Siheyuan: The prosperous era starting from being a doctor

Chapter 439: I got the chance to leave my name in history

As early as when the 'Human Genome Project' was being prepared.

In fact, many people hold opposing views.

Their reason is that domestic economic and industrial development still requires a lot of funds.

The domestic market is relatively short of supplies.

These funds can be used to develop the economy and industry while improving the living standards of residents.

It won't be too late to launch the "Human Genome Project" when conditions are good and financial resources are sufficient. Anyway, foreign countries have no idea about it now.

At present, the domestic level in this industry is already far ahead.

It won’t be too late to implement the plan once the economy develops.

At last.

Although it was decided to launch the Human Genome Project as soon as possible, the superiors were also full of worries.

Afraid that something unexpected might happen in the middle.

After all, when the "Big Mushroom" was being developed, many people suggested postponing the process and developing the economy first.

and so.

The superior leader discussed the matter with Wang Mengde.

Let's see if we can produce some good results at the beginning of the Human Genome Project so that those who oppose it can see them.

Wang Mengde thought about it carefully and then came up with the research direction of cellular autophagy.

Later studies on cellular autophagy have resulted in several Nobel Prize winners in Physiology or Medicine, and even a Nobel Prize winner in Chemistry.

"Comrade Wang Mengde, you are here.

Good news, the research project led by you has produced a result in the field of cellular autophagy."

Seeing Wang Mengde walk into the conference room, the superior leader quickly waved and said happily.

The superiors had not expected that within less than a year of the establishment of the Human Genome Project, such great results would be achieved.

When people from the Genome Project Institute first reported it to him, they didn't take it too seriously, thinking it was just an ordinary research discovery.

Only after later researchers explained that this result could be a Nobel Prize-level discovery did he take it seriously.

So he hurriedly summoned Wang Mengde and others to go to the research institute to confirm it.

"Leader, this is indeed good news. This result may cause a sensation in the scientific research community around the world.

In two years, a foreign scientist will win the Nobel Prize in Physiology or Medicine for his research on cellular autophagy.

It is a good opportunity for our research results to attract the attention of the scientific research community around the world, and we may even win a Nobel Prize in Medicine in the future.”

Wang Mengde also said excitedly.

He is fully aware of all the research projects at the Genome Project Institute.

Even the progress will be reported to him on time.

After all, he is the chief technical director.

So when his superior leader told him about the results just now, he roughly guessed that aspect.

We also know in which direction the breakthrough has been made.

“Haha, everyone has worked hard during this period.

Once this result is confirmed, I will give credit to everyone."

The superior leader couldn't help but smile. After he said something to everyone, he said to Wang Mengde:
"Comrade Wang Mengde, after the meeting, I will need you to go and confirm it in person. The results of the test cannot be wrong.

By the way, you just said that in two years, someone will win the Nobel Prize for their research on 'autophagy'. Is this news true and reliable?"

It’s no wonder that the higher-ups are concerned.

It is true that Nobel-related awards have such a huge impact internationally.

domestic.

Apart from the Chinese, Wang Mengde is the only Chinese who has won the Nobel Prize in Medicine.

then.

The domestic people's self-confidence has been raised to a new level, which has completely shattered the idea that the domestic technology is backward and cannot be caught up even in a hundred years.

Internationally.

China's image has also changed in the minds of many foreigners.

Especially the scientific community.

With the rise of Wang Mengde and his continuous achievements.

This has aroused the curiosity of many people about China.

At the same time, I also developed a good impression.

This is something that a lot of money can't buy.

Because of this incident, the relevant departments mentioned it many times in front of their superiors and praised Wang Mengde.

"Leader, I received an invitation letter from the Nobel Prize Committee at the end of last year.

They invited me to rank and score some of the scientific research results nominated for the Nobel Prize, and to recommend better achievements.”

