Come on, Dr. Wu

Chapter 475 Crystallized Organization
With full of doubts, the thin and sharp puncture needle slowly extended into the patient's liver.

In fact, Wu Xiaofu had already made full preparations before the puncture. He knew very well that if the puncture could find a tumor, it could be taken for pathological analysis.

However, what appeared in front of Wu Xiaofu at this moment was not a tumor, but even so, he did not feel that the series of measures he had just taken were wasted.

After all, no matter what treatment plan is adopted for the patient next, a piece of tissue must first be removed for pathological examination to find out exactly what condition caused the patient's current condition.

Wu Xiaofu said seriously, "Get the pathology."

After hearing this, Peng Xia, who was distracted at first, came to his senses immediately and quickly began to prepare the pathology bag.

Although abdominal puncture is rarely used to obtain pathological samples under normal circumstances, since Wu Xiaofu has completed the previous operation steps so skillfully, let alone just taking a pathology sample, even if he really used abdominal puncture to directly perform a small operation, I am afraid Peng Xia would not be too surprised.

Because for experienced doctors, obtaining pathological tissue through puncture is a common and routine medical method.

For example, if you want to obtain kidney pathology information, you can choose kidney puncture; if you need to know the specific situation of the bone marrow, you will do bone marrow puncture, etc. However, at this moment, Peng Xia really didn't know from which part Wu Xiaofu was going to obtain the required pathological tissue.

Wu Xiaofu completely ignored the puzzled look on Peng Xia's face. He was now concentrating on the operation. He carefully removed a small portion of tissue from the liver, while deliberately avoiding the common bile duct.

You know, the common bile duct is so severely crystallized that if you accidentally touch it, or even take a small pathological sample, it is very likely to rupture and leak. Once this happens, the consequences are simply unimaginable.

In contrast, the liver is in much better condition. Although there is also crystallization, it is distributed in a dotted manner, and the liver itself has a strong regenerative ability.

Therefore, even if a small piece of tissue is removed, it will not have much impact on the structure and stability of the entire liver.

The next step was to take the pathological sample. Wu Xiaofu skillfully picked up the puncture needle, quickly and accurately inserted it into the designated position of the liver, and then with a gentle pull, he successfully took out the required sample.

At this moment, the patient who was lying quietly on the operating table suddenly let out a "hiss". However, it was only half a cry, because Wu Xiaofu's movements were too fast and neat. Before the half cry was fully uttered, the whole process of taking the pathology was already over.

However, don’t think that this is the end of the story. How to bring out the obtained pathological samples safely and intact is the key to truly testing the technical and operational level.

If you are not careful, not only may the sample be damaged, but other complications may also occur, which is why pathological tissue is rarely obtained by abdominal puncture. Fortunately, these are not insurmountable obstacles for the experienced Wu Xiaofu.

Wu Xiaofu was seen carefully using a thin cannula to gently pull out the pathological tissue block removed from the liver.

That small piece of tissue was like a precious treasure and was treated carefully by Wu Xiaofu. He had to pay attention to whether the pathological tissue would change after encountering the external environment. Now it seems that it is not so bad.

The removed pathological tissue is gently placed in a transparent pathological bag.

The patient's family members gathered around, staring at the bag of pathological tissue with wide eyes, but it was obvious that they could not figure out what was going on.

Even Peng Xia, who was relatively experienced, could not help but feel puzzled when he saw the slightly strange pathological tissue in the pathology bag. This tissue seemed to be different from normal liver tissue, and its color was a little whitish, as if it had been soaked in ascites for a long time.

"Okay, please be patient. We still need to observe and analyze the pathological tissue further to understand the patient's condition. Please don't worry, the results will be out soon."

Wu Xiaofu told the patient's family and left the ward with the pathology bag. However, Wu Xiaofu did not follow the usual procedure and let Peng Xia simply send the pathology sample to the pathology department. Instead, he personally picked up the bag of pathology tissue and walked straight to the pathology department.

As soon as he entered the pathology department, Wu Xiaofu greeted the director Wu Guozhu, and then, without any delay, he asked Wu Guozhu for the relevant testing equipment.

After getting the instrument, he quickly found a place to sit down and skillfully fiddled with the glass slides, preparing to start pathological analysis.

Wu Guozhu, who was standing by, was surprised to see Wu Xiaofu busy. This hero who had just returned from abroad and was said to have been granted leave, was actually doing pathological analysis himself instead of taking a good vacation. What was going on?
"Hey, Director Wu, you are very experienced. Can you come and take a look at what is going on?"

Before Wu Guozhu had time to have too many doubts, Wu Xiaofu quickly stood up with a look of surprise that was hard to conceal on his face.

Seeing this, Wu Guozhu walked straight to the microscope without saying much and sat down slowly. When he observed the scene inside through the eyepiece, he couldn't help but blurt out: "This is...?" His voice was also full of surprise.

You know, Wu Guozhu has a lot of medical experience. He has been engaged in medical work for thirty years, and he has served as the director of the pathology department for ten years. In the past years, he has observed countless pathological specimens.

However, even an experienced doctor like him could not help but feel a sense of novelty when facing the pathological tissue in front of him. Because this situation is so rare that it can be described as rare. Of course, it is just rare, not unheard of.

"Teacher Wu, which patient did you get this from? I haven't seen such a special pathological tissue in person for many years!

Thinking back carefully, the last time I saw a similar situation seemed to be more than a decade ago. I remember that at that time, a patient suspected of lung cancer took a bronchoscope to obtain pathological tissue, and unexpectedly, such a strange sample was taken out.

