godfather of surgery
Chapter 1048 Born like a summer flower
Chapter 1048 Born like a summer flower
The time it takes for a virus to replicate through division is 6-8 hours, which is an astonishing speed.
About a billion viruses piled together are about the size of a grain of rice. With one virus as the origin seed, it needs to replicate exponentially 30 times to reach about 10 billion. 30 divisions take about 150 hours, or about 6 days.
The virus divides so quickly, so the risk is also high.
If all the split viruses do not mutate, or the changes after mutation are not significant and do not deviate from our expectations, there is generally no problem. This is because the consequences caused by these viruses are already within the experimenter's expectations and control, and the viruses used by the experimenter are also strictly selected and will not cause obvious harm to the human body. For example, the measles virus and vesicular stomatitis virus have minimal negative effects on the human body and are transient.
The most terrifying thing is that the virus may mutate beyond our expectations and control during the iteration process. Once the virus mutates in this way, its harm will be beyond our expectations and control. These mutated viruses can still split exponentially and their number will increase.
If these new viruses have some kind of pathogenicity, once they enter the human body, there is no effective drug to eliminate them, or the human immune system is unable to eliminate them. This is tantamount to infecting the patient with a new viral disease. Of course, the probability of such a risk event occurring is extremely low.
Virus cultivation experiments must be conducted in a biosafety level 3 laboratory, so Lu Xiaolu needs to conduct the virus experiments in the high-level biosafety laboratory of Nandu Medical University. Currently, the stem cell laboratory and tumor laboratory of the Institute of Surgery do not have such conditions, and these two laboratories are not prepared for virus experiments.
When Lu Xiaolu was studying in Germany, he had a lot of exposure to these interdisciplinary fields, so he is familiar with tumor immunotherapy, biological therapy, targeted therapy, and oncolytic virus therapy. This experiment is most suitable for him to do.
The professors at the virus laboratory of Nandu Medical University were very happy to cooperate with Sanbo Hospital, so a cooperation intention was quickly reached. In addition, a Nobel Prize-winning virologist introduced by Professor Brian will soon start cooperation and exchanges with Lu Xiaolu.
Yang Ping and Lu Xiaolu went to Nandu Medical University to inspect the virus laboratory and talked for a long time with Professor Zhang Zhiwei, the director of the virus laboratory. After the talk, Yang Ping and Lu Xiaolu decided to take a few laps around the campus of Nandu Medical University. It was rare for them to come here at other times, but every time they came here, as long as they could spare the time, Yang Ping would take a walk around.
On a tree-lined avenue, Yang Ping saw Principal Rao from afar. He came to the school to handle the procedures for early retirement.
President Rao resigned because of the incident between Guan Ruyan and President Ding. Professor Su Qingyun, the dean of Nandu First Affiliated Hospital, succeeded President Rao as the new president of Nandu Medical University, and concurrently served as the dean of Nandu First Affiliated Hospital.
In fact, President Rao is indeed a good president. He is honest and upright, daring to act, and has the demeanor of a righteous scholar. During his tenure, he made great contributions to the development of Nandu Medical University, implemented many very meaningful reforms, and provided a lot of help to Yang Ping at that time.
When President Rao resigned, Dean Xia, Professor Su, Yang Ping and others invited President Rao to dinner and held a farewell ceremony for him.
From a distance, Yang Ping saw Professor Su and several vice presidents chatting with Principal Rao. A large group of students gathered around them. These students were actually reluctant to leave Principal Rao. When they heard that Principal Rao was coming back to handle the formalities, they spontaneously gathered around and wanted to shake hands with Principal Rao.
Principal Rao also saw Yang Ping. The two of them stretched out their hands from a distance, then walked over and shook hands.
"Professor Yang, how are you doing recently? I heard that you have been conducting experiments on the treatment of tumors with viruses. Professor Zhang Zhiwei in our school's virus laboratory is very good. He has worked in several top virus laboratories in the United States, Britain and Germany, and has made remarkable academic achievements." President Rao is in good spirits and obviously does not have the retirement syndrome of leading cadres.
"Yes, we came here to discuss cooperation on the project with Professor Zhang. How are you now?" Yang Ping was also very concerned about Principal Rao's recent situation.
