"Dr. Yamada, you're finally here." The doctor from the imaging department looked at Dr. Yamada, with a slight smile on his lips, and he naturally knew that Aine's operation was successful.
Dr. Yamada looked around, swallowed, and said, "The third gene editing operation was a great success."
The sound was not loud, but it was loud enough for all the doctors in the conference room to hear clearly.
Except for the doctors from the imaging and neurology departments, everyone else was stunned. After a long moment, someone finally spoke up: "Is this true?"
Dr. Yamada placed the report on the table. "This is the result of our joint testing by the Department of Neurology and the Department of Imaging. The neuron survival rate has significantly improved compared to before."
After receiving the report, the doctor's eyes widened. The facts written in black and white appeared before him. He had to believe it: "Really... So, this means that we have defeated ALS to a certain extent?"
Dr. Yamada shook his head. "It's too early to declare victory. Now we have to prepare for the next operation."
"Neural reconstruction?"
"Yes." Dr. Yamada nodded.
"It's incredible that such a result could be achieved when the gene editing skills are not very advanced."
"Yes, and during these three operations, there wasn't a single cytokine storm. That little girl is really lucky."
Listening to the doctors' lively discussion, Dr. Yamada sighed and interrupted them: "Okay, everyone, although our technology is not very mature, we have achieved some success in gene editing. However, there is still a long way to go to completely cure ALS."
At this point, Dr. Yamada glanced at the other doctors and continued, "We've only slowed down the progression of ALS, so we need to complete the nerve reconstruction as quickly as possible and not give ALS a chance to recover."
Hearing this, the other doctors nodded one after another. They knew this very well in their hearts.
"I've already told Chihaya that we'll be collecting skin fibroblasts this afternoon," Dr. Yamada said, his gaze fixed on all the neurologists. "Once the collection is complete, we'll be preparing and quality-controlling iPSCs."
Dr. Yamada is much more confident about this operation than the gene editing operation. One reason is that this operation has a lower probability of cytokine storm and less damage. The other reason is that their NCNP is well-known for iPSC technology.
Their department can shorten the differentiation cycle of normal skin fibroblasts from six weeks to four weeks, and purify motor neurons through flow cytometry sorting of HB9+ cells, which is a capability that most countries do not have.
"Then Yamada, do we still need to perform optogenetic neuromodulation?"
Hearing this, Dr. Yamada was stunned, but then shook his head in denial. "That's not necessary. The current clearance and recovery methods are sufficient for a single-cause ALS like Chihaya's. Adding optogenetic neuromodulation will only burden her body."
"Well."
After finishing her meal, Aine was already waiting in the ward according to Dr. Yamada's instructions. When she arrived, a sterile operating table had been prepared in the ward. Of course, Dr. Yamada had already mentioned to her that this was a sterile operating table, so she naturally wouldn't be stupid enough to touch it.
Soon, the door of the ward was pushed open and the surgeon walked in. After the nurse prepared the anesthetic drugs and surgical instruments and confirmed that the sterile operating table had not been touched, he finally began the operation.
"Relax, we're just collecting some skin fibroblasts from the inside of your upper arm. It's not dangerous," the surgeon comforted.
"Yeah, I know. Doctor Yamada told me." Aine smiled slightly.
"Yeah, that's good."
After completing local anesthesia, the surgeon finally started this minor operation.
Chapter 373 New Equipment
Just as Dr. Yamada said, it was just a minor operation, and only about half an hour passed before the operation was over.
The surgeon saw that the bleeding had stopped and said to Aine, "The wound is fine now. You can be discharged anytime."
After saying this, the surgeon left the ward, followed by the nurse who had already cleaned up.
Seeing the surgeon leave, the girls who were waiting at the door also went in.
Xiangzi spoke first: "Xiao Ai, how do you feel?"
At this moment, Aine had already gotten out of bed. She nodded, "Not bad."
Aine moved her arm gently. Apart from the fact that the sensation had not yet fully recovered, she didn't feel much pain.
"Then...Aine-chan, when do you plan to be discharged from the hospital?" Su Shi asked.
Aine thought for a moment and gave an answer: "Emmm... I'll leave once my arms are fully feeling again."
As soon as she finished speaking, Xiangzi's body tensed up and the cell phone in her pocket suddenly vibrated. She took out her cell phone and saw that it was a call from her grandfather.
"Xiao Ai, I'm going out to answer a phone call."
