Hearing this, Lenai nodded slightly and said nothing more. She just sat quietly against the wall, circling her index finger on the floor.
Noticing that Su Shi on the other bed hadn't moved for a long time, Mu called out softly, "Su Shi..."
But Su Shi still didn't respond. Seeing this, Mu stood up, sat next to Su Shi, and poked her shoulder: "Su Shi?"
"Huh?" Su Shi raised his head in confusion, "What's wrong?"
"I called you just now... but you didn't respond..." Mu's voice was very soft.
"Sorry...I was distracted." Su Shi lowered his head.
Mu gently placed his hand on Su Shi's shoulder: "Don't worry..."
Hearing Mu's comfort, Su Shi was slightly stunned. She never thought that one day she would be comforted by Mu.
She forced a smile at the corner of her mouth, but it obviously didn't suit Su Shi's haggard face. She spoke softly, her voice hoarse: "Well, I know."
As Su Shi finished speaking, the entire ward returned to its previous silence, and the ticking of the clock was still shrill.
Time passed bit by bit, and when the hour hand on the clock reached "3", the door of the ward was knocked without warning.
The crisp sound interrupted the silence in the ward and everyone's sad mood.
The next moment, the nurse pushed open the door and took a quick look. Seeing that everyone was awake, the corner of her mouth twitched: "Well, although I know you are worried about the patients, you should rest when you need to."
After a pause, the nurse continued, "Although it's cruel, you won't be able to help if you don't sleep. Why don't you get some rest? We nurses will come and call you if anything happens."
After the nurse finished speaking, Miao Meng, who was closest to the ward door, rushed to her and said, "Um, nurse, how is Aizi now?"
"The patient is no longer in critical condition and has been transferred to the ICU. However... during this period, the cytokine storm may recur at any time, so you still need to be mentally prepared."
"That means... everything is fine now?" Xiangzi got down from the hospital bed, and the light returned to her eyes.
The nurse shook her head. "That's not right. He's only out of critical condition now. I'm not sure if there will be any accidents later."
"Thank you, nurse." Su Shi felt that his breathing was finally smoother.
"Nothing." The nurse shook her head and glanced at everyone again. "Rest if you need to. We'll let you visit the ICU later."
After saying that, the nurse closed the door of the ward and left.
Aine's mother finally felt relieved. At least Aine was no longer in critical condition. It was a blessing in disguise.
Aine's father gently hugged Aine's mother, patted her shoulders softly, and comforted her silently.
"That's great..." Chu Hua covered her face with her hands and took a deep breath. Her depressed mood finally eased. She felt that if she had heard the news later, she would have been hospitalized because of emotional problems.
Seeing Miao Meng still pacing, Hailing reached out and grabbed her shoulders: "Okay, stop wandering."
Looking up at Hailing, Miao Meng nodded slightly without saying anything more.
Li Xi squatted beside Lenai and Deng, and comforted them softly: "Don't worry, everything will be fine."
After hearing the nurse's news, Deng and Lenai gradually believed Li Xi and nodded in agreement.
Mu sat beside the bed, turned his head to look at the bed, and let out a long sigh: "Mortis... Aine-chan, she is no longer in critical condition..."
"I know, so Xiao Mu, I have been advising you not to be too sad, right?"
"Ah."
Chapter 386 The Second Storm Attack
At three o'clock in the morning, Aiyin was carefully transferred to the ICU.
There were no operating room shadowless lights here. Instead, there were dense monitoring equipment surrounding the bed and the dim light emitted by life support equipment. Various tubes and wires were entangled around Aine's pale and thin body.
The ventilator hissed rhythmically, doing the work for her tired, battered lungs.
The director of the immunology department, the ICU doctor, and Dr. Yamada stood by Aine's bed, quietly watching the girl who was ravaged by the cytokine storm.
