I am Emperor Wanli

Chapter 347: The two of us will be remembered forever along with the prince!

Soon Li Shizhen and Wan Quan were invited into the Qinzheng Hall.

After the greeting, Zhu Yijun asked them to sit down.

"We invited Mr. Dongbi and Mr. Mizhai here today for three main things."

Zhu Yijun still likes to get straight to the point.

Li Shizhen and Wan Quan listened quietly.

"According to the latest war reports, one of the biggest casualties in this southern expedition is malaria. So far, 2,727 soldiers have been infected with malaria, 1,165 of whom have died, and 1,285 are still lying in the military hospital.

It can be said that malaria is the biggest obstacle for the Ming Dynasty to conquer the South China Sea and continue to expand its territory. "

At this point, Zhu Yijun turned to look at Li Shizhen, "I have asked you to make a secret medicine to cure malaria. How is the progress?"

Wan Quan was very curious and turned to look at his good friend Li Shizhen.

Medicine for malaria?
This thing has been one of the most vicious miasma since ancient times and there is no cure.

Li Dongbi, have you found some secret recipe to cure malaria?

You didn't even tell me!
Are you still my good brother?
Li Shizhen sensed the complaint in Wanquan's eyes, turned around and smiled, and answered Zhu Yijun's question: "To answer your Highness, after I got your secret recipe last time."

Having said this, Li Shizhen stopped in time and looked at Zhu Yijun with expectant eyes.

Your Highness, can you tell me what's next?
Zhu Yijun gestured, "Mr. Mi Zhai is not an outsider. He will also share his secret recipe for prevention later. You can share what you have and learn from each other."

Li Shizhen said confidently: "I sent people to search for Artemisia annua and Artemisia affine everywhere, register them according to the local area, crush them and make juice, then blend them with strong liquor, filter them carefully, dry the mixture of strong liquor and juice into powder in the shade, mix them with honey and other things, seal them with wax into shells, and send them to Lingnan and other places for patients with malaria to take.

After two years of screening, we found that the best results were found in six counties in Yunnan, including Qujing, Wuding, and Chuxiong, two counties in Shandong, Tai'an, and seven counties in Huguang, including Changsha, Chenzhou, Hengzhou, and Shizhouwei. "

Li Shizhen thought about the data in his mind, "The cure rate of Yunnan's secret artemisia annua is 6.8%, Shandong's secret medicine is 7.1%, and Huguang's secret medicine is 7.8%.

If the drugs are used in combination, for example, taking the Yunnan secret medicine first and then the Shandong secret medicine, the cure rate is 8.2%. If the secret medicines from all three places are taken in sequence, the cure rate is 8.5%.

Wan Quan certainly knew the meaning of the new word cure rate. He stared at Li Shizhen blankly and asked absentmindedly, "Dongbi, so there is a cure for malaria?"

"There are medicines that can cure it, but they are not perfect. The highest rate is only 8.5%, not 90%."

If they weren't in Qinzheng Hall, Wan Quan would really want to roll up his sleeves, step forward and beat his friend up!
Malaria! A terminal illness! You thought it was just a cold and a stomachache?
There is medicine to treat it, and the cure rate is as high as 80%. What else do you want?
I still want 90%!

Li Dongbi, your heart is floating!
Zhu Yijun spoke up: "Li Shizhen!"

Li Shizhen trembled, stood up immediately, and then knelt down again.

"Immediately prepare more materials, work day and night to make them, and send them to the South China Sea front as soon as possible to relieve the suffering of the soldiers.

This secret medicine for curing malaria must be kept secret in the Ming Dynasty! The ingredients, preparation method, treatment process and data must be kept strictly confidential and no information can be leaked. Anyone who violates this order will be executed!"

The secret medicine for curing malaria!
Good things that money can't buy.

One of the most important treasures of the Age of Exploration.

Malaria is one of the most powerful killers in the Age of Discovery. Many sailors, braving the raging waves, have died from the bites of a few tiny mosquitoes.

It was not until the discovery of cinchona bark that humans began to have a real cure for malaria, and the Age of Exploration entered its golden age.

The cinchona tree is grown in South America, which is out of reach for the Ming Dynasty, so it is better to use artemisinin directly.

When the deeds of Tu Aoao were previously publicized, senior civil servant Zhu Yijun had read the relevant information.

One of the difficulties with artemisinin is that it is not Artemisia annua, but Artemisia affine. In Li Shizhen's Compendium of Materia Medica, these two plants were only mentioned briefly without any subdivision, which makes it easy to confuse them. Another point is that even if they are both Artemisia affine, the effects of Artemisia affine produced in different places are completely different, which is full of metaphysics. In addition, artemisinin is insoluble in water, but soluble in ethanol, that is, alcohol.

