blood feud

798: Penicillin

What Bai Shujie wanted to impress Payne was the "penicillin", penicillin g, which was cultivated three years ago, extracted in small batches a year ago, and only entered clinical trials in Pyongyang.

It is not difficult to cultivate penicillin and concentrate penicillin. What is difficult is the production of nutrient base, control of ambient temperature, batch cultivation, extraction, purification, drying and preservation.

At that time in Chengde, there was no industrial capacity to produce compressors, and there was no chemical factory to produce foaming agents, so there was no way to produce air conditioners, and naturally there was no way to control the constant temperature state.

But, the production seed of cocciform bacterium, is to be through mixing o.5%,,, 1.0% corn steep liquor by frozen tube spore, then implants triangular flask to cultivate original rice-loving spore, then moves into special-made culture bottle to produce rice spore in batches (also known as Production rice), pro-rice and production rice were all statically cultured at 25°.

There is no difficulty in the production process, but the difficulties faced by Bai Shujie are mainly related to equipment and instruments.

The first is the biological microscope, and it needs a complete set of color filters. After occupying Chengde, two microscopes were found in several hospitals, but they were not practical.

Later, when Bai Shujie's soldiers were trapped in Shentouling and their lives were hanging by a thread, Zhao Jinxi, in a panic, ordered Yang Erya's ranger to launch the first devastating strike against the little devils in the Pingjin area.

That battle wiped out all the little devils in the Tianjin Japanese Concession, regardless of gender, age or age. As for the big hospitals of the little devils, they were looted, and all kinds of medicines and medical equipment were piled up like mountains after they were shipped back to Chengde.

Bai Shujie narrowly escaped death and was rescued back to Chengde. In the items Yang Erya snatched back, he found two microscopes made in Germany and one microscope made in Sweden.

After comparison, the microscope produced in Sweden was confiscated by Bai Shujie, and the two microscopes produced in Germany are now used in field hospitals.

With a high-quality standard microscope, you can observe various changes such as the formation, growth, and enrichment of filamentous bacteria and cocciform bacteria at any time, and you have the conditions to record a set of the most complete data from scratch, so as to create a standard The process finally triggered Bai Shujie's idea of ​​producing penicillin.

The first equipment Bai Shujie needs is a set of distillation facilities capable of producing injection water.

The penicillin produced by the "freeze-drying method" is all white powdery particles. Penicillin cannot be dissolved in glucose solution. When it is to be injected intramuscularly or intravenously, the penicillin must first be dissolved in water.

In Chengde, there was no condition for preservation, and each time we could only make a little temporarily, to ensure that officers above the battalion commander in Rehe could use a penicillin of 5000 units after being injured.

The second set of equipment that Bai Shujie needs is a high-power air conditioner that can control the constant temperature state. This matter has always troubled him.

In a recent war, a good thing fell from the sky, the latest production of the world's first high-speed train "Asia" by the little devil.

Because there is no railway, this luxury train Bai Shujie could only reluctantly part with it and "give it" to Chengde, but he did one thing, that is, dismantled the large air-conditioning equipment on the train.

After arriving in Pyongyang, why did Bai Shujie's first thing be to order Zhang Yushu, the "Mayor of Pyongyang", to quickly dig the cave with grain as wages, and the deeper the cave, the better.

It turns out that in order to obtain the best-quality and highest-yield cocciform bacteria, both parenting and production of oryzae spores must be stored in a refrigerator at 5°C.

Bai Shujie has neither a refrigerator nor a freezer. He can make a simple dehumidifier to ensure the humidity of an independent space.

Now there is a high-power refrigeration equipment, but to ensure a constant temperature, it is better to be in a cave, and at the same time it is convenient for confidentiality and security. Bai Shujie knows that once penicillin comes out, troubles will not be small in the future.

Because Bai Shujie drilled into the cave whenever he had time, Huang Qiaoyun, the head of the security team, said last time that he was not doing his job properly: the good command didn't stay there, but wanted to run into the cave, and no outsiders were allowed to follow.

The third problem for Bai Shujie to mass-produce penicillin is the problem of the packaging carrier. To put it bluntly, it is a small glass bottle that can be "fully sealed" and "easy to transport".

There is no glass factory or rubber factory in Chengde. Even if we find a few replacement glass bottles, we still can’t produce non-toxic rubber stoppers. I once thought about using wax pellets to seal them, but the effect is not good.

After robbing Jinzhou, Yingkou and Lushun, Bai Shujie obtained an alcohol factory, a soda ash factory, a nitric acid factory, a sulfuric acid factory, a rubber factory, a glass factory, a cotton yarn factory, and most importantly, a small steelmaking factory.

With these factory equipment, Bai Shujie doesn't need to mass-produce anything for the market. The first thing he needs to do is to finally mature the conditions for his own "pH calibration".

The culture of penicillin must be carried out under weak acid conditions. What is a standard weak acid environment is to calibrate the "pH". The easiest way is to make a ph test paper.

The strains are all ready-made, and now we have the basic conditions, so after arriving in Pyongyang, it is "everything is ready, and the east wind blows again,"

Wan Haotian's "special medical team", with Bai Shujie chasing after his butt every day, finally added more than 320 young students and began to operate at full capacity.

