A doctor who travels through two eras

Shen Guoming listened for a long time, and finally couldn't hold back any longer:
"What exactly is this cephalosporin you're talking about? We only know it's an antibiotic, but what are its functions and significance?"

Lin Sanqi said embarrassedly:

"Oops, I've gone off-topic. The cephalosporins I'm talking about can actually be seen as an upgraded version of penicillin. Their antibacterial spectrum is almost the same as penicillin, but they are more potent and have better efficacy. As you can see, I already have the finished drug."

After saying that, Lin Sanqi asked his secretary to open a cardboard box next to his feet and take out strips of capsules.

In the early 1960s, there were no oral antibiotics available.

(In reality, the first oral antibiotic, cephalexin, was not expected to be available overseas until 1968.)

Sulfonamides are in powder form, packaged in paper bags, which is very basic. Penicillin, on the other hand, is an injectable form and requires refrigerated transport, making administration very inconvenient.

The medicine blister pack that everyone received was packaged in a sealed plastic sheet. Just by looking at the packaging, everyone knew that a high-tech product had arrived.

Lin Sanqi then continued:

"This oral cephalosporin is more effective and convenient for patients to use. In the future, patients may not even need to go to the hospital if they have an infectious disease. They can just take a few pills at home. Isn't that convenient?"
Similarly, the medicine I'm using is more in line with our national conditions.

Currently, we have few hospitals, even fewer doctors, and a severe shortage of nurses specializing in injections. Moreover, even if we have syringes, sterilization is a major problem.

When I visited Shaanxi Province, I found that the provincial hospitals there also used iron pots to boil used glass syringes and metal needles before continuing to use them, without even soaking them in alcohol.

I know this is a last resort for the hospital, but everyone should know that improper disinfection can exacerbate cross-infection of various blood-borne infectious diseases, such as hepatitis and some sexually transmitted diseases.

Therefore, we must remember one principle: avoid using antibiotics whenever possible and avoid overuse. At the same time, oral administration should be preferred over injection for ease of administration.

Imagine this: in the future, a patient comes in for treatment, and you discover they have pneumonia or some other infection. Wouldn't it be more convenient and efficient to just give them a few strips of medicine and have them take it orally at regular intervals?

Shen Qiushui, a clinician, immediately brightened up upon hearing this:

"Yes, it's not only more convenient to use, but more importantly, it's easy to carry. For example, when I worked in Yunnan, there were mountains everywhere, and it was very inconvenient for ordinary people, including soldiers stationed in remote areas, to see a doctor."

Our doctors make regular rounds, but at most once a month. Many patients don't need just one treatment; once the doctor leaves, they can only wait to die because only professional doctors and nurses know how to administer injections.

Now that we have this oral medication, we can administer it according to the prescribed course of treatment.

Take this cefuroxime tablet, for example. I see it says one or two tablets at a time, twice a day. Even if the course of treatment is 5 days, in the past, unless a patient was extremely wealthy, they couldn't afford to go to the hospital for injections for 5 consecutive days.

Now that we have this medicine, as a doctor, I can prescribe 10 pills at a time, a 5-day supply. Patients recover more thoroughly, and the increased chance of recovery means a significant reduction in mortality. This is perfectly in line with our current national conditions; it's wonderful!

Everyone in the conference room started talking at once, clearly realizing the significant implications of the sudden emergence of oral cephalosporins.

It also solves the harsh conditions required for penicillin transportation, such as the need for low-temperature refrigeration and maintaining stability within 24 hours.

Given that there were very few refrigerators in China at that time, it was even more impossible to provide refrigerated transport vehicles.

This is also why penicillin is so expensive. It's hard for modern people to imagine that a bottle of penicillin costs as much as a small yellow croaker, and in inland areas it can even cost as much as a large yellow croaker. Even so, it's still hard to find a market for it.

This also explains why, during the War of Resistance against Japan, wounded anti-Japanese officers had to risk traveling to Shanghai for medical treatment, only to be betrayed and arrested by traitors.

Do you really think these soldiers are stupid? Don't they know that going to the Japanese headquarters is extremely dangerous?

But they had no choice; to save their lives, they had to go to big cities. Antibiotics, especially penicillin, were simply too difficult to transport to the rear areas.

