Homo sapiens

Tian Hemeng proposed a 1 billion procurement plan based on the requirements of the headquarters.

Among them, the quota for imported drugs is 500 million yuan, and the quota for production line procurement is 500 million yuan. They also promised that when they need to purchase drugs from outside in the future, they will give priority to CP Company.

Xie Bin looked at the list of imported drugs in his hand, his eyes almost bleedin' out.

Listed above are [Entecavir dispersible tablets], [Magnesium isoglycyrrhizinate injection], [Diammonium glycyrrhizinate enteric-coated capsules], [Entecavir maleate tablets], [Irbesartan hydrochlorothiazide tablets], [Suvastatin calcium tablets], [Alprostadil Injection]...The import demand for a total of 44 types of drugs.

Some of these drugs are needed by Qingye Pharmacy, and some are needed by Qingye Hospital.

However, Xie Bin does not have the authority to decide on the introduction of production lines, but he estimates that the headquarters will not refuse. After all, if Zhengda Company does not sell it, other companies will.

Qingye Medical requires many production lines, mainly focusing on cardiovascular and cerebrovascular, anti-tumor, orthopedics, analgesia, and supplementation.

As for drugs for liver disease, respiratory system, and digestive system, they are not on the list. These drugs will mainly be developed by Qingye Medical in the future and do not require Zhengda’s production lines.

A total of 13 drug production lines were selected.

After communication between Xie Bin and the headquarters, the two parties quickly reached an agreement that Chia Tai Pharmaceutical would package and sell a batch of drug production lines that were about to be eliminated or had been eliminated to Qingye Medical.

After signing the contract, Zhengda Company's reserves in Qingye Bank rose to more than 500 million.

But Zhengda Company has no idea of ​​withdrawing money. After all, the money must be spent. As the effect of Ai Qingling spreads to the outside world, and many regions have not approved Ai Qingling for sale, this means that within a period of time , Hongsawady, Siam, and Luzon will become the main channels for AIDS patients around the world to obtain drugs.

…

If we talk about the specific AIDS drug - Ai Qing Ling, it only makes people around the world interested.

Then rabid dog killers have become a necessity in many underdeveloped areas.

After all, these underdeveloped areas do not have the conditions to popularize rabies vaccines. Whether it is for people or pets, there is not enough popularization rate.

For example, in Siam, there was a large-scale rabies outbreak in Siam in 2018.

Many people who have been bitten by cats and dogs generally do not have enough awareness of prevention, or think that the price of rabies vaccine is too high, so they do not get the rabies vaccine in time. Then when they get sick, there is basically no cure.

Although the price of rabies killer is very high, its importance has skyrocketed because it is still effective during the onset of disease.

Of course, Tian Hemeng knows that with the current pricing, there are only a few people who are willing to purchase the cooperation of Rabid Buster.

Therefore, the production capacity of Rabies Buster's production line is very low. Even if the production line is fully operational, it can only produce 20,000 boxes a month. What's more, it only operates for an average of 3 hours a day, and the monthly production capacity is only 2,000 boxes.

The production volume is low, and the demand is not high, so the sales price is naturally high.

For this kind of niche medicine, Qingye Medical focuses on a small town near Taunggyi to carry out joint production.

Usually, one kind of drug is produced normally for a week, and then the employees are transferred to the next production workshop to produce another kind of drug, and the cycle repeats.

Using this kind of production plan is also a last resort.

After all, this is the fate of niche drugs. The market is so big that it is too difficult to stably maintain a production line at full capacity.

Otherwise, Qingye Medical would not have limited sales of Ai Qingling, because it was worried that the market would be saturated and the production line would be scrapped.

This is also the reason why many large pharmaceutical companies do not like to develop radical drugs.

Everything is for profit.

…

Also for profit.

Hundreds of generic drug companies in Tianzhu have also taken action recently.

A large generic pharmaceutical company located in Mumbai has purchased some Ai Qingling through Tianzhu people in Yangon.

In the laboratory, boss Ali eagerly asked: "Dr. Kesha, how is the research going?"

Dr. Kesha, who was wearing a white coat, shook his head: "Mr. Chairman, I'm very sorry. I'm afraid we can't copy this medicine."

"Why?" Ali asked unwillingly: "Is it because our equipment is not good?"

"Mr. Chairman, this is not a problem with the equipment, but because we don't have the raw materials." Dr. Kesha spread his hands.

Ali frowned: "Raw materials?"

"Yes, it is the raw material. This new drug requires the use of specialized bacteria, similar to bacterial strains such as penicillin and streptomycin."

"Then let's go buy the strains!"

The corner of Dr. Kesha's mouth twitched slightly: "Haha, the key is that Qingye Medical has not announced which bacteria it uses as raw materials. According to my experience, it is definitely not a common medicinal bacteria."

"Damn it! These greedy vampires are hiding such crucial information."

Haha, Dr. Kesha complained secretly, you want to copy someone else's new drug, and you blame others for not publishing the technical details, please don't be so shameless.

Ali suddenly had a whim: "I heard that antibiotics can now be synthesized artificially. Can we try this method to produce them?"

"Uh...Mr. Chairman, the active ingredients of the other party's new medicine are all macromolecular organic compounds. To synthesize them artificially, you must first figure out which part of the structure of this macromolecule is responsible, and this kind of research requires a lot of funds. The research time also takes a long time..." Dr. Kesha explained helplessly.

As soon as Ali heard that it would require a lot of money and a long time, he looked disappointed.

Generic drug companies like him rely on copying new drugs developed by others. It is basically impossible to expect them to invest heavily in developing a drug with an uncertain future.

In fact, it is not just Tianzhu generic drug companies that are secretly studying imitation.

Even major pharmaceutical companies in Europe and the United States are secretly studying how to imitate them.

It's just that they all encountered the same problem.

That is what kind of bacteria Qingye Medical used to isolate these three new antibiotics. Now European and American pharmaceutical companies have not found similar macromolecules, so they can only study the structures of these macromolecules, hoping to find some effective ones. anti-virus structure, and then learn from and improve it.

So what kind of bacteria does Qingye Medical use?

The answer is genetically recombinant phages. These phages have been modified beyond recognition by Li Qingye, and then these phages are used to continuously fight with HIV to select phages that can resist and kill HIV.

In other words, as a strain that produces new antibiotics, it is not a naturally occurring bacterium. Other laboratories cannot obtain this genetically recombinant bacteria, and they cannot imitate it in a short time.

This is just like when penicillin first came out, those high-yield strains were the core secrets of various pharmaceutical companies and even countries.

Without high-yield strains, the production cost of ordinary penicillin is comparable to gold.

The bacterial strains currently used by Qingye for medical treatment do not even exist in nature, and other laboratories cannot even extract a small amount. Faced with this situation, how to imitate them?

You must know that this is not an ordinary inorganic chemical drug, but an organic macromolecule, and it is very difficult to synthesize it artificially.

This is also one of the advantages of target antibiotics. Without powerful enough genetic technology, there is no way to imitate target antibiotics in a short time.

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