Wang Mengde explained with a smile:
“At that time, I saw an achievement in the nomination, which was about ‘cellular autophagy’, and he discovered ‘lysosomes and peroxisomes’.

This is a discovery that connects the previous and the next, and it is of extraordinary significance. It is far superior to the achievements of others.

If he doesn’t win the Nobel Prize in Physiology or Medicine next year, he will definitely win the prize the year after.”

As the world's most recognized and prestigious medical scientist, even if many people don't want to see it, they have to admit it.

Without Wang Mengde's participation, the selection of the Nobel Prize in Physiology or Medicine would not be so authoritative.

and so.

Starting last year, the Nobel Prize Committee made a decision that, unless unexpected events occur, Wang Mengde's opinion will be sought in the selection of the Nobel Prize in Physiology or Medicine.

And his opinion will be decisive.

In fact, most people in the committee do not want to give the decision-making power to a Chinese.

But there is no way, because Wang Mengde has achieved more and more research results over the years.

He has made outstanding contributions to world medicine.

Now in the world, except for China, almost one-fifth of the population is using various medicines or vaccines developed by Wang Mengde.

His influence is too great.

Those people had to compromise.

"Since that's what you think, then it's basically true."

After listening to his explanation, the superior leader smiled and nodded.

"By the way, aren't the two achievements you developed previously, the painkiller and the synthetic bovine insulin, said to be worthy of the Nobel Prize in Physiology or Medicine?

Is there any news recently? "

"If you had taken out these two achievements, that person probably wouldn't have had a chance to succeed."

The superiors particularly hope that Wang Mengde can win some important international honors while he is still working in the health and family planning system.

If he wins another Nobel Prize in Physiology or Medicine, the health department and he will get the attention of the higher-ups.

"For some special reasons, the Nobel Committee has become more cautious over the years.

It takes more time to test an achievement. For example, just after an award was presented, problems arose with the achievement not long after.

Therefore, under normal circumstances, it takes about ten years, or even longer, before a nomination is possible.”

Wang Mengde briefly introduced the Tao.

This is all caused by the frontal lobe surgery.

After that incident, the global scientific community was in an uproar, and the Nobel Prize has been criticized to this day.

therefore.

Over the years, the Nobel Committee has been undergoing reforms, and lengthening the timeline from research results to winning the prize is a way to avoid any unexpected events from happening again.

Wang Mengde can also be considered an indirect "victim".

Otherwise, with his achievements in painkillers and synthetic bovine insulin, he would have won one or two Nobel Prizes in Physiology or Medicine. But he didn't care.

Anyway, even though artificial bovine insulin has competitors, it still occupies more than 80% of the international market.

After the price dropped, foreign exchange earnings did decrease a lot.

As for painkillers, this one is awesome.

Now, women all over the world will use this medicine during childbirth as long as they have the conditions.

According to statistics from the World Health Organization, this drug can not only reduce the pain of childbirth for mothers, but also significantly reduce the mortality rate.

Many women's organizations are preparing to honor Wang Mengde.

He also earned the nickname "Friend of Women".

In addition, it is used in various places such as surgery and trauma.

And the most special effect is that it can reduce the pain of patients addicted to "leaves" and help them quit this evil thing that makes normal people shudder and destroys their families.

In fact, just relying on this one function, it can crush most of the inventions in the world.

No matter which year in the future, when Wang Mengde is nominated for the Nobel Prize in Physiology or Medicine for this achievement, everyone else will be just a foil.

"So that's what happened."

The superior leader suddenly realized.

He hesitated for a moment, then continued:
"Whether or not we win the Nobel Prize in Physiology or Medicine, or whether we win it in the future, it will not affect our contribution to the world and humanity."

After a brief meeting.

After his superiors left, Wang Mengde followed other researchers to the laboratory.

“Director Wang, based on the research direction you gave us, we have conducted in-depth research on the process of protein degradation in the vacuole.