Lin Sanqi then instructed Secretary Bai to distribute two more strips of medicine to everyone:

"What everyone has in their hands right now is a strip of moxifloxacin and a strip of azithromycin. Why bring out these two relatively narrow-spectrum antibiotics when we already have broad-spectrum antibiotics like cephalosporins? It's because these two drugs have irreplaceable functions."

For example, azithromycin has a different antibacterial spectrum than cephalosporins and penicillin. For instance, cephalosporins and penicillin cannot cover mycoplasma and chlamydia.
To give a simple example, a patient has pneumonia, but not all pneumonia pathogens are effective against cephalosporins. For example, viral pneumonia, mycoplasma pneumonia, etc., will not respond well to cephalosporins.

Therefore, we should use azithromycin at this time to treat the symptoms, and the recovery will be faster.

This is also one of the research topics of Professor Chai and his team. It's not that any disease can be killed with cephalosporins or penicillin. That's not how it works.

The most scientific and effective clinical treatment is to choose an antibiotic based on the specific pathogen you are infected with.

As for those who have obtained the Moxisha Star, its effects are even more powerful.

In a sense, moxifloxacin, like cephalosporins, is a broad-spectrum antibiotic, seemingly capable of treating any disease and killing any bacteria. However, there are still significant differences between the two.

Cephalosporin antibiotics have good antibacterial effects against both Gram-positive and Gram-negative bacteria.

Moxifloxacin is a broad-spectrum antibiotic that has antibacterial activity against some atypical pathogens, such as mycoplasma, chlamydia, and Legionella.

It also has good antibacterial activity against anaerobic bacteria, so moxifloxacin is more effective against urinary tract infections, intestinal infections, and so on.

In addition, moxifloxacin can also be used in our original field of anti-tuberculosis treatment, especially for refractory and intractable pulmonary tuberculosis.

"Dean Jia, our current cure rate for anti-tuberculosis treatment is around 94%. If we add our traditional Chinese medicine and moxifloxacin, that cure rate can be increased by at least another 3 percentage points."

Jia Xuezhen replied with a smile:

"Dean Lin has provided us with bullets to shoot at the tuberculosis bacteria, so our clinicians have enough information to kill the enemy and become the hospital with the highest tuberculosis cure rate in the world."

Lin Sanqi nodded and reminded him:

“Tuberculosis treatment has already been carried out abroad, and the 94% cure rate can solve the problem for almost the vast majority of patients. Therefore, our Baoan International Hospital should differentiate itself from other hospitals.”

For example, if other hospitals can't handle refractory or intractable tuberculosis, but we can, then we won't lack patient resources. If all the world's refractory tuberculosis patients come here, we'll make a fortune.

Moreover, this group of difficult-to-treat tuberculosis patients are often those who have too much money and resources, leading to drug resistance due to misuse of medication, or those who have developed multiple diseases due to promiscuous lifestyles. These people are not short of money; we'll take advantage of them.

Hehehe~~~~
Everyone in the conference room chuckled softly.

Lin Sanqi positioned Bao'an International Hospital as a profit-making hospital that only accepts foreign patients and patients from Hong Kong and Macao, and operates entirely on a market-oriented basis, so it would definitely earn more foreign exchange.

Bao'an County People's Hospital, headed by Shen Qiushui, primarily treats patients from inland areas and adopts a low-cost, welfare-oriented hospital model.

Shen Guoming then spoke up:

"What about the price of these three antibiotics? If we want to produce them on a large scale, we have to consider the cost. If they are too expensive, the people in China still can't afford them."

Lin Sanqi blushed slightly because he had spent a long time talking to Wang Muye, the boss of Kenfu Pharmaceuticals, about how medicines are worth the price.

When it came time to make the purchase, he opted for the cheapest raw materials, choosing two million per ton.

If he hadn't emphasized that it was being exported to Africa, the straightforward Shandong man would have thought he, a southerner, was hypocritical, saying one thing to your face and another behind your back.

"I have already acquired 20 tons of raw materials, which is enough for now, and the cost is also within my budget."

But since several professors are here, I have something to say to everyone… (End of Chapter)