Similarly, the ECMO team also began to try their best to provide Aiyin with continuous extracorporeal respiratory circulation to maintain her fragile life.
"Use phenylephrine to maintain blood pressure! Use ice packs to cool down physically, quickly." The director of the immunology department almost shouted the order. He took a deep breath and forced himself to calm down. The beads of sweat that instantly secreted from his forehead were quickly wiped away by the circulating nurse to prevent them from dripping into the sterile area.
But after doing all this, except for body temperature, the other lines on the screen that represent vitality continued to decline desperately and rapidly...
The instrumentation doctor's voice trembled slightly: "Directors, the patient's temperature has reached 41 degrees Celsius, and his blood pressure can no longer be measured."
"Ventricular fibrillation..." The head of the anesthesiology department said in an icy voice, "Defibrillator! 250 joules, quick!"
Upon hearing this, the instrument nurse hurriedly handed him the defibrillator, and the director of the anesthesiology department snatched the defibrillator from the instrument nurse.
"boom!"
Aine had already lost consciousness due to the powerful cytokine storm. The powerful electric current passed through Aine's thin body, and she bounced up and down from the operating table.
On the ECG monitor, the frantic ventricular fibrillation waveform only calmed down briefly.
The head of neurosurgery watched all this with a frown on his face. He couldn't offer any help at this point. The two other directors before him were far more professional than he was in dealing with this kind of situation. He turned to the doctor beside him and said, "Go give this child's family a critical illness notice."
"Yes."
Without any time to worry about the critical illness notice, the director of the anesthesiology department frowned, his forehead covered with dense beads of sweat: "300 joules, continue!"
……
The doctor took the critical illness notice at the door. The head of neurosurgery had already signed his name on it. After the doctor filled in the time, he pushed open the door of the operating room. As soon as he came out, the doctor saw the group of people sitting outside - Aine's parents and the group of girls.
The doctor calmly glanced at the crowd. Before he could speak, Xiangzi jumped up from the bench and came to him almost instantly: "Doctor, how is Xiao Ai?"
The doctor didn't answer, but instead looked at Aine's parents: "Are you the patient's parents?"
Hearing the doctor's voice, Aine's mother nodded: "Yes, I am her mother, and this is her father."
"That's good. Sign the critical illness notice here." The doctor didn't say anything extra and just handed the critical illness notice to Aine's mother.
"Huh?" When Aine's mother heard this, she felt a buzzing sound in her head. She just stood up, but her whole body sat down on the bench like a puppet with its strings cut.
"Slow down!" Aine's father protected her head in time, preventing her from hitting the back of her head.
"Um... Doctor, a critical illness notice? Could it be that... Aine-chan..." Su Shi felt as if her throat was being strangled by an invisible big hand, and she couldn't breathe at all.
"Yes." The doctor nodded, his eyes calm. He was used to this kind of thing. "The patient is critically ill and his life is in danger at any time."
Seeing Aine's mother like this, the doctor handed the critical illness notice to Aine's father.
Seeing this, Aine's father took the critical illness notice and looked at the black and white words in front of him in disbelief. Although he had thought about signing such a thing before, when the moment really came, he only felt that his whole body was shaking.
"Chihaya Aine is being treated in our hospital's neurology department and has been diagnosed with ALS... Despite active treatment, her condition is currently worsening..."
Aine's father could no longer read the content that followed. He tremblingly took out the pen and signed his name, time and other information.
"Sorry for the trouble." After watching Aine's father sign, the doctor returned to the operating room with the critical illness notice.
Watching the doctor's back as he left, Aine's father instantly looked a dozen years older. He slowly sat down on the bench, his whole body shaking uncontrollably. He couldn't believe that he had actually signed his name on his daughter's critical illness notice.
“Sushi…” Deng’s voice was filled with tears, “Aine-chan…”
After hearing the sound of the lamp, Su Shi immediately opened her arms and hugged her, comforting her softly: "Xiao Deng, it's okay."
Mu stood blankly by the wall, tears already streaming down her face. Xiangzi saw this and gently wiped them away for her: "Mu, don't worry. Xiaoai has always had good luck. She will...will be fine."
It sounded like Xiangzi was speaking to Mu, but also like he was speaking to himself.
Chuhua clasped her hands tightly and slowly walked to Aiyin's mother: "Auntie... don't be sad, Xiaoai... it will be fine."
"Uncle, don't be too sad." Li Ying Oyi Fin Si Jiu Si Jiu Ba Xi squatted beside Ain's father. Although he was very scared in his heart, Li Xi knew that he should not show his vulnerability at this time.
"Haizi..." Miao Meng looked at Hailing uneasily.
"It's okay." Hailing patted Miaomeng's shoulder gently, "Believe in Aiyin, she will get through it."
After comforting Miao Meng, Hailing looked up at Lenai who was standing there in a daze. Lenai had been standing there since the doctor took out the critical illness notice.
"Lena..." Hailing walked up to Lenna and called softly.