Because yeast cells are too small, it is not easy to see their internal structure under the most advanced microscopes currently available.

So at first it was not certain whether autophagy also occurred in yeast cells.

But after your suggestion and the hard work of all of us, we found that when task autophagy occurs...

It will be visible under a microscope.”

“Guided by this theory, we conducted research and improvement work.

The main thing is to first cultivate yeast cells that lack vacuolar degradation enzymes due to mutations, and then stimulate autophagy by starving the cells. "

A project director, standing beside Wang Mengde, explained excitedly.

As one of the few researchers in China who has conducted in-depth research on genes, he deeply understands how important the results of this experiment are.

In terms of honor.

This research result is enough for one or two people to win the Nobel Prize in Physiology or Medicine in the future.

In terms of practicality.

It can be applied to some major diseases in the future.

For example, Parkinson's disease, severe diabetes, etc.

"good.

I didn't expect you to get results so quickly.

But this is just the first step, although it is the most important step, there is still a lot to do next.

The first step was to identify the first genes that were critical for autophagy.

Then, in the research, we will have a detailed understanding of the efficacy and function of the proteins encoded by these genes.”

Wang Mengde praised everyone and then made a suggestion:

"Once we have the results, we will be able to roughly understand the crucial mechanisms in our cells."

"Yes, Director Wang, we will definitely conduct in-depth research according to the research direction and suggestions you gave us."

The seven or eight people present were all excited and quickly agreed.

to be frank.

It was because they met Wang Mengde. Otherwise, relying on their own abilities, it would take at least five years of research before they could have a chance of producing some results.

And now.

It only took them more than half a year to break through an important "barrier".

From now on, there is only a smooth road ahead.

Everyone believes that as long as we move in this direction, good results will soon appear.

This will be their chance to leave their names in history.

Spent a whole day at the Genomic Opportunity Institute.

During this day, Wang Mengde not only guided the work of more than a dozen project teams, but also led everyone to solve several obstacles.

At the same time, we also learned about the current progress of the "Human Genome Project".

All I can say is that this plan is too big.

Over more than half a year, a huge amount of manpower, material resources and money were spent.

Now even the head hasn't been opened.

Future investment will be a bottomless pit, and in terms of results, if Wang Mengde had not taken out "cellular autophagy" for research, it might not be possible to produce any major results even after ten years.

At that time, those involved in this plan will be under tremendous pressure.

But things are different now.

According to Wang Mengde's estimation, a paper on the research on cellular autophagy can be published by the middle of next year at the latest.

Once researchers around the world learned about the key mechanisms of cellular autophagy, the research situation suddenly became clear.

The number of related papers published will also increase suddenly and significantly.

Bringing together the world's top scientific research forces.

Related research progress will be rapid.

And China will cut the biggest piece of this big cake.

Mid June.

The results of the postgraduate entrance examination in Traditional Chinese Medicine are finally out.

The names of Jiang Lin and Qian Tong appeared in fourth and sixth place respectively.

The tutor they applied for was Wang Mengde.

this day.

In a temporarily borrowed classroom at the Beijing College of Traditional Chinese Medicine.

Wang Mengde circled eight names with a brush.

These people will become his students in the next few years.

soon.

Jiang Lin, who lives in Beijing, was the first to receive the notice of admission.

“Ahhh, I was accepted, I was accepted.”

Jiang Lin did not hide his joy.

After receiving the admission letter from the postman, he was as excited as a child, dancing with joy.

"Son, what are you so happy about?"

At this time, his mother came in from outside and saw her son holding a piece of paper in his hand and laughing foolishly, so she asked curiously.

"Mom, I was admitted to graduate school. I will study with Professor Wang Mengde from now on."

Jiang Lin couldn't wait to tell his mother about this joy.

"Oh, son, you are amazing.

Is passing the postgraduate entrance exam the same as passing the imperial examination in ancient times?"

(End of this chapter)