"As for me, I am retiring and returning to my hometown. Not long ago, I went back to my hometown to worship my ancestors. The local government heard that I had retired and hoped to invite me back to serve as a government advisor in education. For this matter, the county magistrate from my hometown came here three times. I couldn't refuse and agreed to go back to help with education and make use of my remaining energy. It can be considered as having something to do after retirement." Principal Rao said with emotion.
It seems that Principal Rao is also a person who cannot sit still.
"Professor Yang, have you met Professor Zhang Zhiwei?" Professor Su usually calls Yang Ping "Xiao Yang" at home, and now outside, he also calls him Professor Yang in a formal manner.
"Yes, we met and talked for a long time. We just visited the laboratory. I told Professor Lu that it was a rare opportunity for him to come here, so I planned to take a walk around the campus." Yang Ping explained immediately.
More and more students gathered around, including many teachers. The whole road was packed at both ends. The atmosphere was even more lively than when a star appeared. Yang Ping looked around and saw that there were several thousand people, and the number was still increasing. They had spontaneously stood on both sides of the road, leaving the middle empty.
"Principal Rao, we miss you so much!"
I don't know who took the lead in shouting.
"Principal Rao, we miss you so much!" The shouts of the entire crowd sounded like waves, one after another, and finally turned into a uniform shout.
Since he resigned, President Rao has been on leave. Today he came to officially go through the procedures for early retirement. Unexpectedly, he appeared on the campus of Nandu Medical University for less than two hours and attracted so many people.
Principal Rao was a little at a loss at first, then his eyes turned red. He immediately took out a tissue and gently pressed it against his eyes, then waved to everyone.
"I miss you too!" Principal Rao kept waving his hands.
The road here was already crowded with people, and the woods on both sides were also full of people. They all gathered here temporarily after receiving the news. There was no organization, no banners, no flowers, only sincere shouts.
Principal Rao tried to shake hands with the students and teachers who extended their hands, but he was unable to do so.
A black car drove in, and Professor Su said, "The car is here."
"Professor Su, look, it's such a trouble for you. Why bother to arrange a car? I can just take a taxi myself." Principal Rao said while waving to the crowd.
Professor Su opened the car door and said, "It's not a big deal. Let the car from Nandu Medical University take you there again."
"Goodbye, Principal Rao. You must come back often."
Principal Rao looked back and saw the crowd waving at him, then reluctantly got into the car.
-
Sisi's transient dizziness becomes more and more frequent, and the symptoms become more and more obvious. Sometimes when the dizziness is severe, she will have a brief loss of consciousness, but this brief loss of consciousness usually does not last very long, only a few seconds.
Yang Ping knew that her dizziness was caused by an intracranial tumor, which had affected the heartbeat center, causing a short-term suppression of the heartbeat. When the heartbeat is suppressed, the blood output will be reduced or stopped, which will lead to insufficient blood supply to the brain. Dizziness is a reaction to insufficient blood supply to the brain. If this kind of heartbeat suppression continues to worsen, one day the brain will die due to long-term lack of blood supply.
Even if Yang Ping had not told Sisi about her condition, the clever girl knew that it was the final moment, because Yang Ping had not told her about her condition or the next treatment plan, which meant that there was no plan now. She had also prepared herself mentally to face it all calmly.
These days, every time Yang Ping came to make rounds, he would talk to her about the cactus and discuss with her the experience of growing desert succulents. Yang Ping never talked about the condition, and Sisi didn't ask either. They had a very pleasant conversation about the cactus.
The doctors, nurses and students who followed the ward rounds in the morning were very confused as to why Professor Yang did not talk about the patients' conditions during his rounds but only talked about cactus.
Every time he went to check on the ward, Sisi was reading under the window. The ward was well-lit. At that time, the morning sun shone into the ward and onto Sisi's body. She looked so peaceful, calm and composed. Yang Ping really wanted to know what the inner world of this little girl was like, why she could be so calm in the face of death, most adults couldn't do that.
In the afternoon, Yang Ping came to Sisi's ward alone for rounds. Sisi was sitting under the window reading a book again. The golden sunset had not yet faded and was shining on her body. Sisi looked like a beautiful flower.
Yang Ping walked over slowly and Sisi closed the book.
Yang Ping glanced at Tagore's poetry collection and the page she had just read was "Life is Like a Summer Flower".
