They’re all reborn, what’s wrong with being a little more almighty?
Chapter 153 The shocking giant melon
Chapter 153 The shocking giant melon
Looking at the experimental report on pseudouracil modification in his hand, Zhang Wei fell into deep thought.
There is no doubt that pseudouracil modification of nucleosides can allow mRNA to deceive cellular immune responses.
The future mRNA vaccine has actually been created and has even been used by billions of people.
If this scientific research result is false, there will be no subsequent mRNA vaccine.
You can repeat the same experiment and perform pseudouracil modification on nucleosides. Why did your experiment fail?
Since it is certain that this scientific research result is true, the problem must lie with you.
There are many variables in biological experiments, such as temperature, humidity, drug dosage, etc., which will all be different, and will also cause different experimental results.
"Mammals are warm-blooded animals. A healthy mouse has a body temperature similar to that of a human body. Between 36.5 degrees and 37.5 degrees, there should be no problems with temperature and humidity.
In the experiment of pseudouracil modification, I used the pharmaceutical glycine-arginine protein and a catalyst to stimulate the production of pseudouracil synthase, which is no problem.
So the key point should be the dosage of the medicine. I either used too much medicine or too little. So should we increase the dosage of medicine, or should we reduce the dosage of medicine?
The function of the agent is to generate pseudouracil synthase. The amount of pseudouracil synthase generated is directly related to how much uracil is modified into pseudouracil.
But if half of the hundred wolves are huskies, you can tell at a glance that there are huskies mixed in with the wolves.
There are not many things that can make Ye Haotian, a sunny and cheerful boy, worry, so Zhang Wei asked curiously: "Brother Haotian, I rarely see you worried. What's wrong?"
When he returned to the dormitory, he only saw Ye Haotian sitting at his desk with a sad face.
"Isn't it winter? Animals all have a saying of putting on autumn fat, and so do people. In winter, they will gain weight. Accumulating fat is good for anti-freezing!" Zhang Wei said.
If there is too much pseudouracil synthase, there will be too much pseudouracil, causing the cells to discover that there is something wrong with the mRNA, thus stimulating immunity. This makes perfect sense in theory.
Zhang Wei immediately formulated a new experimental plan.
With new experimental ideas, the three graduate students began to get busy again.
On the contrary, the lower the proportion of pseudouracil introduced into the mRNA, which means the higher the proportion of normal uracil, it will not cause an immune response. As long as the proportion of pseudouracil is reduced to a certain critical value, the immune system can be evaded.
Zhang Wei's idea is correct. The higher the proportion of pseudouracil introduced into mRNA, the easier it is to trigger an immune response. When it reaches a certain critical value, the immune system will definitely be activated.
If we extrapolate from this basis, if there is less pseudouracil synthase, there will be less pseudouracil. In this way, cells will not be able to detect problems with this mRNA and will not stimulate immunity! "
Zhang Wei stood behind, looking at the three people who were concentrating on each other. They were standing in front of the test bench, their fingers moving lightly and nimblely, constantly picking up and putting down various utensils, as if they were performers playing a symphony.
"Is Chen Ming fat?" Zhang Wei thought for a while, and it seemed that was really the case.
"You are busy doing projects, I know that, but Chen Ming may not be busy doing experiments! You see, he has gained weight recently. If he is busy doing experiments, how can he gain weight!"
……
"I've been busy working on new projects these days. I spent most of my time in the laboratory of the Department of Biology. I really didn't pay attention to Chen Ming! The main reason is that Chen Ming has been missing out recently. It should be Professor Fang's help. Let’s do more experimental tasks!” Zhang Wei said.
It's like there is one husky among a hundred wolves. It is difficult to find this husky even if you look carefully.
After smoothing out this logic, Zhang Wei immediately realized that he had used too much medicine!
"Reduce the dose of the drug and do three more experiments, one-half, one-fourth and one-eighth of the original dose, and then observe the experimental results. If the immune system still works normally, then reduce it to One-sixteenth and one-thirty-two!”
"The experimental status of these people is very good. Apart from other things, I can't compare with their concentration. When I was tearing graphene apart before, I was not so focused. No wonder they can enter Tsinghua University and become top academics. I tried my best to get tested at the county testing station.”
Zhang Wei let out a long sigh and decided not to disturb the three graduate students. He quietly exited the laboratory.
"Even if he has put on weight for the winter, he will definitely not have many experimental tasks recently. It is the end of the year, and the projects in the Department of Physics are almost completed, and the plan for next year has also been submitted, so Professor Fang took annual leave. Went to the North Sea Fleet to see his son.
"Have you ever felt that Chen Ming has been acting weird recently?" Ye Haotian asked.
It is said that Professor Fang's son has found a partner, a female military doctor who was newly assigned to their army. Professor Fang went over to see his future daughter-in-law, and also met the girl's parents. If it was suitable, the marriage would probably be settled. . "
Ye Haotian is indeed a master of Sheniu. He is well-informed and even knows things about the physics department so clearly.
"If Professor Fang marries his daughter-in-law, even though the couple is stationed at the North Sea Fleet, he will probably come back to have a banquet? Then I will have to follow the family! How much money do people in the capital generally give?" Zhang Wei Said subconsciously.
"That's not the point! The point is that Professor Fang is not here, the Department of Physics doesn't have any big projects, and Chen Ming doesn't have that many experiments to do! But this guy still leaves early and comes back late, and doesn't see anyone every day. Don't you think it's strange!"
"I almost forgot, we were discussing Chen Ming! No, you were the one who started the topic of Professor Fang finding his daughter-in-law!"
