Chinese medicine: When you do things to the extreme

Chapter 170 The feeling of 'Yanqing' is really great (please subscribe)

Surgery is scheduled based on the surgery day.

Today is Wednesday, and Tan Zhongyu's team does not need to schedule elective surgery.

Zhou Yanqing and several of his fellow students quickly went through all the patients in the group.

When leaving the last ward after the rounds, Zhou Yanqing warned: "Today's task of changing dressings and doctor's orders is heavy, and it may take more time than usual."

"But no matter what, we must do our best to get things done."

"You will also have a day when you become senior brothers, and you will need your junior brothers to help you in the future."

"Similarly, the brothers who are now passing on these tasks are also the ones who have done things for the brothers in the past. This is a positive inheritance."

"Don't have too many thoughts in your mind, okay?"

Upon hearing this, Wang Qingyao immediately said, "Brother, don't worry, we all understand these principles."

"See you this afternoon then."

The medical instructions and dressing changes for all patients in the group must fall on the shoulders of three people and cannot be dealt with arbitrarily.

Many flap transplant patients in the hand surgery department need to change dressings and disinfect every day after the pressure packs are removed, and many medical orders also require very careful cleaning.

It takes quite a while -

After finishing his rounds, Zhou Yanqing immediately went into the laboratory to carry out further detailed processing of the revived cells.

Zhou Yanqing's previous "new pathway" for osteosarcoma cells had only been achieved at the molecular and mRNA levels. After mRNA, there are also miRNA and lncRNA that regulate mRNA, which all need Zhou Yanqing to try one by one.

If we try to understand this pathway, the molecular level, that is, the protein that is finally expressed, is the final manifestation and can directly act on the cell.

However, the amount of protein secretion needs to be regulated by mRNA, either promoting or inhibiting it.

If the mRNA content increases or is amplified, the corresponding amount of protein synthesis will decrease or increase.

Similarly, mRNA is also regulated by miRNA, and miRNA indirectly affects the protein content by regulating the amount of mRNA, and more indirectly affects many cellular behaviors of tumor cells, such as growth, reproduction, and migration.

Zhou Yanqing also doesn’t know whether the pathway he created is useful, or whether it can eventually produce targeted drugs for treating tumors.

But Zhou Yanqing has to do it because the only most effective drug for treating cancer currently is targeted drug.

If you don't master the research process through trial and repetition, even if one day you find the most effective target pathway, you may miss the correct answer.

You may fail a hundred times before you succeed, but without a hundred failures, there will generally not be the initial success.

Even the most talented person needs to accumulate basic skills.

Over the past month, Zhou Yanqing has been reading, reading theories and literature like crazy, hoping to find the miRNA upstream regulatory element that has the strongest connection with the current mRNA from the numerous documents.
Now Zhou Yanqing of course has to refer to other people's experiments. If Zhou Yanqing can discover and name a new mRNA and miRNA on his own, then Zhou Yanqing's level in the field of basic scientific research will truly reach the peak.

A tall building starts from the ground. Many mRNAs and miRNAs were discovered and named in foreign laboratories, and their existence does play a role in the regulation of tumors.

However, decades of research and development have not found the most suitable and effective pathway to make the treatment of certain tumor cells particularly effective.

……

Once the experiment begins, it is unlikely to stop easily.

However, because Zhou Yanqing was in charge of the task of acting as the chief resident, he did not dare to arrange his experimental tasks too full.

At least he had to ensure that, even if he had to abandon the laboratory workbench immediately for an emergency consultation, the loss would not be too great.

But fortunately, the process went smoothly.

Zhou Yanqing chose the transient transfection technology. After the operation is completed, incubate the cells in the cell box for twenty-four hours before proceeding with other operations.

This time, Zhou Yanqing chose transient transfection of miRNA.

After completing this step, Zhou Yanqing will next perform gene knockout of miRNA and then compare the cellular behaviors of the two.

After finishing the operation, Zhou Yanqing tidied up his white coat and took off his gloves, and murmured in a low voice: "It would be great if we could get a batch of stable cell lines, but this requires stable transfection and plasmid embedding technology."

"This is too much trouble. I'm just doing a preliminary experiment for the next project, so it doesn't need to cost so much."

“However, some larger laboratories have many cell lines of their own. Unfortunately, my pathway is not commonly used in our laboratory.”

The size of a laboratory is reflected to a certain extent in many factors such as their experimental equipment and cell line storage.

There is a saying that goes, how can one generation of hard study be compared to three generations of others in business?

