Chapter 204 Eat a Fat Man
Professor Shi looked at the paper handed over by Zhang Wei with a look of surprise on his face.

The paper has been written, which proves that the scientific research project has been completed. But it only took a few days, how could the project be completed?

After looking at the title of the paper, the phrase "induced pluripotent stem cells" came to Professor Shi's eyes. The emergence of the phrase "induced pluripotent stem cells" also means that the project has achieved results.

Professor Shi quickly opened the paper. He skipped the beginning and middle and went straight to the final conclusion.

"IPS cells differentiated into nerve and muscle tissue? It really succeeded!"

Surprised, Professor Shi also took a breath of air. This was used to replace embryonic stem cells. Zhang Wei made it in such a short time.

"Brother, how about I briefly report the experimental steps of the project!" Zhang Wei gave a general introduction to the experimental process.

"Zhang Wei, are all your projects so smooth? Just do it step by step, and the results will be achieved? Are there any obstacles in the middle?" Professor Shi asked curiously.

"What? You still expect me to encounter obstacles in my experiment!" Zhang Wei asked with a smile.

"That's not what I mean. What I mean is that when we usually do experiments, we always have to go through some processes of failure, and then we summarize the experience through failures, eliminate wrong options, and finally obtain the experimental results!" Professor Shi explained.

"Worship God?" Professor Shi was stunned again, wondering what kind of trick this was!
"Every walk of life has a patron saint. For example, those who raise silkworms worship Leizu, those who do business worship Zhao Gongming, those who make paper worship Cai Lun, those who make pens worship Mengtian, those who make wine worship Dukang, those who make numbers worship Stove King, and fishermen worship Mazu. The craftsman worships Lu Ban, the tea fryer worships Lu Yu, the actor worships Li Longji, the crosstalk speaker worships Dongfang Shuo, and the two-person singer worships senior brother..."

As for fruits, I prepared apples, oranges and grapes. This orange tastes great and I eat one every afternoon. As for nuts, there are pecans, almonds, macadamia nuts and black walnuts, and dried fruits include dried cranberries and dried cherries.

"Do you still want to take the formal route? Let alone Tsinghua University. Even if you want to come to Princeton, you don't need to start as an assistant professor. I guess the school committee will at least give you an assistant professor."

The drinks include coffee, black tea and green tea. I also prepared a bottle of 99 red wine and authentic Kentucky corn whiskey! I originally wanted to buy a few bottles of beer..."

"It turns out you all did this experiment!" Zhang Wei showed an expression of sudden realization.

Another example is that in the genome used by Zhang Wei, c-Myc is an oncogene. If other genes can be used to replace c-Myc, or nucleoside modification methods can be used to edit c-Myc so that it loses its carcinogenicity, IPS can also be improved. Cell safety.

"Nagasaki? Eat fat?"

At this stage, Mr. Zhang Wei found the genome, induced IPS cells, and demonstrated the potential totipotency of IPS cells through immunodeficient mice.

"Sir Zhang, I have prepared food and drinks to welcome the gods!"

"I'm not. I've never failed in my experiments!"

"Wait a minute, according to what you said, do we do scientific research with Darwin, Newton, or Einstein? If you think these are young, should we worship Archimedes and Aristotle?"

Professor Shi repeated it and understood what Zhang Wei was talking about.

"That's it! Except for Sam, I really have no one to use. If you are unlucky, you can only use him. He is an assistant professor after all, and his academic ability is still very good. If you change it to someone with average academic ability, , I’m not worried either. And I took him with me to worship God.”

What a metaphor! Just for eating fat in Nagasaki, I have to give you a thumbs up!
……

"Didn't I drop out of Tsinghua University? Do I have to find a way to go back? The formal way to go to university is not to take the college entrance examination!" Zhang Wei replied with a smile.

"The main reason is that you can't find statues of other gods in the second-hand markets in the United States. Besides, Mr. Guan's righteousness and Bo Yuntian are all the fault of others, so why should he help his brother!"

"Assistant professors basically have their own projects, or are working in other project groups, so there is no extra for you."

