Today is the last day of his honeymoon, and Gu Zheng is very unhappy because yesterday Dean Zhang Guohua personally came to ask Ye Zhen to give a lecture at the main hospital before leaving.

Ye Zhen initially wanted to decline, but Zhang Guohua's enthusiastic invitation left her with no choice but to agree. Gu Zheng was so angry that he didn't even see the old man off when he left.

The atmosphere in the large lecture hall of the military hospital was a bit off today.

Even before entering, one could feel a heavy, oppressive atmosphere. The classroom, which could hold three hundred people, was packed to capacity, with even small stools added to the aisles.

The first three rows were filled with either gray-haired medical luminaries or high-ranking military leaders. There were even a few blond, blue-eyed foreigners, speaking in broken Chinese in hushed tones to their translators.

Klaus, the German orthopedic surgeon whom Ye Zhen had once crushed on the operating table, was among them. He stood with his arms crossed, his eyes filled with a playful mix of curiosity and anticipation.

Gu Zheng parked the Jeep downstairs in front of the administration building and turned off the engine.

"Honey, this is quite a scene." Gu Zheng glanced at the commotion through the car window, tapping the steering wheel with his finger. "Those foreigners are here on special permission from the Ministry of Health for an exchange program, and I heard they're incredibly arrogant. What if anyone dares to give you a hard time..."

"That was an academic discussion." Ye Zhen unbuckled her seatbelt, straightened her collar, and her expression was as calm as still water. "In the face of truth, there are no nationalities, only right and wrong."

She turned her head to look at Gu Zheng: "Are you waiting for me outside?"

"No." Gu Zheng pulled out the car keys, pushed open the door and got out of the car. His crisp military uniform made him look as slender as a pine tree. "I'll stay in the back row to cover for you. If I speak too well and someone gets jealous and tries to throw rotten eggs, I'll be in charge of intercepting them from the air."

Ye Zhen's lips curled up slightly, but she quickly regained her cool demeanor.

The moment I stepped into the classroom, hundreds of eyes shot towards me.

There was scrutiny, there was doubt, but above all, there was curiosity.

What kind of eloquent words could such a young girl possibly utter?

Dean Zhang Guohua sat in the first row, a fine layer of sweat already forming on his forehead. He hadn't expected so many people to come. He had originally intended for Ye Zhen to speak to the younger generation at his hospital, but unexpectedly, all the old fogies had shown up. He wondered where that old fellow Wu Wenqing had gotten the news; dozens of people from Peking Union Medical College Hospital alone had come. Although Ye Zhen performed excellent surgeries, these were all leading figures in the theoretical field, and even the slightest misstep could lead to embarrassment.

Ye Zhen walked onto the podium.

There were no opening remarks, no polite greetings, and not even a self-introduction.

She picked up a piece of chalk, turned around, and drew a huge triangle on the enormous blackboard with a "swish, swish, swish" sound.

Then, she cut the triangle horizontally into five layers.

The classroom was so quiet you could hear a pin drop. Everyone was watching her every move.

At the very bottom of the pyramid, Ye Zhen wrote four large characters with heavy strokes:

Personal experience.

"hiss!"

A collective gasp rippled through the audience.

Which expert present didn't get to their current position through decades of "personal experience"?

Put their livelihood at the very bottom?

This is a provocation! A blatant provocation!

The face of an elderly, gray-haired head of internal medicine immediately darkened, and he let out a heavy snort.

Ye Zhen ignored her and continued writing on the chalk, listing: [Case Report], [Cohort Study], [Randomized Controlled Trial]...

Finally, at the very top of the pyramid, she wrote down a few words that were considered cryptic in that era.

[Systematic Review/Meta-Analysis]

After finishing writing, she put down the chalk, turned around, and faced the crowd below the stage, which had already erupted in excitement.

"Dear teachers, this is the core of what I'm going to talk about today—the evidence hierarchy pyramid of evidence-based medicine."

"Today, we won't talk about surgical techniques." Ye Zhen's voice, clear and firm, resonated throughout the room through the microphone. "We'll talk about what makes a doctor treat patients."

The moment the words were spoken, the audience erupted in chaos.

"What do you mean? Putting personal experience at the very bottom?"

"Who are they looking down on? Does that mean they're putting us at the bottom?"

"Arrogant! Utterly arrogant!"

Several elderly professors were so angry they were glaring and bristling. If it weren't for the presence of foreign guests, they probably would have already slammed their fists on the table and started cursing. Zhang Guohua's heart was pounding in his throat. He desperately tried to signal Ye Zhen with his eyes, implying that she should tone it down.

Ye Zhen ignored it.

She picked up the pointer and pointed it at the most fundamental level: "personal experience".

"The seniors here may feel offended," Ye Zhen said calmly, "but the fact is that, in the realm of evidence in modern medicine, personal experience is highly unreliable."

"Whoosh!"

The entire audience erupted in uproar.

"Nonsense!" An elderly professor with completely white hair, sitting in the second row, suddenly stood up.

He was Dr. Qian, a leading authority in gastroenterology, who practiced medicine for fifty years and had countless students.