It is precisely because of the need to ensure a relatively stable environment that Bai Shujie sent a regiment to "shamelessly provoke" Kawagishi Fumisaburo's No. 20 Division, and issued an unprecedented order "no unlimited expansion of the scale of battle".

If Bai Shujie hadn't killed little devils in the past, like cutting winter melons, which caused him to "betray the country and no one would dare to buy it", the commanders and fighters of the whole army would probably suspect that Bai Shujie had "corrupted" and was about to become someone like Jiang.

In the blink of an eye, it has been a month since the Feilong Expeditionary Force entered North Korea. The first process of penicillin has finally been completed, and the real penicillin, which can be used in large quantities for clinical trials, has been obtained. Equivalent to 1 of the original 240 units.

The book explains that in order to make his clinical trials convincing, the "Special Drug Laboratory" of the field hospital is divided into six areas, each housing more than 1000 wounded from the previous World War, as well as "little children" of different genders and ages. devils captive".

Bai Shujie brought Payne to this experimental site, which is the clinical experimental area where the age ranges from 5 years old to 60 years old. The diseases include patients with pulmonary tuberculosis (commonly known as tuberculosis) who can only wait to die, and patients with anthrax bacillus that cause deep skin ulcers. There is also a group of "syphilis" patients.

These three types are all "terminally ills" that cannot be cured in this era.

Even Wan Haotian, the top person in charge of the special medical team, is not sure whether he can cure these three kinds of patients, but with the deepening of the medical treatment process, the patient's condition is getting better and better.

Payne looked at the scene in front of him, and exclaimed immediately: "This is the gospel of the whole world, and it is the greatest miracle of mankind."

He is a business man with a keen sense of the market, and of course extraordinary responsiveness.

When he saw so many "seriously infectious" patients who were not infected, he asked to check the clinical records.

Wan Haotian strictly abides by the confidentiality regulations, so naturally he can't agree, but intentionally or unintentionally casts his eyes on Bai Shujie.

Bai Shujie had another purpose, and at the same time he knew in his heart that it was impossible to leak the secret just by looking at the medical records, so he secretly nodded in agreement.

Payne carefully read through almost all the medical records, and then checked the patients one by one. Two hours later, he asked in a deep voice: "Excuse me, Commander, can I take a batch of photos here, which will be useful for future marketing plans?" very critical,"

Sure enough, it is worthy of being an old fritter rolling in the international trade market.

Bai Shujie was secretly happy, but his face looked calm: "Mr. Payne, I think you should understand that my place is an absolutely confidential place, and you are the first outsider in the world to enter this core area,"

"However, because of the previous transaction process, I think you are a truly reliable friend, so I brought you here for a visit. Since this is the case, I have no secrets from you. Except for me and this Doctor Wan, you shoot whatever you want,"

Back at the headquarters, Payne couldn't wait: "Mr. Commander, I apologize for what I said earlier. The mysterious East not only has a long history of civilization, but also has world-leading technological inventions and industrial manufacturing innovations. I think , the benevolent Mr. Commander invented this special medicine, and he will not care about benefiting more people,"

Bai Shujie nodded slightly: "Mr. Payne, you have been here for many years. You should know that the Chinese nation is a peace-loving nation. Their ancestral training is to be kind to others. If it weren't for the damned Japanese dwarf who was mad, we would not have stood up to fight,"

Speaking of this, she beckoned to the outside world, Wang Xinlan came in with two information bags, and Bai Shujie then continued: "Let me introduce, this Ms. Wang is my special and plenipotentiary assistant in this project, and I invite Mr. Payne to come over." , mainly for this matter, because I need to register patents in America and Europe at the same time, "

"Mr. Payne, once the patent application is approved, you will be the general agent in the Americas in the future. If we cooperate for a long time, in order to reduce costs, we can invest and set up factories in your hometown when the conditions are right. Don't worry, except you I won't do business with anyone in America, except

Payne's eyes lit up when he heard this, because he had already discovered the broad market "Qianjing" for this special medicine.

Now is the time to build relationships, so Payne dropped Bai Shujie and began to get close to Wang Xinlan: "Mister King, I hope we can have a happy cooperation in the future,"

Wang Xinlan smiled gracefully: "Mr. Payne, as long as you can meet one condition, we can set off tomorrow, probably in time for Christmas in your hometown,"

Payne rubbed his hands and said, "Beautiful lady, please tell me what conditions I need to meet,"

"Mr. Payne, this specific drug was developed by our commander-in-chief in order to alleviate the pain of soldiers' injuries. Apart from being able to reduce inflammation urgently, its biggest role is actually to save the lives of soldiers on the battlefield,"

Speaking of this, Wang Xinlan's face suddenly became stern and stern, and she almost stuttered every word: "The Japanese militarists are invading my motherland, and they are our sworn enemies. My condition is: as long as the If there is a Japanese invader on my land, this medicine cannot be sold to Japan, not even a single one,”

After all, what happens next, let's see the next chapter to break it down,

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