Cyber ​​Heroes

Chapter 597 Therapy
In 2044, Yawgmoth stated that it was difficult for him to understand why anyone would reject the HIV infection of Plan A.

Because a person, no matter whether he chooses the "improved HIV infection" of plan A, the "drug, radiation destruction" of plan B or the "18:3 medicine that reverses the life of the immune system" that has not yet been developed at the stage of "immune system offline" Cycle", in the second stage of "gene implantation", all have to face the virus cocktail.

And the virus cocktail must contain a thing whose "prototype" has a much higher lethality rate than HIV, that is, rabies (improved version).

Different viruses have different affinities for different cells.

Rabies virus is a neurotropic virus.It has an extremely strong neural affinity.Generally speaking, after rabies enters the body, it can be transported along the reverse axon of the nerve without blood circulation, and violently blasts into the brain.

Compared with many viruses belonging to the herpesviridae and picornaviridae that belong to neurotropic viruses, rabies virus has a huge advantage, that is, "fast".

It almost specializes in nerves, it can penetrate into the brain at the fastest speed, and spread quickly.

From the onset of the disease to the death of the patient, it hardly takes more than 24 hours.

As for the "incubation period", that is, the period from "infection to the discovery of symptoms", in fact, it only depends on the amount and concentration of the virus received by the infected person.

If a sufficient amount of pathogens is artificially injected, the incubation period can be shortened to a relatively short time.

What's more, the incubation period of rabies is inherently very short-the "ten-year incubation period" advertised in the past, the latest research believes that it is more likely to be the result of incomplete records or false positives.

It can enter the neuronal system very quickly.

And that's exactly what genetic modification surgery needs.

Due to the difference in metabolism, cells in different parts of the human body have different speeds of renewal.

Nerve cells are undoubtedly the slowest of them all.

The lifespan of nerve cells is almost the same as that of the human body itself, they will hardly divide, and the damage will not be easily repaired.

This is entirely to ensure the stability of the neural network structure, so the repair function is abandoned.

Its proto-oncogene is fairly inactive.

This is why neurons rarely become cancerous.

And this characteristic also causes the transformation rate of the nervous system to be much slower than other parts of the physical body during the metallization operation.

The remedy is the rabies virus.

In theory, this is indeed feasible.Anyway, no matter what kind of pathogen it is, it can't do anything in the face of the extremely high body temperature of the reference person, and it will eliminate it by itself, so as long as it survives this test, Yawgmoth will be safe.

But here is the problem.

The mortality rate of rabies is also very high, close to [-]%.

The blood-brain barrier protects the brain from external infections, but also keeps most immune cells out.

If ordinary immune cells appear near the central nervous system to kill virus-infected cells, it will do more damage to the neuron network than the virus-the principle of immune cells is "kill if you are likely to be infected".

Only a subset of antibodies can enter the brain.

But this little antibody, and the microglia that serve as the "guardian army" of nerve cells, are not enough to reverse the ravages of rabies virus.

Once rabies occurs, the mortality rate is close to [-]%.

Generally speaking, if you want to avoid death from rabies, you can only produce enough antibodies to suppress the virus before the onset of the disease.

But the method Chen Feng proposed...is undoubtedly to make it sick.

After all, this requires the simultaneous transformation of neurons throughout the brain.

Since the brain controls every aspect of the body, it is easy to die if the brain is damaged.The condition for "morbidity and death" of rabies is actually "the proportion of infected (destroyed) cells is sufficient to cause death"

This time is still far from "the whole brain neurons are infected".

In other words, this is equivalent to allowing the person undergoing the operation to live for several weeks in a state of "rabies attack".

On the basis of ensuring the speed of virus transfer, it is also necessary to ensure that the virus will not damage the brain neural network, or "cannot be lethal before the transformation is completed", so that after the transformation is completed, the body temperature of the baseline will spontaneously clear the virus.

This is undoubtedly a daunting task.

But it's not "impossible".

Others from the Superhuman Enterprises retrieved Yawgmoth's research records.In order to complete the "virus cocktail" and to give an explanation to the investors in HIV research, Yawgmoth has made many "power-reduced versions" of the virus.

He has a set of mature methods that can be used against most viruses.

Yawgmoth always likes to start from the underlying principles and think deeply.

So, there is only one problem left.

They can only cultivate the rabies virus with reduced destructive power according to that procedure, but they don't have time to complete several phases of experiments according to the new drug development process.As long as it is determined that "primate experimental animals can survive for several days after the onset of the disease", they have to inject Yawgmoth into it.

They didn't even have time to confirm "whether it will cause irreversible damage to the central nervous system"—at that stage, the "Xiaohuandan Project" also produced signal factors that could be used in the peripheral nervous system.Yawgmoth would not be able to develop reddanase that could safely act on the central nervous system until several years later.

This kind of thing is gambling on the future.Although there is an excuse of "to save people", this is undoubtedly on the edge of ethics.

Take it outside, and it is easy to be attacked.

It is good to succeed, but if it fails, the person who implements this plan will bear the burden of a lifetime.

At this time, Niya Guti unexpectedly stood up and took on this task.Through her contacts, she obtained a bat rabies virus with the lowest destructive power among known rabies viruses.She even excluded most of the assistants from the laboratory, leaving only a few experimenters-these people have very low positions and have no qualifications to "take responsibility".

So is animal testing.

She did almost the whole process alone.

After finding the "improved virus that won't kill the host immediately after the onset", he rushed to Yawgmoth immediately.

In the end, she also used a subarachnoid injection to inject the virus into Yawgmoth's spine.

Even if Yawgmoth died, the responsibility would not spread to others.

The end result was fine.

Although Yawgmoth received all the glory in the field of biology in that era, Nia Guti can also be called a "genius scientist".

Yawgmoth survived without even having any aftereffects - the only problem he faced were a few holes in his head.

The nursing team used two methods to ensure the temperature in his cranial cavity.First, the blood is drawn out from the arteries that supply blood to the brain, and then reinfused after being cooled outside the body.

The second is to directly punch a hole in his skull, and pass the coolant tube through it.

(End of this chapter)