production process.

Clinical trial application, submit clinical research application, including pharmacy, pharmacology and toxicology, clinical plan and other information.

The clinical trial phases are divided into Phase I to III: some drugs require Phase IV clinical trials and continuous monitoring of adverse reactions after marketing.

This will probably take another 3 to 6 years.

......"

Shirley was there talking about the complexity of pharmaceutical manufacturing.

Wang Qingsong nodded slightly. He also knew that drug research and development required a lot of time.

After thinking for a while, he said, "What if I have a formula for a drug that has not yet been patented? How long will it take for it to be on the market?"

Shirley frowned and asked, "What medicine are you talking about? Western medicine or Chinese medicine!"

"Western medicine!"

"If a compound or biologically synthesized Western medicine is about to enter the clinical trial stage, it depends on the progress. If it is fast, it will take about two years, which is already a relatively fast result. If it is slow, it will take about seven or eight years."

Shirley finished and asked, "What medicine are you talking about!"

Wang Qingsong came back to his senses, thought for a moment and said, "Well... I'm going to go get something, you guys talk first."

After saying that, he stood up and left.

The two of them were left there chatting.

Shirley looked at his leaving back and said softly, "Crzy~ That girl just now looked at your man with a strange look in her eyes. There must be something wrong between them."

Hearing this, Du Wanting followed her gaze and looked at Axia who was working in the distance.

He retracted his gaze and smiled, "I know! There are some things I can't stop."

Shirley shrugged when she heard that.

"The Qing dynasty has been gone for so many years, how can these men still have three wives and four concubines? I really don't understand. Unfortunately, if a woman wants to have many men, she can only use money, not official means."

Du Wanting agreed with the first sentence very much, but was speechless after hearing the second sentence.

He rolled his eyes and said, "What are you talking about! If you want, you can find eight or ten. You are not without money. You have a lot of dividends this time!"

Shirley smiled when she heard this: "It has to be you! If you hadn't asked me to be in charge of hyaluronic acid, I would still be an ordinary doctor in the hospital!"

Du Wanting naturally knew that she didn't understand medical matters, and Hess was not her relationship.

Plus, she also needs someone to be in charge of the cosmetics industry.

Because of this, Shirley spent much less time in the hospital. Otherwise, her chances of winning this competition would be very high.

Then he asked, "What do you think? Come out of the hospital! The company also needs a stable leader."

Shirley put away her smile and said, "Please let me think about it again!"

Du Wanting nodded when she heard that, and the two chatted there for a while.

After a while, Wang Qingsong came back with some things.

"Ms. Shirley, take a look at these two drugs. They are not on the market yet. They are not patented either."

Shirley took it and looked at it.

"Atorvastatin, indications: 1. Hypercholesterolemia 2. Patients with coronary heart disease or coronary heart disease and other critical diseases (such as diabetes, symptomatic atherosclerotic disease, etc.) combined with hypercholesterolemia or mixed dyslipidemia,
This product is indicated for: reducing the risk of non-fatal myocardial infarction, reducing the risk of fatal and non-fatal stroke, reducing the risk of revascularization, reducing the risk of hospitalization due to congestive heart failure, and reducing the risk of angina pectoris. ..."

Shirley looked surprised as she watched.

The content here is so detailed.

Except for clinical trials, everything else is basically available.

Even pharmacology, toxicology and pharmacokinetics are included.

It looks exactly like a finished product, but someone deliberately erased the clinical trial data.

Because many of the other information Wang Qingsong provided contained results and data that could only be obtained through clinical trials.

Then he looked at the other one.

"Sildenafil?"

After saying that, he looked at Wang Qingsong with a strange expression.

Asked: "Is this a drug for treating male erectile dysfunction?"

Wang Qingsong nodded.

He still felt a little embarrassed to talk about this medicine so openly.

He specially selected these two products.

Atorvastatin, the first drug to exceed $100 billion in annual sales, promoted the popularization of the concept of secondary prevention of cardiovascular disease. Of course, this was a product launched in the s.

As for sildenafil, there is no need for much introduction. Adults know about it even if they have never used it.

Shirley looked at him seriously, but her face still looked a little unnatural. She teased him, "Oh, you're still shy! Crzy, could it be..."

Du Wanting also heard it and rolled her eyes at him in annoyance.

"Be serious, let's talk business!"

Hearing this, Shirley put away her expression and spoke in a serious tone.

"Mr. Wang, are you sure these two drugs are not available on the market now?"

Wang Qingsong also smiled when he heard this: "Yes or no, Miss Shirley is a doctor, she should be very concerned about this matter!"

"That's not necessarily true. I'm not a god. Some drugs are not sold in Hong Kong Island, so I'm not sure. But Queen Mary Hospital is connected with King's College London Medical School, and they regularly update technology and drugs. At least the UK doesn't have that."

Shirley thought for a moment and said.

Wang Qingsong hummed: "Yes, I'm sure there isn't one now."

Shirley pondered for a moment before saying, "If this is true, then this medicine is extremely important."