"Let the nurse stay here to take care of him. The three of us will go and draft a recovery plan for the patient. We'll call everyone in the department for a meeting in the morning." The director of the immunology department glanced at the two of them.
Seeing the two nod, the director of the immunology department turned and walked out the door.
The clock in the ICU ticks exceptionally slowly.
At dawn, Aiyin fell into a deep coma due to the effects of sedatives, and all indicators were barely maintained at a minimum level with the support of drugs and machines.
The doctors and nurses in the ICU didn't dare slack off for even a moment, taking turns monitoring Aine around the clock, fearing even the slightest sign of trouble. Meanwhile, various departments held several meetings to discuss Aine's recovery plan.
Time passed bit by bit, and soon it was the next night, and there seemed to be a glimmer of hope in Aine's condition.
The nurse in the ICU who had been monitoring Aine reported the situation to Dr. Yamada with surprise: "Dr. Yamada, little Aine's spontaneous breathing has recovered. The ventilator support parameters can be slightly lowered."
After hearing this, Dr. Yamada in the conference room breathed a sigh of relief. After telling the people in other departments about the situation, a hint of relaxation appeared on Dr. Yamada's tense face.
The head of the immunology department also breathed a sigh of relief: "In this case, the situation has begun to gradually improve, but we still need to be prepared. We don't know when the cytokine storm will occur again."
Hearing this, the others nodded. Although the doctors in the conference room came from different departments, they had almost completed all ALS surgeries and naturally knew these things.
In the ICU, the monitor screen was dimly lit, and compared to yesterday, all the values had crossed the minimum limit and began to move in a stable direction.
The nurse had just finished recording the patient's vital signs for an hour, breathed a sigh of relief, and wrote the words "relatively stable" on the record sheet. The corners of her mouth rose slightly, with a hint of relief.
The moonlight filtered through the gaps in the blinds and fell into the ward, casting a few pale streaks of light.
Just as the nurse turned around and was about to put the record sheet back to the duty room, the sharp sound rang out again without any warning.
“Beep! Beep, beep, beep!”
The nurse turned around and saw that the green waveform on the ECG monitor suddenly rose and became sharp. The number representing the heart rate soared from 90 to 160 in an instant, and was still beating wildly!
Almost at the same time, the bar graph of the blood pressure test was cut in half, from the barely maintained 100/60, to an instantly glaring bright red: 70/40 - and still dropping!
Sharp, shrill alarms rang throughout the ICU, and the ECG monitor, blood pressure monitor, and CRRT console exploded at the same time, drowning out the whine of the ventilator and other sounds.
Seeing this, the nurse hurried out of the ward and ran towards the doctor's duty room.
Of course, the doctor sitting in the ICU duty room also heard this shrill sound. He jumped up from his chair, and the thermos cup on the table was knocked over by his violent movement, and the scalding coffee splashed all over the floor.
He didn't care about these things and rushed out of the duty room. He saw the nurse running out of the ward and trying to call for help. Without paying any extra attention to her, the doctor rushed into the ward and came to the bedside in one step.
The doctor's bloodshot eyes swept across all the screens in an instant, his heart pounding - that was not just a physiological reaction, but also the experience he had accumulated over many years of working in the ICU: a secondary cytokine storm.
"Doctor, Aiyin's temperature has reached 39 degrees." The nurse's voice was filled with tears.
"CRRT alarm, transmembrane pressure rises sharply! High risk of filter coagulation!" The doctor operating the CRRT spoke in an urgent voice.
"Doctor, subcutaneous! New large bruises appear on the neck and arms! Increased bleeding from the jugular vein catheter!" The nurse's new report was like a heavy hammer, hitting the doctor's heart hard.
The doctor's eyes were fixed on the newly updated coagulation function report: D-dimer—off the charts! Fibrinogen—barely detectable! Platelet count—plunging!
Experience quickly determined it, and the doctor shouted, "DIC! The core of the storm has shifted to the coagulation system! Level 3 storm! Quick, prepare the coagulation storm plan!"