"Comrade Ye, according to your theory, does that mean my fifty years of medical experience is less valuable than a few cold, hard statistical tables?" Old Qian was so angry his hands were trembling. "I've examined more stomachs than you've eaten rice! This is a betrayal of the medical tradition!"

Many people nodded in agreement, their eyes filled with hostility as they looked at Ye Zhen.

Ye Zhen watched the excited Mr. Qian quietly without interrupting until the venue quieted down a bit.

"Professor Qian, what is your preferred treatment plan for severe gastric ulcers?" Ye Zhen asked.

Professor Qian straightened his back: "Of course, it's subtotal gastrectomy! It's the current gold standard, and countless cases have proven its effectiveness!"

"Okay." Ye Zhen nodded. "What if I told you that, according to the latest large-scale clinical data, more than 60% of patients with gastric ulcers can be cured through combination drug treatment, without needing to undergo surgery at all?"

Old Qian was stunned: "This...this is impossible! Medication can only alleviate the symptoms; the relapse rate is extremely high!"

"That's your 'experience'," Ye Zhen pointed out mercilessly. "Because what you get are all severe cases that internal medicine can't cure, what you see as 'all' is actually just 'survivor bias'."

She turned and pointed to the top of the pyramid.

"In the past, we relied on experience and intuition to treat patients, which was like blindly guessing without any knowledge. If we were lucky, we would guess correctly; if we were unlucky, the patient would pay the price."

"Now, we need to rely on data, statistics, and large-sample comparisons. This is evidence-based medicine."

Ye Zhen's gaze swept across the entire room, her voice not loud, yet deafening: "Simply put, it's an open-book exam."

Klaus, who had been leaning back in his chair, suddenly sat bolt upright. He took off his glasses, his deep blue eyes filled with shock.

Evidence-Based Medicine.

This concept is still in its infancy in the West, and hasn't even formed a complete system yet. How could this young female doctor in closed-off China possibly understand it?

"Nonsense!" Qian Xuesen remained unconvinced. "How can cold, hard data explain individual differences? Medicine is the study of humanity, not mathematics!"

Ye Zhen looked at Old Qian with a hint of respect in her eyes, but her tone remained firm.

"Professor, your experience is a treasure trove that has inspired countless articles."

The whole place fell silent.

"But it is not an article in itself." Ye Zhen walked slowly to the front of the stage, placed her hands on the lectern, and leaned forward. "The contents of the treasure trove are mixed; there is gold, and there is also sand."

"We need a way to bring together the 'treasury' of knowledge from countless experts like you, and then sift it through with a scientific sieve. We need to sift out the sand and extract the real 'gold bars'."

"This gold bar can be replicated, verified, and passed on to the next generation of doctors. This is the greatest respect for medicine."

Old Qian opened his mouth, wanting to refute, but found that his throat felt like it was blocked with cotton, and he couldn't utter a single word.

Looking at the pyramid on the blackboard, he suddenly felt that what he had held onto for half his life seemed to be truly wavering at this moment.

Ye Zhen didn't give him much time to think.

She picked up the chalk again and wrote a line on the middle layer of the pyramid:

RCT (Randomized Controlled Double-Blind Trial).

"To refine this gold bar, we need the most precise ruler." Ye Zhen tapped the blackboard. "This is the key point we're going to talk about—randomization, double-blindness, and large-sample control."

Professor Wu Wenqing, who had been sitting silently in the front row, suddenly began to breathe rapidly.

As another towering figure in general surgery in China, he keenly sensed the astonishing energy hidden behind these words.

This is not a surgical procedure.

This is a revolution in the way we think!

If it's true... then the level of medical research in China will leapfrog by a whole era!

"Randomized Controlled Trial..." The foreign expert team over there was in an uproar, with several people huddled together discussing it intensely, occasionally exclaiming "Mein Gott!"

Klaus even pulled out his notebook and started frantically taking notes like a primary school student.

Ye Zhen stood on the stage, looking at the faces below who had just been full of disdain but were now craning their necks and eager for knowledge.

She knew that the seed had been planted.

"Xiao Ye!"

Professor Wu Wenqing suddenly stood up, his movement so abrupt that he knocked over the teacup in front of him. Water spilled all over the table, but he was completely unaware.

"Could you... explain this 'double-blind' research in more detail?"

In the corner of the last row of the classroom.

Sitting in the back row, Gu Zheng watched the woman speaking eloquently on the stage, a slight smile curving his lips beneath his hat. This woman, usually as aloof as ice in his presence, was as fiery as a flame in this setting.

That's awesome!

He was even a little jealous of these old men who could openly listen to her lectures.

Ye Zhen did not answer immediately. Her gaze passed through the layers of people and landed on the last row of the lecture hall.

The light was dim there, and Gu Zheng sat leaning against the shadows in the corner. He pulled his hat brim down, obscuring most of his face, revealing only a section of his strong jawline. His military uniform made him stand out even in a crowd.

Their eyes met briefly in the air, separated by several dozen meters.

Gu Zheng didn't move, but simply placed his hands, clad in black leather gloves, on the table and tapped them lightly twice with his index fingers. It was a silent signal: go ahead and do it, he'll be there to support you no matter what.

Ye Zhen withdrew her gaze, and the last bit of tension in her heart caused by facing authority vanished.

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