Seeing the two people's thoughtful expressions, she continued, "Because there is still no drug that can lower hypercholesterolemia, I only know that there are companies that have been developing related products. If this drug is launched on the market, the profits will be immeasurable.

Not only atorvastatin, but sildenafil is also the first drug to treat male dysfunction. ”

Wang Qingsong pondered there after hearing the words.

This drug for lowering hypercholesterolemia has defeated many similar drugs and ascended the throne of the king of medicine.

It went public in 97 and set its first record of billion yuan in sales that year.

And in the next ten years, the annual revenue was over 10 billion US dollars.

It's the 1960s now, even if the purchase volume is not that large, it should be at least 1 billion!

He collected his thoughts and said with a smile, "Ms. Shirley, if I want to develop these two drugs, can I start directly from the clinical trial stage? I can provide other information. How long will it take for them to be on the market?"

Shirley heard this and looked at the information above.

Finally, he said, "Yes, I estimate that it will be available in two years, or at most three years, but before that, we need to apply for a patent. And we need to apply for it simultaneously in the United States and the United Kingdom."

Wang Qingsong said, "Take these materials first. I don't know the process. I will get the subsequent synthesis method as soon as possible."

Naturally, he would not reveal the synthesis method, but at least he had to register it first.

Shirley was excited when she heard this: "By the way, the research and development of this drug is in the name of the company. Can I be listed as a member of the company, even if it's just an assistant?"

Wang Qingsong smiled when he heard this: "Sure! No problem. I only look at the results. Maybe you can find someone to be your assistant and you can take charge. You can discuss the company's affairs with Wanting."

He knew that drug research required pharmacologists and he definitely needed to recruit a group of such talents.

It certainly won’t work just relying on Shirley.

Shirley was delighted when she heard this: "Great! If this is reported, then my position will be secure. Even if the other party has a father on the board of directors, he won't have a chance. After all, this is a drug that is not available on the market. It is also a huge honor for the hospital."

Wang Qingsong also expressed his approval.

Conducting experiments requires cooperation with hospitals, which is unavoidable.

"That's a good thing then."

Shirley was helpless when she saw this: "But if this happens, I will have less time to attend university classes and have surgery in the hospital."

Du Wanting smiled when she heard this: "Then save some time and come out. It seems that you can't quit your job in the hospital right now."

Queen Mary Hospital is a collection of teaching and research bases, providing a research base for the HKU Faculty of Medicine's education and research projects in medicine, nursing, pharmacy and other biomedical sciences.

She is still in the hospital so many things will be convenient.

Hearing this, Shirley felt conflicted.

She loved the feeling of being on the operating table.

But for the sake of money, she might have to give up some things.

"Okay! I'll try my best."

Wang Qingsong smiled when he saw this.

Perhaps a multinational pharmaceutical company will appear in Hong Kong in the future.

After calculating the time, he found that if the drug could be launched in three years, it would bring him a large amount of funds to be used for the Hong Kong real estate crisis in a few years.

After the matter was settled, Du Wanting thought of something and said, "Ah Xuan, let me tell you something. The telephone company in the United States contacted us and wanted to buy our patented technology. I didn't agree, and now they want to cooperate with us."

Wang Qingsong shook his head when he heard this.

"We can't cooperate for now!"

"Why? This is also a good opportunity."

Du Wanting was confused for a moment.

Wang Qingsong was also helpless when he heard this: "There is no way, we don't have the technical staff, so we can't cooperate!"

If this thing was developed in this era, then there is naturally no problem.

It can definitely be supported technically.

But his stuff was moved here, and it was second-generation technology, so there was no way to cooperate!
The technical accumulation of this thing requires a lot of scientific and technological talents.

What he needs to do now is to master this technology thoroughly.

Even if it is just copying, you can still cooperate with the person on the other side.

This is also the reason why he spent so much effort to move the circuit boards and chip technology over.

He hopes that one day, as long as he takes over the technology, there will be a large number of talented people to help him commercialize it.

This is the final result.

Hearing this, Du Wanting was also tangled: "Okay then!"

Wang Qingsong thought of something and asked, "By the way, how is the admission of HKU graduates by Huazhong University of Science and Technology? How is the progress of students majoring in electrical and electronic engineering?"

The major of electrical and electronic engineering is actually the major of communications engineering.

In the next few years, it has been ranked very high in the world.

He needs such talents.

He recruited these people to lay the foundation for the technology company.

Du Wanting heard this and said softly, "I looked at the data a few days ago. A total of 56 people were enrolled, including 2 doctoral students, 17 graduate students, and the rest were undergraduates. There are only 7 students majoring in electrical and electronic engineering, including doctoral students."

Wang Qingsong still frowned when he heard this number.

The quantity is still not enough!

Especially in the communications major, there are only 7.

But think about it, there are only more than 2,000 students in HKU now, and the academic system of HKU at that time is three years.

The average number of graduates is only seven or eight hundred.

There are even fewer people majoring in communications.

He was already surprised to have two doctors here.

"Okay then, let Spock continue recruiting people later."

Rome wasn't built in a day, so there's no point in being anxious.

(End of this chapter)