"Will Aiyin... leave us?" Lenai grabbed Hailing's sleeve tightly and looked at Hailing with a panicked expression.
Looking at Lenai's strange eyes, Hailing turned her face away, her voice trembling slightly: "No..."
Chapter 384 Rescue (still owes zero chapters)
An electric current even stronger than before passed through Aine’s body.
"Bang!" Another violent bounce.
Unfortunately, it was of no use. The curve representing the heartbeat on the screen became weaker and weaker.
Time was stretched out second by second amidst the sharp alarms and the hoarse shouts of the doctors...
After the electrocardiogram struggled for a few times, it finally became a cold, straight, lifeless line.
"drop----"
The ECG monitor emitted a soul-piercing, cold, and long monotonous beep.
The voice seemed to have a physical body, instantly freezing all the chaotic movements and sounds in the operating room.
The sound stopped...
The arm of the director of the anesthesiology department, holding a defibrillator high, was suspended in mid-air. The needle tip of the syringe filled with suspension in the circulating nurse's hand was suspended. Dr. Yamada's body froze. The director of the immunology department's hands trembled slightly. The pupils of the director of neurosurgery shrank sharply.
Everyone's eyes were fixed on the quiet girl on the operating table.
A moment later, the director of the anesthesiology department's sobbing voice woke everyone up: "350 joules! More! Quick!"
350 joules is the highest current allowed in an operating room.
The nurse reacted and quickly adjusted the data: "It's done."
After hearing what the instrument nurse said, the director of the anesthesiology department did not hesitate and pressed again.
Sweat soaked the edge of the director of the anesthesiology department's sterile cap and flowed down his temples. His eyes were bloodshot.
The director of the immunology department also took action and took out epinephrine, injecting 1mg into Aine's body intravenously.
"Beep--" A crisp sound fell into everyone's ears. The director of the anesthesiology department looked up at the electrocardiogram monitor. The electrocardiogram, which had originally been a straight line, suddenly began to beat weakly.
This sudden change rekindled hope for everyone in the operating room.
After a long rescue, using cardiotonic drugs, pressor drugs, adrenaline... all available means were used, and finally, Aine's heartbeat returned to a relatively stable beat.
The director of the anesthesiology department's back was soaked with sweat. He was gasping for breath. After a long period of rescue, he had consumed a lot of physical strength.
Fortunately, Aine's heartbeat resumed, although it was still a little fast, but this was the best result he could achieve.
He looked back at the instrument, the alarm lights on which were flashing at a suffocating frequency.
"Directors, look!" Dr. Yamada's voice cut through the shrill alarms. His voice suddenly rose, trembling with disbelief, his finger practically poking at the screen. "IL-6! TNF-! The peak... the peak is going down! It's going down! Really going down!"
These words were like a bolt of lightning that split the thick dark clouds.
The director of the anesthesiology department suddenly rushed in front of the screen, ignoring his fatigue. His bloodshot eyes were fixed on the curves representing key inflammatory factors.
Dr. Yamada was right. Those lines that had just made people despair now had a tiny but extremely clear downward bend at the top!
The decline is very slight, but the trend is extremely firm!
The circulating nurse stood in front of the screen, stunned: "Is the tocilizumab working? Or is it a hormone shock?"
The head of the immunology department shook his head. "No, although we have a long time to save him, the medicine will take longer to take effect!"
Looking at the abnormal curve, the head of the Immunology Department frowned slightly: "Also... the peak value dropped too steeply..."
As if he had thought of something, the head of the immunology department suddenly turned around and looked at Aine who was unconscious on the operating table, as if he was looking at an incredible miracle.
His voice was filled with ecstasy and shock. "It's her immune system... those CAR-Microglia! The storm is consuming them, but the storm itself is also being weakened by these cells."
"The remaining CAR cells... they started working in the gaps between the storms?" Dr. Yamada was stunned. He had never thought that this would happen, even though all the previous operations had ended in failure.
Dr. Yamada looked at the head of the immunology department. The latter's speculation was so bold as to be almost absurd. In the center of such a violent Category 4 storm, those newly modified microglia, which theoretically should have been completely destroyed by the storm, hadn't completely "died"? The remaining microglia could even weaken the storm during the brief lull?
Dr. Yamada had already given up hope after Aine developed a level 4 cytokine storm. In previous surgeries, the experimental animals could not even survive a level 3 cytokine storm.
Lai1 Linqi IV Gucu Sijiu Ba didn't have time to think about it. The head of the immunology department shouted, "Quick! Increase the life support! Maintain it! Maintain this precious window of time!"
His voice trembled with excitement, but his eyes burned with a new, more intense fire. This seemingly losing battle had unexpected consequences due to the residual CAR cells.
The others nodded, knowing that this might be their only chance.
For the next dozen hours, the operating room became a tug-of-war between doctors and death.
The aftermath of the storm was still dangerous. Ain's liver and kidney functions were once on the verge of collapse, and her lungs were severely effusion. Fortunately, the director of the immunology department started ECMO in advance, and their tubes became the hope of maintaining Ain's fragile life.