"Ah."
Xiangzi pushed the door open and walked out. She stood in the corridor and answered her grandfather's call.
"Hey, Grandpa, what's up?"
Toyokawa Sadaharu's voice was calm as he told Xiangzi, "The American equipment you asked me to help you get has now been brought back."
"Eh?" Xiangzi's eyes lit up, and she asked excitedly, "Really, Grandfather? Where is the equipment now?"
"I'm at home now," Toyokawa Sadaharu replied. "Should we ship it to NCNP for you now?"
"May I?"
"I'll let the butler go."
After hanging up the phone, Toyokawa Sadaharu handed the matter over to the housekeeper and sat alone on a wooden chair.
Xiangzi's voice was excited. Did she think these devices would be able to save the little girl? Now... she seemed to have just undergone her third gene editing surgery, and she didn't know the result... But judging by Xiangzi's tone, it shouldn't be bad, right?
Although he didn't want Xiangzi to fall in love with a girl, he had no choice but to make some compromises because Xiangzi was the only heir of the family and was extremely talented.
At the same time, after putting the phone back into his pocket, Xiangzi immediately turned around and ran towards Dr. Yamada's diagnosis room. As long as he told Dr. Yamada about this, then the subsequent microenvironment regulation + Qi IIsan zero silk research chess 彡飡 surgery would not be so difficult, right?
Not long after, Xiangzi ran to the diagnosis room and knocked on the door gently, but no one answered.
Huh? Strange, why didn't Dr. Yamada respond? Hasn't he returned yet?
Just as Xiangzi was thinking, a nurse came to her and asked, "Are you looking for Doctor Yamada?"
"Yes," Xiangzi nodded gently, "I have equipment I want to give him."
"Equipment?" The nurse tilted her head, not quite understanding what Xiangzi meant. NCNP had no shortage of equipment, and she had never heard Dr. Yamada mention replacing equipment. "What equipment are you going to give Dr. Yamada?"
"It's for ALS."
"ALS?" After hearing this, the nurse's face became less confused. "Do you know that child, Aine?"
"Well, she's my girlfriend."
"Oh, then please sit aside and wait for a while. I'll contact Dr. Yamada."
"Thank you."
After sending a message to Mu and explaining what he was going to do, Xiangzi sat down quietly on the bench and waited for Dr. Yamada.
Soon, she heard hurried footsteps behind her. Xiangzi turned around and happened to meet the eyes of Dr. Yamada, who smiled and nodded at her.
Seeing Dr. Yamada, Xiangzi stood up from the bench and said, "Dr. Yamada, you are finally back."
"Yes." Dr. Yamada nodded. "Sorry to have kept you waiting, Ms. Toyokawa. What kind of equipment do you mean?"
After the nurse contacted him, he said goodbye to the doctor in the conference room and hurried to the diagnosis room. He didn't think Xiangzi was joking when she gave him the new equipment, nor did he doubt whether the equipment was defective, because the strength of the Toyokawa family was there, and there was basically no possibility of any problem.
If there really is better equipment, it would be feasible to reduce the probability of cytokine storms during microenvironment regulation surgery to a certain extent.
"As for the equipment, it's on its way here now," Xiangzi replied. "I asked my grandfather to get it from America."
"America..." Dr. Yamada nodded and breathed a sigh of relief. As long as the equipment was from a developed country or a mysterious oriental country, it was worth trusting. At least it was not something unknown.
After more than ten minutes, Xiangzi's phone rang again. It was the housekeeper: "Miss, the equipment has arrived. You and the doctor need to come down, otherwise the hospital staff will not let you in."
Hearing this, Dr. Yamada nodded and said, "I understand. I'll be down right away. Toyokawa-san, you just wait here."
"I understand." Xiangzi nodded.
……
When Dr. Yamada came up again, there was a dense layer of sweat on his forehead.
"Doctor Yamada, how is it?" After seeing Dr. Yamada, Xiangzi felt a little anxious. She was not sure whether the equipment she bought was compatible with the surgery performed by Dr. Yamada and his team.
Although Dr. Yamada was panting, a smile remained on his face. "I and other neurologists have already seen it. It's really good. It's the latest American device and can be fully applied to microenvironment regulation."
After a pause, Dr. Yamada continued, "However, the Toyokawa family is really amazing. They can actually get the latest model."