Sam looked at his watch: "Yeah, it's afternoon now, just in time for afternoon tea!"

"Okay, let me read this paper carefully and give you an answer." Professor Shi paused for a moment, then asked: "Then what happened to what you just said about asking for leave to return to China to take the college entrance examination?"

He is a genius scholar who has produced Nobel Prize-level results at the age of twenty. You, an ordinary scientist, can't compete with a genius!

"Don't rush for manpower, let's wait until I come back from China! IPS cells have huge potential, and the research on IPS cells cannot be completed in a day or two.

However, if you want to perfectly replace embryonic stem cells, you need to verify the other capabilities of IPS cells, which requires a series of follow-up experiments.

This is only the development and research of IPS cells themselves. There are countless ways to use IPS cells for medical research to treat various diseases.

"The national conditions are different. Americans can get into good universities with letters of recommendation. It is not easy for domestic college students to pass the Qingbei exam. I can't be special!" Zhang Wei continued to talk nonsense.

"I asked Sam to worship Mr. Guan."

"I asked you to prepare tributes, and you made me a table of afternoon tea?" Zhang Wei interrupted Sam's introduction.

"To help my brother? Isn't this still a favor?" Professor Shi muttered in a low voice, and then continued to ask: "Also, I hear what you mean, the follow-up scientific research ideas are already in place? Do we need additional funds?
If I want to increase funds, it is not impossible. I have to wait until this paper is published and the results are obtained, and I can legitimately report to the school! "

"Second Master Guan? Isn't he the God of Wealth? Is he still in charge of scientific research? I remember that I only worship Second Master Guan when I do it!"

"I really don't understand the thinking of you young people." Professor Shi shook his head helplessly and continued:
"Also, what is going on with that Sam? I told you before that this guy has some bad luck and has failed three projects in a row. If you let him be responsible for the subsequent experiments, you are not afraid that the project will be ruined by him again. ?”

After listening to Zhang Wei's introduction, Professor Shi fell into a brief silence. After a while, he slowly digested what Zhang Wei said, and then he said:
"Listen to what you said, you are planning to play a big game! If I finish studying what you said, your team will not be enough. I will have to add more people to you. But my population here is also a bit stretched, you It’s really going to be a problem for me!”

"you are not?"

“I prepared cheesecake, biscuits, cookies, blueberry tarts, apple pie, brownies, plus cheese sandwiches and appetizer salads.

"There should be no need for additional funds before I come back. The money you gave me before has not been used up, and it is enough to do a few experiments." Zhang Wei paused, and then began to introduce the follow-up research on IPS cells.

Looking at Zhang Wei's awesome expression, Professor Shi was immediately discouraged.

In addition, there is still a lot that can be studied regarding the generation of IPS cells. For example, Zhang Wei is currently using viruses as gene vectors to inject into host cells. In the future, he can study not using viral vectors, and the safety of IPS cells will be greatly improved.

Zhang Wei moved the statue of Brother Guan to Sam's office.

Sure enough, when I arrived at Sam's office, I saw a table full of food and drinks on his desk.

Zhang Wei was immediately speechless: "Okay, since we have prepared so much, don't waste it. We will take it to the lounge later and let's all eat together!"

Scientific research is done step by step and slowly! I'm not Nagasaki, so I can't eat a fat man in one sitting! "Zhang Wei said.

"How about you arrange an obedient assistant professor for me?"

"Food? Drinks?" Zhang Wei's heart suddenly tightened. He felt that this did not seem to be a very reliable description.

"Isn't it for the gods to eat?"

"The gods can't eat so much, so I'll give it to you." Zhang Wei shook his head helplessly, and then asked: "Where should I place the statue of Master Guan?"

"It's on the cabinet over there. I cleaned out a special space." Sam pointed to a location.

Zhang Wei turned around and saw a garland placed on the cabinet!
"This..." Zhang Wei hesitated for a few seconds before placing the statue of Master Guan up.

Sam, with a pious look on his face, picked up the garland and put it directly around Mr. Guan's neck.

"I guessed that this wreath was used like this!" Zhang Wei complained in his heart.