The director of the immunology department and the director of the anesthesiology department kept a close eye on the ever-changing monitoring data and adjusted the dosage and treatment plan. From nine in the morning to three in the morning, the cytokine storm was finally barely suppressed.
"Why? It's clearly a level 4 cytokine storm..." Dr. Yamada gasped. Although the air conditioner was on in the operating room, his clothes were still soaked with sweat.
Dr. Yamada looked at the head of the immunology department in confusion: "Not only did they not completely destroy the CAR cells, but they were actually consumed by them?"
The head of the immunology department sat down in a chair, physically exhausted from the long hours of standing and intense surgery. "This is probably because the child just had a cardiac arrest... The cytokine storm paused briefly, giving the CAR cells time to take effect."
"It's a miracle. Clearly none of the animals before... survived." Dr. Yamada sighed.
The head of the immunology department nodded: "After all... the animals we used before are not as big as the human body. The human body has more space for CAR cells to operate."
"That should be the case." Dr. Yamada nodded.
"The patient's condition has finally stabilized," the head of the anesthesiology department breathed heavily. He hadn't performed such a high-intensity operation in a long time. "Send the nurse from the intensive care unit to transfer the patient."
"Okay, I'll contact them right away." The circulating nurse nodded and walked out of the ward quickly.
Hours earlier, Xiangzi and his companions had been persuaded to leave by the circulating nurses. The nurses knew they were worried, but they were blocking the door and could not help at all.
Chapter 385 The Dull Ward
In the ward, the ticking of the clock was deafening.
Deng sat on the ground with her knees hugged, leaning against the wall. Her eyes were bloodshot and her eye sockets were slightly red, as if she had just stopped crying not long ago.
Lixi stood beside the lamp, like a silent comfort.
Mu sat blankly by the bed, her body trembling slightly. Her gaze swept across the brightly lit ward, passing over everyone's faces, and finally stopped on Xiangzi who was sitting next to her.
Mu slowly stretched out her hand, she wanted to grab Xiangzi, trying to get a little comfort.
However, Xiangzi did not notice Mu's actions. The long period of mental tension had caused her attention to be distracted.
When Mu's hand fell on the back of her hand, Xiangzi trembled all over. Noticing the hand that fell on the back of her hand, Xiangzi raised her head and saw that the owner of the hand was Mu. She then breathed a sigh of relief.
Xiangzi raised his other hand and gently patted Mu's hand on the back, then changed to a slightly more comfortable position and continued to think with his head down.
"Tick, tick..." the clock continued to tick, and it was already one o'clock in the morning.
Hailing quietly looked at Miao Meng pacing in front of her. She said softly, "Ruomai, stop."
"Stop?" Miao Meng paused and shook her head. "Sorry, Haizi... I'm very upset."
Hearing Miao Meng say this, Hai Ling sighed softly and didn't say anything more, but as she watched Miao Meng continue pacing, she closed her eyes and stopped looking at her.
Miao Meng was upset, and so was Hai Ling. At six o'clock in the afternoon, the nurse asked them to leave and return to the ward to wait, saying that they would be notified as soon as there was any news. In the end, they waited until one o'clock in the morning, and still no news.
"I don't know when the nurse will come to notify us..." Chu Hua sat on the chair. Because she hadn't drunk water for a long time, her lips were dry and wrinkled, and her voice was a little hoarse.
Not long after Chuhua finished speaking, Aiyin's father walked up to her and handed her a bottle of mineral water: "Little Chuhua, have a drink of water."
"Thank you, uncle... I, I'm not thirsty." Chu Hua waved his hand and declined.
"Your lips are dry and wrinkled. Drink something."
Hearing this, Chuhua realized that her voice had become hoarse. She nodded slightly, did not refuse again, and reached out to take the mineral water from Aiyin's father.
Li Xi squatted down and gently patted Deng's shoulder. The latter slowly turned around: "Li Xi..."
"Deng, don't be too sad..."
"I... I will..." Deng lowered her head and her body began to tremble again. She spoke lightly, but when she really wanted to suppress her inner feelings, she found that she couldn't do it no matter what.
"Rikki..." Lenai, who was squatting on the other side of Lixi, gently grabbed Lixi's trouser leg. Lixi turned around and met Lenai's sad expression.
The moment he saw Lenai's expression, Lixi felt a pang of pain in his heart: "Wild cat..."
"like……"
Before Lenai could say the next word, Lixi quickly covered Lenai's mouth. She looked around and only breathed a sigh of relief after confirming that no one else heard it.
The atmosphere in the ward is now terribly depressing. Li Xi knows that Lenai wants to ask about Aine, but if he really lets Lenai say it, Li Xi can't guarantee that this will not become the fuse that ignites other people's emotions.
"Shh." Li Xi made a silent gesture, then she gently rubbed Lenai's head, "Don't worry, everything will be fine."
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