After saying that, the doctor turned to look at the nurse and said, "Go get Dr. Yamada, the immunology department, and the hematology department!"
"Yes!" The nurse rushed to the communicator, her voice cracking.
Although the doctor wanted to curse inwardly, he held it back and looked at the nurses who rushed into the ward: "Open a second central venous access! Quick! Norepinephrine, immediately! Bring the blood pressure back up!"
Following the doctor's orders, the nurses' hands formed a shadow, tearing open the packages, connecting the tubes, and starting the pumps, their movements precise to the millimeter.
Ice-cold liquid and powerful blood pressure-boosting drugs were forcefully injected into Aine’s circulatory system, which was on the verge of collapse.
"Stop the heparin pump immediately!" The doctor turned and said to a nurse, "Fresh frozen plasma! Target fibrinogen! Cryoprecipitate! Platelets! Request as many as you can! Go to the blood bank!"
Immediately, the doctor turned his head sharply, his gaze fixed on the nurse in charge of the blood transfusion. "Keep a close eye on the D-dimer! If the D-dimer continues to rise above the limit and there's no active bleeding, immediately start a small dose!"
“Increase the intensity of CRRT!”
The doctor's series of orders came in a rush and the nurses and other doctors were doing their own work according to his orders.
Soon, Dr. Yamada arrived without even having time to put on his white coat, and the director of the immunology department also arrived.
They had not slept for two days and one night since the microenvironment regulation surgery began. Just as they were about to rest, they received a call from the ICU.
The second storm came swiftly and cunningly. It didn't have the absolute peak of the first Category 4 storm, but it struck precisely at Aine's organs, which had just been severely damaged and had yet to recover.
Liver and kidney functions deteriorated again, and the ECMO circuit that had just been removed had to be urgently re-established.
Dr. Yamada knew what had happened when they first spoke on the phone. He turned around and asked the nurse who had just called them, "Has the hematology department not arrived yet?"
"Not yet." The nurse shook her head.
"Director." Dr. Yamada glanced at the head of the immunology department. "Our neurology department evaluated the remaining CAR cells and found weak activity signals."
"I understand." The director of the immunology department nodded. He looked at the doctor in the ICU, who noticed his gaze and nodded slightly.
Without hesitation, the head of the immunology department began giving orders.
Chapter 387: The remaining surgical efficiency is very low
About twenty hours after the second alarm was sounded, the curves symbolizing the inflammatory storm finally showed signs of decline again, like exhausted beasts.
The upward momentum was firmly curbed, and it slowly and continuously fell back. At the same time, the coagulation indicators tended to stabilize, and the trend of deterioration of organ function was also stopped with difficulty.
The director of the immunology department and Dr. Yamada took off their glasses that were covered with sweat and fog, and rubbed their brows tiredly. They had not rested for three days and two nights. Fortunately, there were doctors from the ICU and people from the hematology department to help them.
Dr. Yamada took a deep breath, his voice hoarse but filled with unquestionable certainty: "The storm... has subsided."
As soon as he finished speaking, he sat down on the ground. The long-term fatigue made him unable to think. During the operation, he relied entirely on the instructions of the director of the immunology department and the ICU doctor and worked with muscle memory.
However, the head of the immunology department didn't look too good either. He slowly sat down on the chair, looking at the doctors and nurses in the ICU: "I'll leave it to you now."
Hearing this, the tense demeanor of everyone in the ward relaxed a little, and a sense of relief filled the air, diluting a lot of the solemnity.
The victory of the second storm was harder to come by than the first, but victory was theirs.
After resting for a day and a night, Dr. Yamada and the head of the immunology department finally recovered. For the next two days, they kept a close eye on Aine's monitoring equipment.
Three days after the second storm was cured, Aiyin's inflammatory indicators finally stabilized within a safe range, and her organ functions showed obvious signs of recovery. At the same time, ECMO and CRRT were successfully evacuated.
