Siheyuan: I eat melons while doing scientific research

Chapter 1235 A Small Crack (4k, 5k more)

Looking at the expression of the leader of the 11th Ministry of Machinery, the leader of the 17th Ministry of Machinery laughed awkwardly and said, "It's not usually like this. This is special."

Well, I can see that it is quite special, but it is worth it.

He didn't know what the situation of Commissioner Gao Zhendong was in the 17th Ministry of Machine Building, but judging from the fact that just showing up on his side could cause such a big fuss, wouldn't it be even more serious if he did it on someone else's own territory?

Seventeenth Ministry of Machinery: Oh, you guessed it right.
-
Gao Zhendong is taking a break from his busy schedule, but his wife is extremely busy.

For this, she even sent Yan Zhibu Yu back to her grandmother's house. This was a real return to her grandmother's house.

"…Our combination of β-lactamase inhibitor and antibiotic has been proven to be effective against methicillin-resistant Staphylococcus aureus and other drug-resistant bacteria through various controlled, randomized, and repeated experiments, while also implementing the principle of balance throughout the above experiments…"

In a meeting room of the Medical and Health Commission, a clear voice was giving a report in a rhythmic manner.

The person making the report at this time was Lou Xiao'e herself. In the words of Professor Qi and others, this was called a good image and good temperament, which was conducive to the smooth progress of the reporting process.

And from another perspective, as the author of the "Concise Manual for Primary Care Doctors" and a March 8th Red Flag Bearer and advanced worker in the Medical and Health Commission system, Lou Xiao'e's report also seemed to be more taken seriously.

The methicillin-resistant Staphylococcus aureus reported by Lou Xiao'e has actually existed for a long time, so there is no shortage of similar patients in China, and a large number of samples have been accumulated in the experiments over this period of time.

However, we don't have much research on clinical trials of drugs at present. One reason is that there are too few talented people in this field. Fortunately, there are comrades who have returned from overseas and have done some research in this area.

Another problem is that we don’t have that many new drugs to do this, so naturally there isn’t much research and practice in this area. In fact, it wasn’t until the 80s that we started to systematically start in this area.

Today's meeting is not a report on project completion and acceptance, but merely a progress report. It is equivalent to informing the Medical and Health Commission of the matter, summarizing the experience, and implementing the next steps.

After all, this is one of the few drugs that follows the Citi FDA process. The FDA just lost face because of the side effects of the drug, so it was determined to come up with a good set of things.

After listening to the report, an expert showed a happy look on his face, but also thought: "Well, from the current situation of domestic research and practice, your clinical trials are relatively solid. Let's not talk about whether your drug is effective or not, but at least one thing is that the process is working. From the perspective of clinical trial practice research, this is even more important than the drug itself."

The issue of drug-resistant bacteria is currently a thorny one, but not serious. After all, the number of cases occurring is small. In this case, this research is important but not urgent. In fact, even in the 21st century, drug-resistant infections are generally not very common.

Therefore, using this drug to run through the clinical drug trial process has become something that some experts and scholars in the Medical and Health Commission who are very interested in the standardized conduct of drug clinical trials have attached great importance to.

"Well, yes. In addition to studying the drug itself, we also pay great attention to the clinical trial process and have been strictly following the relevant requirements." Although Lou Xiao'e is still a graduate student, she has met many high-level leaders and experts. To put it bluntly, she sees them every day at home, so she is not stage fright at all.

"But I think you are still missing one thing." This expert returned from overseas and has done more research and thinking in this area than his domestic colleagues.

Lou Xiao'e picked up the pen and said, "Please go ahead."

This was a progress report, so she was even more relaxed. She remembered Gao Zhendong's instructions and wrote down whatever the expert said. She nodded as she wrote down the words, and said a few words like "um" and "OK" to show her utmost respect.

As for whether the experts' words will be implemented or not, we will have to wait and see.

However, what this expert said today is undoubtedly worth implementing.

"I think you should still join a double-blind trial and try to eliminate the influence of subjective will on the test results."

"Double-blind trial?" To be honest, Lou Xiao'e herself was not familiar with this aspect.