"Are you scared, Sisi?"
Now there are only Yang Ping and Sisi in the ward. He decides to talk to her. Yang Ping stands next to the cactus.
Sisi smiled, her face flushed with the blush that only teenagers have. "I was afraid before, but not anymore. I've read a lot of books since I got sick. My math teacher once told us that we would learn rules called axioms in middle school. Axioms don't need to be proven, they are correct. I found that there are also two self-evident axioms in medicine, or axioms that don't need to be proven. I don't know if they are right, and I don't know if there are such axioms in other books."
She could actually summarize axioms, and they were medical axioms. Yang Ping was very curious about what this eccentric little girl was thinking about.
"Tell me what you think of this axiom. I want to know whether this axiom is your original creation or just an accidental coincidence with the achievements of your predecessors." Yang Ping smiled.
Sisi thought for a moment and said, "You can't laugh at me when I tell you this, and you can't say it's just childish talk."
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Yang Ping quickly said, "I promise, I won't laugh, and I won't treat it as a child's words."
Sisi lowered her head and thought for a while, then looked up and said, "Everyone will get sick, and everyone will die of illness."
Yang Ping repeated this sentence in his mind and couldn't help feeling surprised. What a smart little girl! She really gave a very profound philosophical interpretation of the disease from a certain perspective.
Everyone will get sick and everyone will die from illness. This is absolutely true.
To borrow a commonly used concept in oncology: the five-year survival rate, in a sense, the difference between normal people and patients, and even between normal people and cancer patients, is only the five-year survival rate, and both are less than 5%.
In simple terms, birth, aging, sickness and death are inevitable for everyone. Everyone will die eventually, it’s just that the age at which they die is different.
At this moment, Yang Ping didn't know what to say. He could only use his efforts to give the little girl a glimmer of hope, even if she didn't need it now. But Yang Ping felt that as a doctor, he had the responsibility and obligation to give terminally ill patients a glimmer of hope, even if it was just comfort or care.
"I am trying a new treatment method, using viruses to carry factors that can kill tumor cells to treat you. These viruses are injected into your body, and they are carried to all parts of the body by the blood. They can penetrate the blood-brain barrier, infect those tumor cells, and then use the deadly factors they carry to kill the tumor cells. Our viruses have been successfully modified. These viruses have been cultivated in the laboratory and will soon be injected into your body."
Sisi always had a bright smile on her face, like an angel: "I said that eyes are windows to the soul. I can see from your eyes that you are comforting me. This kind of treatment plan takes more than ten years from medical design to clinical application, and the success rate is pitifully low, often less than 1%. But I am willing to be your experimental subject. I once said that I am willing to be your wrong answer book."
"Have you read any books or papers on this subject?" Yang Ping was very surprised.
Sisi nodded: "Didn't you get me a library card for the hospital? I often go there to read books and magazines, so I know a little bit."
"You will definitely become a good doctor if you study medicine in the future." Yang Ping encouraged her, although this was just a lie to deceive her.
Sisi pursed her lips and said, "I have a favor to ask you. Have you asked for me? I wonder if the bodies of cancer patients can be donated to medical schools. If so, I want to donate my body to Nandu Medical University as a specimen for medical students. I said before that I want to study medicine with you, but now it seems that I can't do it. If I can donate my body to Nandu Medical University as a cadaver teacher, wouldn't that be another way to enter the medical field and realize my dream?"
Can't empathize!
Yang Ping told himself this in his heart, but he couldn't help it, his eyes were already wet.
"Can you agree to this? This is my last request."
"can!"
Yang Ping turned his head to look at the cactus in the corner. He didn't want Sisi to see him crying. In front of Sisi, he always portrayed himself as a confident and omnipotent big brother.
"Are you a professor at Nandu Medical University?"
"Yes."
Yang Ping deliberately lowered his head and fiddled with the cactus.
"Then you will definitely go to class." Sisi looked very happy.
Yang Ping's voice was a little hoarse: "I have a class every week."
"Is it anatomy class?"
'No, it's Surgery, taught to senior medical students.'
“I see…”
Sisi's tone was a little disappointed.
"what happened?"
"If you take the anatomy class, I can listen to your lectures every week..."
Yang Ping took a deep breath, tears streaming down his face. His throat was blocked by something and he could no longer speak.
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