There is something called a Christmas wreath in the West. According to traditional Western customs, wreaths are hung on the door during Christmas to ward off evil spirits, just like the Chinese door god.

In many religious ceremonies, garlands are also used. For example, in churches, garlands are often seen as decorations.

At this moment, Sam has obviously moved Western religious rituals here.

However, what Zhang Wei didn't expect was that wearing a garland was only the first step. Sam didn't know where he came from, and took out a metal goblet, and then placed it next to the statue of Guan Erye.

"What is this? Does it serve wine?" Zhang Wei asked subconsciously.

"This is the Holy Grail!" Sam replied with a serious face. "Holy Grail?" Zhang Wei suddenly stood on the spot.

You might as well place a Holy Grail for Mr. Guan instead of a copy of "Spring and Autumn"!

Sam showed a triumphant expression and said, "How's it going? I'm well prepared!"

……

After arranging things in the United States, Zhang Wei flew back to China to prepare for the 2005 college entrance examination.

But before that, Zhang Wei went back to Tsingta University and reported to Principal Gu the situation in the United States.

"You mean, you have found a substitute for embryonic stem cells in such a short period of time?" Principal Gu looked surprised.

Although Principal Gu is not a biology major, he still has basic biological knowledge. He knows very well what substitutes for embryonic stem cells mean.

Zhang Wei continued: "I obtained this kind of cells through gene induction, so I named them induced pluripotent stem cells, or IPS cells for short."

"Can embryonic stem cells be completely replaced?" Principal Gu asked.

"In terms of biological characteristics and protein expression, it can replace embryonic stem cells. As for other genetic modifications, it still needs to be verified, but I think there should be no problem."

"Oh, what a pity!" President Gu suddenly showed a regretful expression, and continued: "Such good scientific research results should be done at Tsinghua University! Princeton University is cheaper!
In this case, the intellectual property rights of IPS cells are all owned by Princeton University. If we want to use IPS cells for scientific research later, we may be blocked by the Americans. "

"Principal, don't worry, there is not just one way to induce IPS cells!" Zhang Wei said calmly.

Principal Gu's eyes suddenly lit up: "Have you thought of other methods?"

"In scientific research, there will never be only one way! Principal, don't worry, I will definitely leave the better method to us Chinese people for our own use. Of course, it will not be free for Americans."

"Seeing that you are so confident, I feel relieved." Principal Gu breathed a sigh of relief, and then asked: "By the way, before you left, you said you wanted Professor Shi to return to Tsinghua University. How was the discussion? ?”

"Professor Shi's contract with Princeton University will not end until 2008, so he will not be able to come back until 2008."

"There are still three years. Three years can be said quickly, in a blink of an eye." Principal Gu nodded. As long as Professor Shi can come back, Tsingta University can afford to wait for three years.

Zhang Wei continued: "Principal, my thesis this time will be published as soon as June. This is the first bargaining chip we have bet on. You must make good use of this bargaining chip then!"

"Don't worry, I've already made arrangements with the Publicity Department. As soon as your paper is published, we will immediately put a big star in the media!"

"Then I'll be fine. I'm taking the evening flight back to Qinhai. The college entrance examination is in a week. I have to review quickly." Zhang Wei continued.

"College entrance examination? What kind of college entrance examination are you taking? Restoring your student status is not a matter of a word from me. Aren't you just causing trouble for yourself in your idleness?" Principal Gu couldn't help but complain.

"Principal, aren't I trying to protect the fairness of our college entrance examination? If I become famous later and people find out that Zhang Wei is a well-connected guy and got into Tsinghua University through the principal's connections, then my personality will collapse! "

"You scored 750 in the college entrance examination and returned it twice. Who has ever seen a relationship household with a score of 750? If you really want someone with a score of 750, I want as many as you can get!"

……

It’s the college entrance examination time again, and this is Zhang Wei’s third time taking the college entrance examination. But this time, Zhang Wei took the liberal arts exam.