"Yes, the subjects, that is, the patients, and the researchers, that is, you, didn't know how to divide the control group and the experimental group. This matter should have been done earlier, but you were too quick and found the bacteria strains too easily, and I didn't react at all. I was still organizing the relevant information for you." At this point, the expert couldn't help laughing. It really was not these comrades' fault.

However, his words stunned Lou Xiao'e and the others, including Professor Qi. Only Lou Xiao'e was stunned, feeling sweet in her heart.

——It’s not that we are fast, it’s that my Zhendong is so good that even his luck is so good.

Everyone was puzzled, but Lou Xiaoe was still asking the question: "Why is this? In this way, won't the researchers be able to know the results?"

The expert smiled and said, "There is another hidden role here. You have played it before, but in this experiment, it has to be singled out, that is, the designer of the experiment. No one except the designer of the experiment knows how the experimental group and the control group are allocated. This can avoid the experimental results being affected by the placebo effect or observer bias to the greatest extent. Of course, the final result will be revealed to you."

The placebo effect is when patients are given some sugar pills, starch pills or the like and told that they are medicines. The patients think they have been treated and sometimes they can recover or their symptoms can be alleviated without taking any medicines. The human body is a complicated thing.

Not to mention observer bias.

The expert's words made the comrades feel magical, but after thinking about it carefully, they had to admire the scientific nature of this method.

It must be admitted that the Russians and American citizens in the 20s to 60s were quite capable.

Even when Lou Xiao'e returned home and told Gao Zhendong about this, she was still full of admiration, with an expression as if she had learned something new today.

Gao Zhendong was almost fully aware of this - if he knew nothing about it, there was no need to go look for it specifically, it would be such a waste, just follow the FDA and it would save time, effort, money and worry, Lou Xiaoe just needed to learn from him.

"Well, what they say makes sense, just follow it."

"Yeah, yeah, by the way, tomorrow is Sunday. Let's go shopping while the kids are at their parents' house. We haven't gone shopping together for a long time." Lou Xiao'e bit the tip of her chopsticks and quickly put the matter aside, thinking about things to play.

When Gao Zhendong heard this, he was like, oh, that's true, they are always busy. Although the couple has a good relationship, they rarely go out together. If his wife gives an order, he must satisfy her.

"Well, okay!" Gao Zhendong said without any bargaining.

So the next morning, the couple rode their bicycles out. It was a long time since Gao Zhendong had ridden a bicycle. If it weren't for other neighbors who would borrow his bicycle from time to time, the chain of his bicycle would have rusted. The bicycle chain rang happily in the chain box, and the couple walked toward the street following the crisp "ding-ding" sound of the bicycle bell.

The supply and marketing company was bustling with people. In those days, there was only one day off a week, Sunday, and both students and adults rushed to buy things on this day.

"Hey, that's strange. Radios don't even require tickets anymore." A member of the public looked at the latest announcement from the supply and marketing company with a look on his face as if he had seen a ghost.

"According to the notice from the higher authorities, from now until April 4, radios, tape recorders, radios and other commodities will no longer be supplied with tickets. Comrades may purchase them freely." The black handwriting on the bright red paper looked very fresh, and the ink that had not yet dried gave off a faint scent of ink.

Although tape recorders and radio players are newer products, the traditional reputation of the radio's "three turns and one ring" still exists, and people still only talk about it.

It seems that it has been relaxed, but not completely. There is a time limit. I guess they want to see if it can be sustained first. If there is no problem, then they will relax it completely. We are still relatively cautious about matters related to the lives of the people.

For the masses, it doesn’t matter whether it smells good or not, the radio is still the best.

Ordinarily, this is something to be happy about, but in the eyes of ordinary people, it is almost like seeing a ghost, too strange. You know, in their eyes, if bicycles are still productivity tools, then radios are definitely luxury goods.

Luxury goods don’t require tickets anymore?
There is already a long line in front of the counter selling radios. Hey, this is the only thing they are selling this weekend.