The morning sun shone into the corridor as Dr. Yamada walked out of the ICU and headed towards the inpatient department.
Arriving at the ward, Dr. Yamada knocked gently on the door. After waiting for a moment, Aine's mother gently opened the door.
Aiyin's mother's face was pale, her eyes were red and bloodshot, and her voice was very soft: "Those girls are still asleep."
Doctor Yamada nodded slightly. He also knew that Xiangzi and the others had not slept well these days because of Aine's matter. They finally fell asleep, so he naturally didn't want to disturb them. Waving his fingers, Doctor Yamada signaled Aine's mother to come out.
The latter gently closed the door and walked into the corridor, her eyes filled with hope: "Doctor Yamada, Aine..."
Dr. Yamada nodded gently. "The secondary storm has subsided. Chihaya's inflammation indicators are now stable within a safe range, and her organ functions are beginning to recover. Don't worry."
Hearing this, Aine's mother heaved a sigh of relief. She patted her chest, and her anxious heart finally settled down.
As early as the day when the second storm broke out, the ICU nurse came to the inpatient ward and asked her to sign a critical illness notice. Aiyin's mother no longer dared to recall how she felt when she saw two critical illness notices in just a few days. She was afraid that one day she would be admitted to the hospital because of this kind of shock.
"But Aine-san, I have something else to tell you." Dr. Yamada's expression suddenly became serious.
Seeing Dr. Yamada like this, Aine's mother started to worry again: "What?"
"Although Chihaya has now survived the critical period, the planned microenvironmental regulation surgery has been destroyed by the cytokine storm, leaving only about 10% of its effectiveness..." Dr. Yamada nodded slightly. "I'm not sure if surgery will be needed in the future. We need to wait until Chihaya's body recovers a bit before going to the neurology department for a full checkup."
“Eh?” Aine’s mother took a few steps back, her back hitting the wall. Her pupils trembled violently, and she shook her head dully. “Do I still need surgery? Can I…can I not do it?”
“Dr. Yamada, I beg you…” Aine’s mother staggered to Dr. Yamada and reached out to grab his sleeve. “I really can’t accept this…”
"Then... after Chihaya wakes up, you can discuss this with her." Dr. Yamada sighed. "If surgery is really needed later, you two need to reach a consensus."
Gently pushing Aine's mother's hand away, Dr. Yamada said calmly, "You can visit Chihaya-san in the ICU this afternoon."
After saying this, Dr. Yamada turned and left.
Watching Dr. Yamada's receding back, the fear and despair that had been accumulating in Aine's mother's heart finally burst forth. She held onto the windowsill, her body slowly sliding down the cold wall and sitting down, hot tears pouring out of her eyes.
……
When Aiyin's mother calmed down and returned to the ward, Xiangzi and Sushi had already gotten up. They looked up at the door, and Sushi was the first to speak: "Auntie, why did you go out?"
Aiyin's mother nodded slightly, her face looking haggard. "Doctor Yamada just came."
"Eh?"
Xiangzi and Sushi were startled and immediately jumped off the bed, staring nervously at Aine's mother. They said in unison, "Auntie, what did Doctor Yamada say? How is Xiao Ai (Aine-chan)?"
"Dr. Yamada said the secondary storm has been suppressed."
After Aiyin's mother said this, Xiangzi breathed a sigh of relief: "Fortunately."
Aine's mother forced a smile. "He said Aine's inflammation levels are stable and within a safe range, and her organ functions are beginning to recover. He told us not to worry."
As soon as the words fell, Chu Hua's voice broke into the conversation between the three people: "Then...is there anything else to say?"
The three of them turned their heads and found that the others had woken up without them noticing.
Aine’s mother nodded. “Yes… Doctor Yamada also said that although Aine is now past the critical stage, the efficiency of the surgery has been reduced by about 10%…”
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