Then Zhang Wei thought about it carefully. If Ye Haotian said it, the autistic person's recent behavior was really weird.
This guy doesn't have many friends and has no need for social interaction. In addition to eating and sleeping, he usually goes to the physics department to do experiments, so he will only appear in three places, the dormitory, the cafeteria, and the physics department laboratory.
When there was no experiment, autistic people did not go back to the dormitory to isolate themselves. It was really abnormal.
Ye Haotian continued: "There is another thing, which is also very strange. When I came back, didn't I bring a box of beer to Chen Ming? But the next day I found that the box of beer was missing half of it!"
"Chen Ming drank half a box of beer in one day?"
"With his drinking capacity, do you think it's possible? Did you hear the theory of relativity last night?"
Zhang Wei shook his head: "I haven't heard of the theory of relativity recently!"
The fact that he has not heard the theory of relativity means that the autistic person has not been drunk recently, and with his drinking capacity, how can he not be drunk with half a box of beer! "That's why I said that Chen Ming has been acting weird recently! I was wondering if he might have been abducted into some bad element group? For example, he was tricked into joining some cult organization!" Ye Haotian said.
"What are you thinking about? You have to believe in the security level of our country. Moreover, he is autistic and can't speak clearly. Why do you expect him to preach? What does the cult organization want him to do!"
"All he has in his mind is quantum physics, and he might be able to build a nuclear bomb!" Ye Haotian said.
"Well, you have a big imagination and have watched too many science fiction movies."
"Anyway, I want to investigate!" Ye Haotian was possessed by Holmes.
"How to investigate?"
"Follow me!"
"The love is possessed by Kogoro Mori!" Zhang Wei let out a long sigh.
Ye Haotian continued: "I asked my senior brother from the Physics Department. Chen Ming was still in the Physics Department just now. I plan to go over now and wait for Chen Ming to come out at the door of the Physics Department, and then follow him to see what he is doing. !”
"How about I go with you? Let's call Xiong Xinxin. She is better at fighting. If we encounter criminals, there will be someone to protect us!" Zhang Wei said.
"You have grown 1.8 meters tall for nothing. Do you still need a woman to protect you?" Ye Haotian gave a look of disdain and then said: "If you really encounter a criminal, you must call the police first! All your safety education is in vain. learned!"
The two of them were chatting while walking out of the dormitory. When they reached the door, they happened to see the pretender coming back from outside with a stack of A4 paper in his hand.
"Brother, I listened to you and posted the "Tomb Robber Diary" I wrote on the Qidian Chinese website. Guess what, they want to sign a contract with me! I typed out the contract. You can help me later. Take a look!" The pretender raised the stack of A4 paper in his hand.
"I'll show it to you when I get back in the evening. I don't have time now, I'm busy!" Zhang Wei replied.
"What's so good about it?" The pretender's curiosity was instantly piqued.
"Brother Haotian wants to be Maori Kogoro!" Zhang Wei said.
"Brother Haotian is Kogoro Mori, and you are Conan for Viagra. Are you still missing Officer Megure? I can do it! Brother Maori, Conan-san, let's go!"
"Conan is a generation younger than Officer Megure. Are you trying to take advantage of me? Does this make you act ethically?"
"He is also taking advantage of me. He calls me Brother Moori Kogoro! I said Xiaolu, you really know how to choose roles, especially those with seniority!"
The three of them were playing around and arrived at the door of the Physics Department.
Ye Haotian took out his mobile phone, sent a text message, and then said, "The senior brother from the physics department said that Chen Ming is coming downstairs. Let's hide quickly and don't let him see it."
The three people immediately hid in the corner.
Not long after, the autistic man indeed appeared in the three people's field of vision.
The autistic man took out his cell phone, glanced at the content on it, and then walked directly south.
"The dormitory is in the north. Chen Ming is walking south. It seems he doesn't plan to return to the dormitory." Ye Haotian said.
The three people followed from a distance, and saw the autistic man walking towards the east again after reaching the intersection.
"Is the gymnasium to the east? Brother specimen wants to do some exercise?" Lu Yunxiang asked.
"You say he is a specimen, how can he still do sports! I occasionally play ball. Have you ever seen him do sports?" Zhang Wei responded.
However, when he got to the basketball court, the autistic man turned south again.
"To the south is the main building, which is the office area! Chen Ming doesn't know the leaders in the school. What is he doing there?" Ye Haotian said.
"Don't forget, if you go further along the main building, you will leave the school. Maybe he will leave the school. If the criminal is outside the school, it will be really dangerous for us to follow him. It is still too late to call Xiong Xinxin over now." Zhang Wei said.
While the two were talking, they saw the autistic man turn again and walk into the large green area behind the main building.
It is winter at this time, and the grass in the green area has turned yellow, with only a few pines still retaining some green.
"It's winter, and there's not much scenery to see inside. What's Chen Ming doing there?"
"Brother Specimen is in a hurry to urinate and want to go in for convenience?"
"What are you thinking about? Which building nearby doesn't have a bathroom? Besides, Chen Ming is just autistic, not that shabby!"
While the three of them were talking, the dog approached furtively.
From a distance, I could only see Chen Ming sitting under a tree, but he was not alone.
Next to Chen Ming, there was a girl wearing a light yellow down jacket and a red scarf sitting. The two were holding hands and leaning against each other!
At this moment, the three of them couldn't believe their eyes.
Shocking big melon!
An autistic person is actually in love!
(End of this chapter)
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