I was really surprised at that time, because I had only read about this rare pathological form in books before, and I had almost no experience of actually handling it myself!
It neither belongs to the category of common tumor lesions nor is it the result of inflammatory response in the ordinary sense.

It can be called fibrosis, but it clearly has more erosive characteristics than general fibrosis.

Faced with such a mysterious and complex situation, we spent a lot of time looking up a lot of medical information and research literature. After in-depth research and analysis and discussion, we were finally able to accurately determine that it was a crystallized tissue type. "

I have to say that calling it "crystallized tissue" is quite appropriate! Usually, if you encounter only general fibrotic tissue, the problem may be relatively simple.

At most, the corresponding organs will lose their normal physiological functions. But as long as the root cause of fibrosis can be successfully eradicated and the subsequent fibrosis process is ensured not to continue to spread, there will basically be no major troubles or serious consequences. However, the crystallized tissue in front of us is very different...

The crystallized tissue has characteristics very similar to tumor tissue and has strong erosive ability. It is like a ferocious beast, ruthlessly devouring the surrounding normal tissue.

Once an organ that was originally functioning normally is invaded by this kind of crystals, it will not only lose its original physiological function, but the condition will also deteriorate rapidly like a wild horse running out of control.

Worse still, crystallization makes the patient's internal organs fragile, like fragile porcelain. If one is not careful, the organs will be damaged, leading to a series of serious consequences.

For example, bleeding occurs frequently and inflammation spreads rapidly like a prairie fire.

As time goes by, these problems continue to accumulate and even the strongest patients may find it difficult to withstand such a heavy blow.

As for the cause of ascites, the answer becomes clear when you see the crystallized liver and gallbladder with your own eyes.

It should be made clear that this crystallized liver condition is much more difficult and dangerous than common cirrhosis. It is like a time bomb hidden in the human body, which may explode at any time and bring disaster to the patient.

"So what was the patient's condition at that time?"

Wu Guozhu gently shook his head in response to Wu Xiaofu's question, showing a look of helplessness and regret on his face, and slowly said: "This disease is so rare that it is no exaggeration to say that it is extremely rare worldwide.

Until now, there has not been a single successful case of cure, let alone a complete cure. Even the cause and epidemiology of the disease are still not fully understood!

Because it is an extremely rare case, I also inquired about the relevant information from many sources and paid special attention to it. The patient was initially suspected of having some genetic problems, so he underwent genetic testing.

However, after a thorough examination, it was found that there was no genetic mutation or anything like that. Then we considered whether it could be caused by the work environment, just like silicosis.

But after a closer look, we found out that the patient's daily job was just to sit in the office and drink tea and read newspapers leisurely. It was impossible for him to be exposed to factors that could cause the disease! So, until now, no one can explain what is going on.

Moreover, the drug treatment for this disease was not very effective. It seemed that within two years, the poor patient passed away.

At first, I thought the disease only affected the lungs, but now I have discovered similar symptoms in the liver as well.”

Although those pathological tissues are in a crystallized state and exist in the form of tissue fragments, they are still mixed with some normal tissue components.

After all, when obtaining pathological samples, it is almost impossible to accurately and precisely cut out the pure lesion area.

Especially the crystallization phenomenon in the liver, which is distributed in a dot-like manner. The small dots are closely arranged like stars, which makes people dazzled and difficult to distinguish clearly.

As an experienced and established pathologist, Wu Guozhu is very familiar with the tissue morphology of organs such as the liver and lungs. He can make an accurate judgment quickly with just one glance.

"Not only is there a problem with the liver, but also with the common bile duct. The condition is even more serious. The entire common bile duct has completely crystallized."

Wu Guozhu couldn't help but marvel at this, but he didn't ask how Wu Xiaofu knew all this. In his opinion, maybe Wu Xiaofu discovered it by chance during the operation. At this moment, facing such a difficult case, Wu Guozhu couldn't help but marvel at it.

After a short pause, Wu Guozhu rubbed his hands and asked with concern: "In this case, what are you going to do next?"

Since Wu Xiaofu did not follow the regular pathology procedure this time, the relevant information has not even been recorded in the computer system. Therefore, strictly speaking, this can only be regarded as a pathology examination and discussion conducted privately.

To be honest, Wu Guozhu was not very willing to take over such a troublesome matter. The reason was very simple - even he himself did not know how to give a reasonable and appropriate pathology report.

You know, this is the top pathology laboratory in the country! If we only give a simple report on crystallization, once it gets out, we will probably become a laughing stock in the industry.

Therefore, when Wu Guozhu said that, his real intention was to hope that Wu Xiaofu could quickly take the report away and he would handle the related matters personally.

Wu Xiaofu pretended not to understand Wu Guozhu's hidden meaning and continued, "Take a closer look? I don't know why, but I still feel there is something wrong here.

I have reviewed the patient's medical records, various examinations and test results, and even epidemiological data.

However, even if crystallization occurs, there must be a reasonable reason. Now that these key evidences are clearly in front of us, it would be a shame if we can't figure this out. "

Hearing this, Wu Guozhu glanced at Wu Xiaofu with a hint of resentment.

Wu Guozhu had no idea whether other people would laugh at him, but at this moment, he clearly felt that Wu Xiaofu was secretly making fun of him. After all, these words were tantamount to implying that he, the director of the pathology laboratory, had no idea what to do when faced with the pathological tissue in front of him.

After thinking about it, he decided not to argue with Wu Xiaofu, because he also felt that the pathological tissue was right in front of him, and if he really couldn't see it, he would laugh at himself and feel that he had learned it in vain.

"Just wait, this is not ten years ago anymore. We have the equipment."

(End of this chapter)