Although it was no longer supplied with tickets, the radio's reputation of "three turns and one ring" remained, and comrades felt that it would be better to buy it while it was still available and put it in their pockets, in case the policy changed again.

For the common people at that time, not many people could afford a black and white TV of RMB 4 to 500, but many comrades could still afford entertainment equipment such as radios and tape recorders that cost from a few dozen to over a hundred yuan.

Not to mention that there are some young girls and boys, or elderly people who have children of marriageable age, who all have an urgent need to get married.

When supplies were based on tickets, if you didn't have a radio when you got married you could say it was difficult to get radio tickets or industrial tickets, but now that supplies are open and you still don't have one, then you're really embarrassed.

"Give me one, give me one!"

"I came here first. What's wrong with you, comrade? It's not okay to cut in line."

"I'm in a hurry to catch the train. Look, the tickets are all here. Sir, please be kind and let me go for a moment. I'm sorry."

"Forget it, forget it. The young man is in a hurry to drive the car, so let him go."

"It's a good year, and I can buy a radio for free."

"That's right. Have you noticed that the company is giving out more bicycle tickets and the like?"

"..."

Gao Zhendong looked at this scene and felt very happy.

Since sufficient supply of materials has opened up a small gap in the development of consumer electronics such as radios, more breakthroughs will surely come.

This matter is mainly due to the strong performance of semiconductor factories such as 1274 and 1218. The output of small-scale semiconductor components such as transistors has been increasing rapidly. For uncomplicated electronic products such as radios, as long as the core raw materials are sufficient, the production speed will not be too fast.

If we talk about trouble, it is the movement of the player and tape recorder that is more troublesome. However, the defect of the player requiring a tape sound source and the relatively high price of the tape recorder make up for this part very well. Because the demand is not that strong, the supply and demand relationship is generally balanced.

Looking at Gao Zhendong's smile, Lou Xiao'e knew what he was thinking. After all, although she didn't understand, she knew that her lover had put in a lot of effort in this regard. The scene before her was the best compliment to him.

Lou Xiao'e took Gao Zhendong's hand, leaned her face on his shoulder, and walked forward leaning on him.

When passing by the watch counter, they both raised their Breguet watches at the same time, looked at each other, and their eyes were full of smiles.

"Biu~~~Biu~~~Biu~~~"

A slightly plump child, who could be considered a chubby kid in this era, walked past them. He was holding a plastic box in his hand and pressing it non-stop. He was concentrating intently and had no distractions.

A comrade in his thirties followed him and said, "Son, I promised to buy you a handheld game console if you get first place in the grade. But you must remember your promise to me, be moderate, don't get addicted, and don't spend all your time on it."

The little fat boy said without even raising his head: "Don't worry, Dad. I will only play for a few days. I will definitely not be vague about my winter vacation homework. When school starts, I will give it to you. I will play whenever you tell me to."

Gao Zhendong was dumbfounded when he saw this scene. Is it happening now? Should we ask the manufacturer to provide some "anti-addiction care" to the children?
Forget it, forget it. There were so many games in the previous life, but a top student didn’t necessarily become a poor student. It depends on yourself and your family’s cooperation in education. There’s nothing wrong with having a complete childhood.

I guess if he was really too addicted, his parents wouldn't mind making his childhood "more complete".

Thinking of this, Gao Zhendong missed the 800-in-1 arcade machine in the living room of his previous life. Although those games were old, they were really fun.

Lou Xiao'e pulled Gao Zhendong and avoided a pillar.

I am in a daze again. Our Zhendong is good in every way except this one problem. It seems that it is not a big problem? Forget it, I won't change it. I just need to pay attention to it and don't let it bump into my head.

"Comrade, would you like to see the new Dacron material? It's blue, crisp and cool. This man will look absolutely amazing when he puts it on."

Perhaps the cheerful scene infected everyone, the salesperson from the supply and marketing company actually took the initiative to recommend fabrics to the couple, with no intention of scolding or beating the customers. Perhaps it was because he liked Gao Zhendong and his wife, the man was handsome and the woman was pretty, and he was happy to look at them.

(End of this chapter)