"Really..." Xiangzi was stunned. He never expected that his grandfather could get such a thing.
"Yes." Dr. Yamada nodded. "After that, I'll have the doctors in our department use this to prepare reagents for microenvironment regulation."
Although it is not certain how much the risk can be reduced, it is definitely better than what is currently available in hospitals. With more advanced equipment and the theories they have already tested, Dr. Yamada believes that the results will definitely be better than they are now.
"By the way, Dr. Yamada." Xiangzi opened his phone. "The bank card I gave you before, there's not much money left, right?"
Hearing this, Dr. Yamada was stunned. He nodded, because experiments are very expensive things. The bank card that Xiangzi gave him before had been used up for more than two-thirds.
"After that, I'll transfer some money to that card. You just need to conduct the experiment and help Xiao Ai with her treatment."
Dr. Yamada nodded. He knew all this very well, as Xiangzi had told him the same thing before.
Seeing that Xiangzi was still sleeping, Dr. Yamada said, "Well, everyone else has paid for Chihaya's medical expenses..."
"Is that so..." Xiangzi nodded. "Then... is the medical expenses enough now?"
Seeing Dr. Yamada nod, Xiangzi let out a long sigh.
Chapter 374 Hailing’s Invitation
The next day, at Aine's house.
"Damn it, I didn't hold it firmly." Aiyin looked at the phone that fell on the bed, her left hand shaking.
When she was discharged from the hospital yesterday, Dr. Yamada told her that if there was nothing else to do, she should try to exercise her muscles at home. Of course, she didn't need to do any strenuous activities, as she couldn't do any. She just needed to do some simple movements to regain a sense of control.
So today after she finished breakfast, she practiced grasping with her left hand in her room.
The reason she practiced with her left hand was because she lost control of it faster than her right hand, and while her right hand could still perform some simple movements until the third edit, her left hand hadn't been used for a long time.
Aine sighed softly and looked at her left hand. "Really? I wonder when it will recover to the same level as my right hand."
She stretched out her left hand tremblingly, closed her five fingers, and slowly grabbed the mobile phone on the bed. She exerted her muscles and lifted it up, but when the phone was a few centimeters away from the bed, she felt her left hand suddenly lose strength and the phone fell on the bed again.
"Failed again." Aine lay down on the bed and turned to look at the phone next to her. When would she be able to hold the phone with her left hand for a long time? Not saying how long... even ten minutes would be fine.
Thinking of this, Aine turned back to face the ceiling and stared at it quietly. She had already practiced for two hours today, but the longest she could hold was just over a minute.
"jingle."
Just when Aiyin was getting discouraged, her phone suddenly lit up.
“Hmm?” Aine turned around and picked it up with her right hand. “It’s Umirin, what’s going on?”
Although Aiyin was surprised that Hailing would suddenly send her a message, she still opened the chat box.
[Hailing: Do you have time?]
[Aine: Yes, what's wrong?]
[Hailing: Do you want to go out for a walk?]
"Eh? Umirin suddenly asked me out? Did something happen?" Although Aine was confused, she still replied with an "OK".
[Hailing: I'm already at your door.]
[Aine:?]
What? Already here? So you came to my house and sent the message?
Aiyin came out of the room with a confused look on her face, walked slowly to the door, opened it, and Hailing was there as expected.
"Shall we go?" Hailing put away her phone and crossed her arms over her chest.
"Let me change my shoes."
A few minutes later, Aine changed her shoes and followed Hailing out of the house.
On the way, Hailing's speed was very slow. Aiyin naturally noticed Hailing's little movements. She was very grateful in her heart: "By the way, Umirin, why did you come to see me suddenly?"
Hearing this, Hailing's face was very calm. She replied softly: "We are friends, but we haven't really gotten along well yet."
Aine blinked, she listened to this and nodded thoughtfully, indeed, what Umirin said was true, although we are friends, we don’t have much time to communicate, most of the time is because of Rikki and ALS.
"You're the one who sent me the message, right at my doorstep?"
"Ah."
"Aren't you afraid that I'll go out and play with Rikki and the others?"
"..." Hailing fell into a brief silence before she spoke, "Really?"
Seeing Hailing's calm expression, Aine was confused. What did Umirin mean by this? Did she...know I was home in advance? Was she asking Rikki?
Compared to Aine's confused expression, Hailing kept a calm face, but her heart began to churn and she felt a little embarrassed.
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