It is not heat-resistant and will decompose when slightly heated. If you boil the medicine and drink it according to the old method, you will only drink a little more cellulose and chlorophyll in the end, and it will not have any therapeutic effect.

He summoned Li Shizhen to Beijing, and in addition to supporting him to continue compiling and improving the "Compendium of Materia Medica", he also gave him several "scientific research projects", artemisinin being one of them.

Now Daming has finally developed it, and it’s effective.

Nowadays, any drug with a cure rate over 50% is considered a miracle drug.

With this thing, Ming Dynasty has the first-mover advantage. You will be in danger of death if you enter the tropical areas where malaria is rampant, but we will be fine and we don’t need to fight a war. This place belongs to Ming Dynasty.

It must be kept strictly confidential.

It's like the secret bitter tea of ​​the Ming Dynasty Navy, which uses extremely bitter tea and mixes it with crushed lemon slices so that you can taste only the bitterness but no sourness. It's even better if you add sugar and salt.

One of the main features is confidentiality, not letting you know what the ingredients are.

Anyway, the Ming navy won't get scurvy during their voyage after drinking this secret bitter tea. Doesn't that mean they are far ahead again?

After giving the solemn instructions, Zhu Yijun helped Li Shizhen up and turned to Wan Quan.

"Mr. Mi Zhai, I entrusted you with the secret method of smallpox. Is it perfect now?"

This time it was Li Shizhen's turn to be stunned.

I only have malaria, and you want to go straight to treat smallpox?

Wan Mi Zhai, you are even more powerful than me! Then why were you glaring and puffing your beard just now?
Wanquan stroked his beard proudly, his eyes narrowed into slits with a smile: "Your Highness the Crown Prince gave me a secret method before, saying that smallpox cannot be cured, but it can be prevented. I deeply agree with it.

According to ancient records, Sun Simiao, the King of Medicine in the Former Tang Dynasty, used the venom from the mouths of smallpox patients to smear on people's arms to prevent smallpox infection. It is said that this method was somewhat effective. In some places in our dynasty, there are doctors who follow this method and use the venom from patients to smear on people's bodies to prevent smallpox infection.

But life and death are determined by fate, and deaths are everywhere. It should not be used unless it is absolutely necessary.

The prince taught me a secret method and asked me to collect cowpox from cows, usually from the ulcerated part of the female cow's breast. After collecting the cowpox venom, I found a death row prisoner to test it. I first pierced the prisoner's arm and injected the cowpox venom into the wound.

The prisoner had a slight fever for six to ten days, and the wound scarred and recovered. Then the skin was pierced again and the poisonous juice of a smallpox patient was injected into the wound, and the prisoner was safe and sound.

After testing 259 death row prisoners, the results were the same, none of them were infected, this method was very good. Later, I was ordered to offer rewards to children in Jingji, Shandong, Shanxi and other places where smallpox was prevalent, and a total of 14,675 people were vaccinated with cowpox.

The epidemic was raging, and all the unvaccinated children around got smallpox, but none of the children who were vaccinated against cowpox got smallpox! "

Wan Quan knelt on the ground excitedly, clasped his hands and said loudly: "Your Highness, this is a divine prescription bestowed by heaven! The people of the world have suffered from smallpox for a long time since ancient times! Now the prince has bestowed the immortal method, and the people are fortunate!"

Li Shizhen knelt down and said loudly: "God bless the Ming Dynasty and grant His Royal Highness the immortal magic formula to save the people of the world from disaster.

I propose that the secret medicine for curing malaria be named the Crown Prince's Immortal Seed, and the method for preventing smallpox be named the Crown Prince's Divine Prescription! We should spread the word throughout the world, so that all the people of the Ming Dynasty can celebrate! The world is lucky to have His Royal Highness the Crown Prince! The people are lucky to have His Royal Highness the Crown Prince!"

There is a future!

Lao Li, you have a bright future!
Zhu Yijun said calmly: "You two can discuss this matter with the Taichang Temple."

Li Shizhen and Wan Quan were greatly relieved to see that Zhu Yijun readily accepted their suggestions and asked the Taichang Temple to take charge of the matter.

His Royal Highness the Crown Prince is famous throughout the ages, and if we follow him, won’t we also be famous for generations to come?

Malaria and smallpox!

Our reputation in future generations will be on par with Bian Que, Zhang Zhongjing, and Sun Simiao. It makes me excited just thinking about it!
It is necessary to let the Taichang Temple handle the publicity work, they are professionals!
Zhu Yijun helped the two men up and continued, "Gentlemen, I have a third matter to discuss with you."

Li Shizhen and Wan Quan immediately sat up straight, looking like they were ready to go through fire and water!
(End of this chapter)