Cyber ​​Heroes

Chapter 592

Xiang Shan looked at Nia Guti in shock: "You mean, such an embryo can survive? Animals and plants mixed together?"

"At the embryonic stage, a living thing is just a group of cells, and the tissue has just begun to differentiate." Nia Guti spread her hands: "Because the volume is small enough, it is enough to rely on the cells to passively absorb the surrounding nutrients, even if no organs are differentiated. Survival. However, organisms that are too distantly related are likely to have problems with the process of organ differentiation."

Xiang Shan patted his head: "Is this... quite sci-fi?"

"Sci-fi shit." Yawgmoth said disdainfully, "Sci-fi research started decades before we were born. Are you talking about sci-fi? Steampunk?"

"Strictly speaking...well." Nia Guti said: "Since the 1970s, scientists from all over the world have been studying heterogeneous chimeras, such as sheep-goat chimeras, rat-mouse chimeras. In the 21st century At the beginning, it mainly studied human-animal chimera, hoping to create animals that can provide organ transplants. The company that cooperated with us on the matter of 'monkey'...the Institute of Primate Translational Medicine in central Yunnan , is quite famous for its work on primate chimeras."

Xiang Shan was shocked again: "Is Crouching Tiger, Hidden Dragon so far in our cooperative institution? No... this research is so early..."

He really felt that this kind of sci-fi style of painting was created after Yawgmoth made a major breakthrough in basic theory.

"Grafted plants are a kind of chimera. In fact, this phenomenon was first recorded by horticulturalists." Nia Guti shook her head: "Not to mention plants, natural chimeras also exist in the animal kingdom-including Humans. In the mother's womb, fertilized eggs occasionally develop into different embryos, which may then reintegrate together before a certain stage. Many people are natural chimeras, but they never know it in their lives .”

"Of course, there are occasional oddities—for example, someone whose reproductive organs just happen to come from their fraternal twin sibling. When such a person does a paternity test, they will always conclude, 'this child My biological father is the brother of my one-mother sibling'."

"Compared to me, this kind of research has almost no technical content." Yawgmoth sneered at this: "Actually, the chimera research is because the immune system has not yet come online. I remember that the human-monkey chimera in vitro embryo was 20 days ago. All of them have to be executed, right? And some studies have shown that no traces of dendritic cells can be detected in fetuses after No.12 weeks."

"And at this stage, the dendritic cells of the fetus are not used to defend against the outside world, but to inhibit the generation of its own immune cells, so as to avoid mutual attack between its own immune function and the mother."

Dendritic cells, an immune cell responsible for antigen presentation, can efficiently ingest, process and present antigens, are responsible for activating initial T cells, and are at the center of initiating, regulating, and maintaining immune responses.

"To put it simply, in order to avoid miscarriage, the immune system is in the 'exemption period' during the embryonic development stage. At this moment, almost nothing will trigger the alarm when it comes into contact with things. This is how the so-called chimeras survive." Yawgmoth continued. : "In fact, until after the baby is born, this 'weak alarm' situation will continue to a certain extent for a period of time. There are theories that some people are prone to allergies because they have been too clean during this period and immune The system 'white list' is not long enough."

Xiang Shan feels that his concept of hygiene has been subverted: "So there is a scientific basis for 'you don't get sick if you eat dirty'?"

Nia Guti reminded: "Only infants and young children... And this also means that they are prone to whitelisting really dangerous pathogens, and childhood may become sickly."

At this point, Xiang Shan probably understood what Yawgmoth meant.

"You mean..."

"This is the optimal solution C." Yawgmoth said: "Find a way to reverse the life cycle of the immune system, allowing the immune system to temporarily return to the 'embryo stage'. The drugs needed for this technology are various drugs that target Dedifferentiation of immune cells induces signaling molecules. They are responsible for knocking in instructions to the immune system - reinvoking the 'state of embryonic development'."

Niya Guti pondered for a moment: "The feasibility should not be low?"

Xiang Shan asked, "What about the time?"

"The division of immune cells is very vigorous, and life activities are active, so the transformation will be very fast." Yawgmoth said: "I haven't done the experiment yet, so I can't give the exact number. But it will probably be within [-] days It can be completed within seven days-seven days is not impossible."

Xiang Shan pressed his head: "This is too fast..."

"And there is another advantage." Yawgmoth said: "The life cycle reversal of the immune system is a process. During this process, memory cells will gradually eliminate the antigens they have recorded. Non-specific immune cells will be produced more and more. Slower. Their immunity will return to the embryonic stage after a period of time. There is no need to use sterile wards or even hospitalization in the early stages of this reversal phase."

"Then these friends will find that the dietary allergies that have troubled them for many years have disappeared. But at the same time, the past vaccines will be in vain."

"The drug..."

"It's just a few signaling molecules." Yawgmoth was very confident: "After I completed the research on the basic theory, this is the easiest drug to find a synthetic method."

Xiang Shan put his head in his hands: "God...it's actually a perfect plan?"

He almost wanted to stand up and give Yawgmoth a high five.

However, the memory of being severely cheated just now made him instinctively keep alert.

Xiang Shan said: "Yoge, let me confirm again... this drug should not cause the life cycle reversal of other tissues, right? For example... um, the nervous system? If the nervous system is reversed to infancy, no, reversed to Puberty is scary enough."

"Theoretically speaking, different factors should be used to issue 'instructions' for different tissue cells. Past experience has also shown this point. To trigger this function, a single instruction is not enough." Yawgmoth thought: " A command set that can act on the whole body...is it possible?"

Xiang Shan said: "What about 'aging'?"

"Only some tissues have returned to the past state at the level of cell function. At the micro level, the telomeres that control the lifespan of cells have not been replaced, and the traces caused by the years still exist. At a more macro level, the body as a whole will not happen. Changes. The elderly who receive this therapy will at most become "an elderly with some cells functioning like a fetus."

　It's the end of the month, right...

　　
　
(End of this chapter)