The same is true for laboratories. A lot of wealth needs to be accumulated step by step. No matter how strong you are or how talented you are, it takes time to accumulate more than others.

It’s not that there are not enough cell lines in Professor Tan Zhongyu’s laboratory, but that there is no new pathway chosen by Zhou Yanqing.

If Zhou Yanqing obtains a stable cell line, it would be considered a treasure left for the laboratory.

"Fortunately, I now have relatively sufficient free funds." Zhou Yanqing walked out of the laboratory.

The time had only come to eleven twenty.

"What are you having for lunch?" Zhou Yanqing asked the four-person group that Sina had just joined.

Wang Qingyao replied very sensibly: "Brother Zhou, would you like some rice?"

Gaimafan is rice with gravy and it is called differently in different places. The most popular name in Shashi is Gaimafan.

Wang Qingyao no longer calls Zhou Yan Brother Qingqing, because he also has the word "Qing" in his name. It seems that the fellow disciples of this session are dominated by the word "Qing".

The attending physicians are Liu Qingshan, Dr. Liu Wanqing, Dr. Zhou Yanqing, and Master Wang Qingyao.

"Then let's have the rice, everyone has no objection, right?" Zhou Yanqing was too lazy to say more. After replying, he quickly ordered four servings of De Tianshun.

Then I looked at the final price, damn, it was only one hundred and twenty.

This is enough to go out for a meal at a cheaper restaurant.

But Zhou Yanqing still chose to pay quickly and started to sort out the messages sent by other brothers again.

The first thing Zhou Yanqing looked at was Brother Ning Zhu’s chat box.

Ning Zhu's words are full of drama -

Around 8:40: "Yanqing, I'm already at the competition venue. The weather is pretty good today. I'm also in very good shape."

“It feels good to have a steady and steady pace.”

Even through the screen and several hours later, Zhou Yanqing could still feel Ning Zhu's confidence at that time.

The feeling of crushing others is naturally good, and it’s good enough that Ning Zhu’s self-confidence didn’t overflow.

9:20: “I just greeted Fan Yunsong from the Second Hospital, but he ignored me.”

"Does this mean you look down on me?"

Zhou Yanqing was stunned when he saw it.

But soon, at 9:25, Ning Zhu sent a message: "It turns out that Brother Song wore headphones..."

The names have changed, one is Fan Yunsong and the other is Brother Song.

"Song Ge is very capable. He is 34 years old this year and has a good chance of winning the championship in our track."

"If my strength is still about the same as last year, I might really be defeated by Brother Song."

"Last year I barely won the second prize, but Brother Song won the first prize and ranked second. If it weren't for another brother who has been promoted to associate professor, Brother Song would have been first."

"If Brother Song still ranks second this time, then he will be named Fan Lao Er, which sounds refreshing."

No, Brother Ning Zhu, why are you so dramatic? I don't usually see you being so dramatic. Could it be that because of Ren, the chief resident, Brother Ning Zhu suppressed his temper?
Ten thirty.

"I'm about to enter the arena. The first round will be the basic skills of incision. Brother Song is in the second round and he made a great start."

"This basic skill is really strong. The final score is as high as 93 points. I estimate that I can only get about points."

“It’s still hard to make up for a gap of a few years.”

"But don't worry, in the final evaluation, suturing will account for a higher proportion of the final score!"

"And it can also exceed the full score, just like when you, Yanqing, enrolled as a doctoral student."

"The basic suturing skills competition will be held tomorrow morning, and the specialized skills competition will be held on Saturday morning."

Ten fifty-seven.

Ning Zhu: "My score for incision surgery was 86 points, which is a little higher than I expected."

After reading it, Zhou Yanqing replied: "Brother Zhu, keep going, you will have your home advantage soon."

"Not in a hurry."

Ning Zhu should be holding a cell phone at this moment——

"I'm not in a hurry."

"The second-ranked brother Tian Minyin only scored 89 points, which is not that far behind me."

"Oh, this Tian Minyin is the attending physician in Professor Deng Peng's group. He is three years older than me and is thirty-three this year."

Zhou Yanqing has a general understanding of the Hand Surgery Department of the Second Hospital, which also has three groups.

Professor Tang Chengqian, Professor He Yuanzhen, and Professor Deng Peng.

"Thank you, Brother Zhu. I'll introduce you to me next time." Zhou Yanqing knew very well that anyone who could be remembered by Brother Ning Zhu must not be an ordinary person.

They should be a group of particularly outstanding people in the Second Hospital.

Immediately afterwards, Zhou Yanqing went to sort out the information sent by Senior Brother Yu Yue.