When the arts and sciences were divided into subjects, the reason why Zhang Wei chose science was actually not because he was poor in liberal arts. On the contrary, his grades in liberal arts were quite good, especially geography and history. He worked hard to get a score of 90 or above, but he was a little behind in politics. Passed the passing mark.

In terms of science, Zhang Wei's grades in the three subjects of physics, chemistry, and biology are all good. His biology test score is over 90, and physical chemistry is also above 80, with no shortcomings. It was also because of his good grades in biology that he chose the sinkhole major of bioengineering.

Such results, placed in other provinces, would definitely put him at the top of the list of academics. However, in the four provinces of Shanhe, where the college entrance examination is extremely difficult, he only scored 250 points in Science and Comprehensive Science, which is at the second-level level. It is difficult to stand in the first-tier.

Especially in the easternmost province, the undergraduate score line may not be the highest, but the number of candidates with high scores is the most.

This is extremely unfriendly to candidates with high scores. There are only a few good schools and good majors. If your score is higher, the competition will become more intense. If you are not careful, you will fall into the adjustment and choose a major that you do not want.

On the contrary, candidates with lower grades can enter good majors even though their schools are worse.

How did Teacher Zhang Xuefeng choose between the Tiankeng major in a good school and the trump major in an ordinary school?

After walking out of the examination room, Zhang Wei went to the drugstore as usual and saw the aunt selling medicine again.

"Auntie, do you still remember me?"

"You are Kaiselu!" The medicine seller recognized Zhang Wei at a glance.

"Auntie, you still can't speak!" Zhang Wei sighed helplessly.

The aunt showed an excited expression, as if she had met her childhood best friend, and said in surprise: "Are you constipated again? Did you take the college entrance examination again? Did you fail the entrance examination last year?"

"Isn't that right? Auntie, I remember you said last year that if I take the exam again this year, you would give me Kaiselu as a gift!"

"Send it to me! I will give it to you for sure! Even though you have passed the exam for the third year, your aunt has to give it to you too. Oh, this poor kid!"

The aunt muttered, took out a few bottles of cork oil from the counter, and placed them in front of Zhang Wei. Then she hesitated, took another bottle of fish oil, and placed them on the counter.

"Auntie, this bottle is golden, or a small capsule. It doesn't seem to be Kaiselu, right?"

"Young man, this bottle is fish oil. My aunt gave it to you. This fish oil can nourish your brain."

"Do I look like I'm not very smart?"

"You've been taking the exam for three years! You still think you're smart!" The aunt's mouth was still rude. She continued: "Young man, if you don't listen to my advice, stop taking the exam and go to a technical school to learn a skill. , can also support oneself.

Didn’t it say in the advertisement, which company has the best excavator technology? Find Lanxiang in Shandong, China! Where is the best place to learn to be a chef and pastry chef? Come to New Oriental Cooking School! "

"Auntie, you know the slogan so well, it seems you are a loyal viewer of Shandong Satellite TV."

Zhang Wei said, picked up the bottle of fish oil, looked at it, and then said: "This bottle of fish oil must be quite expensive, how much does it cost, or I'd better give you the money!"

"You don't have to give me any money, I told you I would give it to you!" the aunt said grandly.

"When we open our doors for business, we can't let you do business at a loss! I took the Kaiseilu for nothing, and I have to pay for the fish oil."

"It's really not necessary. The fish oil is about to expire anyway, so you can just take it!"

"Is it about to expire?" Zhang Wei looked at the date. It expired on June 6th, and there were still ten days left.

"This aunt is really good at giving favors." Zhang Wei complained in his heart.

The aunt continued: "Actually, it's okay if it's a little expired. My Doudou eats expired fish oil."

"It's best not to eat things that have exceeded their shelf life, as they may be harmful to your health." Zhang Wei advised.

"It's okay. My Doudou has been eating expired fish oil. After eating it, not only did the hair stop falling, but the hair became shinier and brighter!"

"Shedding hair?"

"Short-haired dogs generally shed hair, twice a year for six months at a time. After taking this fish oil, they are much better!"

Zhang Wei looked at the bottle of fish oil in his hand, and his auntie sprinkled it with dog food!

(End of this chapter)

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