Yu Yue’s message is similar to that of Brother Ning Zhu, but not as outlandish as Ning Zhu’s.

Ning Zhu mainly gave Zhou Yanqing some basic knowledge about several ruthless doctors in the Second Hospital.

Professor He Yuanzhen's student Lu Xin and Professor Tang Chengqian's student Lin Meng both achieved good results in the first quarter of the competition.

The final score of the incision was as high as around seventy-five points.

To be more specific, the top three should be Yu Yue with 76 points, Lu Xin with 75.5 points, and Lin Meng with 74 points.

There is a three-year age gap between Yu Yue and Ning Zhu. It is impossible for Ning Zhu to have made no progress in these three years, and it is also impossible for Yu Yue to surpass Ning Zhu over so many years with the same qualifications.

Unless Yu Yue also used cheats like Zhou Yanqing, or his talent was far superior to Ning Zhu's.

A high score of seventy-six points is actually very, very good.

"Congratulations, Brother Yu, you got first place in the first quarter. You just need to keep steady from now on." Zhou Yanqing's reply to Yu Yue was different from Ning Zhu's.

Yu Yue's chat page immediately showed that the other party was typing...

Ten seconds later, Yu Yue typed back: "Yanqing, you feel really good."

Zhou Yanqing's pupils shrank when he saw this: "???"

What the hell is this vicious word?
Yu Yue immediately replied: "Yanqing, I'm not driving now. What I mean is that the feeling of accumulating strength and then releasing it is really good that you usually live in."

"In fact, I feel that my incision skills have not yet fully demonstrated their true strength. If I perform beyond my normal level, I might be able to get 79 points."

"But it doesn't matter. I have accumulated a lot of experience and I am calm and not worried."

"I now understand that this is how you felt when you were taking the doctoral exam."

After possessing absolute strength, Yu Yue discovered that what he had expected before was just a matter of going through the process, and everything happened naturally.

Now, if he wants to win the championship or the special prize, he doesn’t have to compete for it, but just go and get it. As long as he performs steadily, there will be basically no problem.

"But Lu Xin is also very good. It can be seen that he still has some strength left and did not give his all in the first round."

"The Medical Skills Competition is not a competition. There is no such thing as strategy. Everyone just gives 90% of their abilities at the first opportunity."

"A glimpse of the whole picture shows that I think I am a little bit more stable."

"Master is here." Yu Yue replied.

"Brother, you continue chatting with the master. I'm going back to take my fellow disciples to dinner." Zhou Yanqing ended the chat with Yu Yue.

Immediately afterwards, Zhou Yanqing also very carefully replied to the messages from Senior Brother Liu Wanqing and Tian Chao.

The two of them basically talked about Yu Yue as the main topic.

Liu Wanqing's incision score ranked fifth, with only 73 points.

Tian Chao ranked tenth with only 70.5 points.

Tian Chao's result is quite impressive. If he works hard for a few more years, he may win the special prize like Yu Yue.

You have to know that Tian Chao is only in his third year of master's degree.

Of course, if Tian Chao is compared with Zhou Yanqing last year, he is still far behind.

As he replied and looked at his fellow students' scores, Zhou Yanqing became calmer.

There are some truths that all the fellow disciples understand, and Zhou Yanqing certainly understands them too.

Lift weights lightly.

When your strength has reached a certain level, there is no need for others to acknowledge your awesomeness in person.

It is impossible for others to take away his own strength. Now, in terms of technology alone, regardless of the thickness of theory, Zhou Yanqing will not be afraid even if it is Associate Professor Huang Xianming or other associate professors.

Even if we lose, we will lose gracefully and will never be crushed.

Of course, if it comes to high-end techniques, then an ordinary associate professor might have to stand next to Zhou Yanqing as punishment.

There is no other way except to stare blankly.

This is Zhou Yanqing today.

It feels so good to make light of a heavy task.

When Zhou Yanqing appeared in the department, Wang Qingyao and others looked quite cautious. They hesitated while putting away their cell phones, fearing that Zhou Yanqing would see the excitement on the field.

Zhou Yanqing was very displeased with this shy look, and rolled his eyes and said, "Don't hide it, I knew about the competition earlier than you did, and I know it in more detail."

"Just talk about whatever you want."

Finally, Chu Weiming couldn't hold back and said excitedly, "Brother, we may win the special prize in both tracks this year."

"Yeah? So?"

"What's the big deal? Isn't this expected?" Zhou Yanqing put his hands behind his back.

"..."

(End of this chapter)